| Quantity: | |
|---|---|
Product Advantage
1.Water solubility:
It can be mixed with water in any proportion to form a clear and transparent solution. Even at low temperatures, it dissolves relatively quickly without phase separation.
2.Film-forming property:
After drying, it forms a transparent, flexible, and glossy film. This film has strong adhesion, is not easily brittle, and also provides a certain degree of breathability.
3.Adhesive property:
It shows good adhesion to various substrates such as metals, plastics, and fibers, and is commonly used as a binder in tablets and granules.
4.Chemical stability:
It is relatively stable at room temperature and not easily decomposed. However, it may undergo certain changes under high temperature, strong acids, or strong alkali conditions.
Technical Parameters
Polyvinylpyrrolidone K90 | |||
Chemical Name:2-Pymolidinone,1-ethenyl-,homopolymers | |||
Test Items | Parameters | Parameters | Parameters |
Appearance | White to off-white | White to yellowish-white | Whiteto yellowish-white |
ldentification | / | According to cosmetic | According to USP |
K value | ≥90 | ≥90 | ≥90 |
Solid content | 95%-100% | 1 | 1 |
Moisture | 1 | ≤5.0% | ≤5.0% |
PH Value(5%in water) | 4.0-7.0 | 4.0-7.0 | 4.0-7.0 |
1-Vinylpyrrolidin-2-one | ≤0.1% | ≤0.001% | ≤0.001% |
Residue on ignition | 1 | ≤0.1% | ≤0.1% |
Nitrogen | 1 | 11.5%-12.8% | 11.5%-12.8% |
Aldehydes | / | ≤0.5% | ≤0.05% |
Heavy metals ppm | / | ≤10 | ≤10 |
Hydrazine ppm | / | ≤1.0 | ≤1.0 |
Micro organism ppm | 1 | 1 | 1 |
Peroxides ppm | 1 | 1 | ≤400 |
2-Pyrrolidone | 1 | ≤3% | ≤3% |
Formic acid | / | / | ≤0.5% |
Polyvinylpyrrolidone K30 | |||
Chemical Name:2-Pymrolidinone,1-ethenyl-,homopolymers | |||
Test Items | Parameters | Parameters | Parameters |
Appearance | White to yellowish-white | White to yellowish-white | Whiteto yellowish-white |
ldentification | According to USP | According to USP | According to USP |
K value | 27-32 | 27-32 | 27-32.4 |
Moisture | ≤5.0% | ≤5.0% | ≤5.0% |
PH Value(5%in water) | 3.0-5.0 | 3.0-5.0 | 3.0-5.0 |
1-Vinylpyrrolidin-2-one | ≤0.1% | ≤0.1% | ≤0.01% |
Residue on ignition | ≤0.1% | ≤0.1% | ≤0.1% |
Nitrogen | 1 | 11.5%-12.8% | 11.5%-12.8% |
Aldehydes | 1 | ≤0.5% | ≤0.05% |
Heavy metals ppm | 1 | ≤10 | ≤10 |
Hydrazine ppm | 1 | ≤1.0 | ≤1.0 |
Micro organsm ppm | 1 | 1 | 1 |
Peroxides ppm | 1 | ≤400 | ≤400 |
2-Pyrrolidone | 1 | 1 | ≤3% |
Formic acid | / | 1 | ≤0.5% |
Product Uses
In the pharmaceutical field, anhydrous piperazine can be used as a pharmaceutical intermediate for the production of anthelmintic drugs, analgesics, antitumor agents, antibacterial drugs, antiallergic drugs, antidepressants, and antiemetics. Phenylpiperazine derivatives can also be absorbed by the human body and mimic the secretion of dopamine, an important neurotransmitter, thereby helping to stabilize and regulate mood.
In the field of organic chemistry, anhydrous piperazine is soluble in water, alcohols, and other liquids, and can react with acids. When formulated in appropriate proportions, it can be used in the production of surfactants, flame retardants, and compound additives.
In the agrochemical field, when added to pesticides, it can effectively control plant diseases and insect pests and protect crops. It is used in the production of fungicides and insecticides.
FAQ
What is the mechanism of action of anhydrous piperazine?
The mechanism of piperazine is that it blocks cholinergic receptors at the neuromuscular junction, thereby inhibiting the transmission of nerve impulses and the excitatory effect of acetylcholine. As a result, parasites become paralyzed without prior excitation, making it relatively safe in use.After oral administration, it is rapidly absorbed from the gastrointestinal tract. A portion is metabolized in the body, while the remainder is excreted via the kidneys. Its various salts all convert into piperazine hexahydrate in solution, and their absorption and excretion are generally similar, although the excretion rate varies significantly among individuals.
What safety precautions should be taken when handling anhydrous piperazine due to its chemical reactivity?
Anhydrous piperazine has a certain degree of chemical reactivity and may pose hazards when mixed with other chemicals. Contact or mixing with strong oxidizing agents, strong acids, strong bases, and other incompatible substances should be avoided.When handling anhydrous piperazine, precautions should be taken to prevent sparks, static electricity, and other fire and explosion risks.
