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Product Advantage
1.Excellent Water Solubility and Compatibility
The presence of hydroxyl and amine groups gives the molecule strong hydrophilicity, allowing it to be highly compatible with water and various polar systems. It is suitable for a wide range of aqueous reactions and formulation systems.
2.High Reactivity and Easy Derivatization
With both amine basicity and hydroxyl reactivity, it can participate in various organic reactions such as substitution and acylation, making it a versatile and important chemical intermediate.
3.Good Thermal and Chemical Stability
Due to its relatively high boiling point and stable structure, it is not easily decomposed under normal industrial conditions, making it convenient for storage and processing.
4.Low Volatility and Safer Handling
Its low vapor pressure and high flash point result in minimal volatilization during production and use, ensuring improved operational safety.
5.Strong Versatility Across Multiple Applications
It is widely used in pharmaceuticals (e.g., as an intermediate for fluphenazine), agrochemicals, surfactants, and organic synthesis, offering broad application scope and high commercial value.
Technical Parameters
Chemical name | Hydroxyethylpiperazine,also known as piperazine ethyl alcohol |
CAS NO | 103-76-4 |
Molecular formula | C6H14N20 |
Molecular weight | 130.19 |
Physicaland chemica properties | Colorless or light yellow transparent viscous liquid |
Boiling point | 246℃ |
Relative density | 1.061 |
Refraction rate | 1.5065 |
Content | ≥99% |
Water content | ≤0.3% |
Piperazine | ≤0.2% |
Water content | ≤0.3% |
Piperazine | ≤0.2% |
Packing | 200kg PE drum. |
Appearance | Colorless orlight yellow transparent viscous liquid; |
Product Uses
In industrial synthesis, one of the most important applications of hydroxyethylpiperazine is as an intermediate or raw material for key amine compounds such as triethylenediamine (TEDA). It is widely involved in the preparation of catalyst systems and polymer-related materials, and is particularly significant in the polyurethane industry.
In the field of surfactants, it is used to synthesize functional surfactants with excellent emulsifying, dispersing, and wetting properties. These products are widely applied in personal care products, industrial cleaning agents, and specialty chemical formulations.
In the pharmaceutical industry, hydroxyethylpiperazine is not only used in the synthesis of intermediates for antipsychotic drugs such as fluphenazine, but also serves as a building block for various nitrogen-containing heterocyclic drugs. It plays an important role in constructing bioactive molecular structures, making it highly valuable in fine pharmaceutical chemistry.
In agrochemicals, it can be used as an active intermediate in the synthesis of herbicides, insecticides, and fungicides, helping to enhance molecular diversity and optimize biological activity in pesticide design.
FAQ
What functional groups does hydroxyethylpiperazine contain and why are they important?
Hydroxyethylpiperazine contains both a hydroxyl group (-OH) and amine groups (-NH-). These functional groups give it high water solubility and strong reactivity, making it suitable as a versatile intermediate in organic synthesis and industrial applications.
What are the storage conditions for hydroxyethylpiperazine?
Hydroxyethylpiperazine should be stored in a cool, well-ventilated warehouse. It must be kept away from ignition sources and heat. It should be stored separately from oxidizing agents, and mixed storage is strictly prohibited.Explosion-proof lighting and ventilation systems should be used. Mechanical equipment and tools that may generate sparks are not allowed.The storage area should be equipped with emergency leakage response equipment and appropriate containment materials.
