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Product Advantage
1.High Purity & Consistent Quality
Typically ≥99.5% purity, ensuring reliable performance and consistent results in downstream applications.
2.Highly Reactive & Versatile Intermediate
Featuring both a pyrazine ring and a cyano group, it offers excellent reactivity, making it ideal for a wide range of chemical transformations and synthesis processes.
3.Stable & Easy to Handle
Exhibits good chemical stability under normal storage conditions, allowing for safe transportation and long shelf life.
4.Wide Application Range
Suitable for pharmaceuticals, flavors & fragrances, and other fine chemical industries, providing flexibility for various formulations.
5.Process-Friendly Properties
Moderate boiling and melting points make it easy to control during synthesis, purification, and scale-up production.
Technical Parameters
CAS NO. | 19847-12-2 |
Freezing point | 18-20℃ |
Boiling point | 84-87℃(18-20mmHg) |
Specific weight | D2020=1.130-1.230 |
Refractive index | N2020=1.530-1.540 |
Water(%) | 0.50% |
Analytical purity(%) | 99.50%(gas chromatography) |
Product Uses
1.Synthesis of Anti-Tuberculosis Drugs
It serves as a key raw material for the synthesis of pyrazinamide, an important drug used in the treatment of tuberculosis.
2.Organic Synthesis
It is widely used as an intermediate in organic synthesis, participating in various reactions such as nucleophilic substitution and coupling reactions.
3.Flavors, Fragrances & Pharmaceuticals
It is extensively applied in the flavors, fragrance, and pharmaceutical industries as a valuable intermediate.
4.Surfactants, Coatings & Solvents
It can also be used in the preparation of surfactants, solvents, and coating materials.
FAQ
What functional groups are present in 2-cyanopyrazine and how do they influence its reactivity?
2-Cyanopyrazine contains a pyrazine ring and a cyano group (–CN). The electron-withdrawing nature of both structures increases its electrophilicity, making it highly reactive and suitable for various organic synthesis reactions such as nucleophilic substitution and coupling.
Why is 2-cyanopyrazine considered an important pharmaceutical intermediate?
It is a key starting material for the synthesis of pyrazinamide, an anti-tuberculosis drug. Its stable structure, high purity, and good reaction efficiency make it widely used in pharmaceutical manufacturing processes.
