The role of 1,2 hexadiol in cosmetic ingredients

1, 2-hexadiol is a kind of polyol, colorless and transparent in appearance, with mild sweet flavor. As a cosmetic raw material, it has a good bactericidal and moisturizing effect (antibacterial mechanism: it can enter the cell membrane of microorganisms, then destroy the integrity of the cell membrane, let the cell fluid penetrate out, and finally lead to the death of microorganisms). At the same time, it has no sensitive side effects on human skin. It is precisely because 1, 2-hexadiol has antibacterial effects and is not on the list of preservatives that it is often used as an alternative preservative in non-preservative systems.

Step 1 Moisturize Kong Qiucan et al. studied the moisturizing effect of 1, 2-hexanediol. The moisturizing effect of 0.5% 1, 2-hexanediol is slightly better than 3.0% glycerol, which has a very good moisturizing effect. Moreover, the viscosity of 1, 2-hexanediol is lower than glycerol, and it has a more suitable skin feeling when used in products.

2, instead of anti-corrosion – single antibacterial

Kong Qiuchan et al studied the antiseptic effect of 1, 2-hexadiol alone. Adding 1, 2-hexanediol alone to the water agent had good inhibitory effect on Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. When the mass fraction of 1, 2-hexanediol was 2.0%, all the three strains were killed on the second day.

3, instead of anti-corrosion – compound antibacterial

Since 1, 2-hexanediol has a good inhibitory effect on bacteria and a slightly weak inhibitory effect on fungi, in order to achieve better antibacterial effect, it needs to be combined with other alternative anti-corrosion ingredients, such as p-hydroxyacetophenone, 1,2 pentanediol, octyl glycol, ethylhexyl glycerol, etc. Kong Qiuchan et al studied the anti-corrosion effects of the combination of 1, 2-hexadiol and propylene glycol as follows

0.5%, 1, 2-hexanediol combined with 0.2% propylene glycol;

0.5%, 1, 2-hexanediol combined with 0.3% propylene glycol;

0.8%, 1, 2-hexanediol combined with 0.2% propylene glycol;

0.8%, 1, 2-hexanediol combined with 0.3% propylene glycol;

Summary: 1, 2-hexadiol is a kind of polyol, which has the function of moisturizing and bacteriostatic. In terms of bacteriostasis, 1, 2-hexadiol has a very obvious inhibitory effect on bacteria and yeast.