1.2 Hexadiol moisturizing preservative Introduction

Chemical name: 1, 2-hexadiol
CASNo: 6920-22-5
Molecular formula: C6H14O2
1, 2-hexadiol is a very safe and effective humectant with a wide range of antibacterial and preservative properties.
Physical and chemical data
Appearance: Colorless transparent liquid
Smell: Characteristic smell
Content: ≥99%
Density (20℃) : 0.946-0.956
Refractive index (25℃) : 1.437-1.447
Solubility: Soluble in water
1, 2-hexadiol is a kind of polyol, the appearance is colorless and transparent, as a cosmetic raw material, has a good bactericidal and moisturizing effect (antibacterial mechanism: it can enter the cell membrane of microorganisms, and then destroy the integrity of the cell membrane, so that the cell fluid penetrates out, and finally leads to the death of microorganisms), and has no sensitive side effects on human skin. 1, 2-hexadiol has good miscibility with other substances (easily soluble in water, ethanol, etc.), and can be well combined with other anti-microbial substances to play an antibacterial and anti-sensitive role. In addition, there are also reports that 1, 2-hexanediol is used in deodorant, which has obvious deodorizing and antiperspirant effect on human skin, and is gentle to the skin.

Antiseptic effect of 1, 2-hexadiol alone. As shown in the figure below, 1, 2-hexanediol has a good inhibitory effect on Staphylococcus aureus, Escherichia coli and pseudomonas aeruginosa. When the mass fraction of 1, 2-hexanediol is 2.0%, all the three bacteria have been killed on the second day. However, the killing ability of 1, 2-hexanediol against P. albicans and Aspergillus Niger was obviously weak. When the mass fraction of 1, 2-hexanediol was 2.0%, it could be completely killed on the 7th and 21st day, respectively.

The test results of antiseptic challenge of 1, 2-hexadiol on mixed bacteria and mixed fungi in water are shown in the figure below. When the mass fraction of 1, 2-hexadiol is 1.5%, it has shown excellent antiseptic ability on mixed bacteria, and the inoculated bacteria can be completely killed on the second day. Similar to the test results of single inoculation of Aspergillus Niger, 1, 2-hexadiol has a weak anti-corrosion ability to the mixed fungi, and can completely kill the mixed fungi on the 21st day when its mass fraction is 2.0%.

1, 2-hexadiol is a kind of polyol, which has the function of moisturizing and bacteriostatic. In terms of bacteriostasis, 1, 2-hexadiol has a very obvious inhibitory effect on bacteria and yeast, but the inhibitory effect on mold is slightly weak. Therefore, when used as an alternative anticorrosion, 1, 2-hexanediol needs to be combined with other ingredients, for example, 1, 2-hexanediol and p-hydroxyacetophenone can pass the anticorrosion challenge test when the addition amount is (mass ratio) 0.5:0.5.

Product advantage

Excellent quality, high purity above 99.8%, odorless.

Excellent safety, more gentle, safe, non-irritating.

It has broad spectrum antibacterial activity and can play a good bactericidal and bacteriostatic effect.

As a moisturizing agent and skin conditioning agent, it has the function of moisturizing and moisturizing at the same time.

Worldwide approved multi-functional cosmetic additive.

Combined with traditional preservatives and no added preservatives, it can play an obvious synergistic effect.

Good compatibility, high formula flexibility, widely used in personal care products.

Recommended application

Instead of traditional preservatives such as formaldehyde releasers, methyl isothiazolinones, and paraben esters, which have a single anti-corrosion effect and certain side effects.

Sensitive skin care products and other personal care products anti-corrosion system.

The additive formulation system claims to be safe, mild and non-irritating.

The formula system can increase efficiency, prevent corrosion and reduce original irritation.

Facial care, hair care, body care and other personal care products.

1, 2-hexanediol is added to daily necessities and used as a preservative in contact with the human body, which has the effect of sterilization and moisturizing, and does not have a negative effect on human health. Many patents or articles mention that 1, 2-hexanediol and other substances with anti-microbial effects can play an anti-microbial effect. P&g adds 1, 2-hexadiol to deodorants and antiperspirants, resulting in a deodorant/antiperspirant that is better at deodorizing/antiperspirant, with better skin feel, clarity, and gentler on the skin. The United States has added 1, 2-hexadiol to eyelid lotion, Givudan Co., Ltd. and Japan’s Yoshiko Co., Ltd. have also added 1, 2-hexadiol to skin care compositions in place of other antiseptic preservatives. Dow Global Technologies uses 1, 2-hexadiol instead of alcohol to add to the perfume, both to reduce skin irritation, and because of its excellent solvent and solubability, reduce the use of surfactants to achieve a more stable product. Chinese cosmetics companies have also added 1, 2-hexadiol to cosmetics, which is bactericidal and preservative and less irritating to the skin, improving the safety of skin care products.