PVPK30 effect of polyvinylpyrrolidone

Like all homopolymer series products, because the molecular structure of PVPK30 contains hydrophilic groups and oil groups, it can interact with many solvents, so that it can be dissolved in water, and can be dissolved in a variety of alcohols, carboxylic acids, amines and halogenated organic solvents. The solubility is limited only by its own viscosity.

Basic information

Polyvinylpyrrolidone is a ketone organic matter, which can be used as clarifying agent. Stabilizer; Thickening agent; Tablet filler; Dispersant. Molecular weight of 360,000 polymer PVP is commonly used as beer, vinegar, wine and other clarifying agents.

CAS number: 9003-39-8

Molecular formula: C6H9NO

Molecular weight: 111.142

Precision mass: 111.068

PSA: 20.310

Logp: 0.690

IUPAC: 1-Ethenylpyrrolidin-2-One

Heterogeneous SMILE: C=CN1CCCC1=O

Attribute classification

Substance category: organic matter

Category: Polymer (materials) > Other polymers, apis and intermediates > Blood system drugs

Physicochemical property

Melting point: 165℃

Density: 1,69G/Cm3

Appearance and shape: White to yellowish white powder

Povidone K30

The molecular weight of PVPK30 is about 40000, which is one of the most used homopolymer series products.

Product name :PVP-K30 POvidone K30

Chemical name: 1-vinyl-2-pyrrolidone homopolymer

CTFA Name :POLYVINYLPYRROLIDONE(PVP)

Physical properties:

Solubility and solution properties

As with all homopolymer series products, because the molecular structure of PVPK30 contains hydrophilic groups and oil groups, it can interact with many solvents, so that it can be dissolved in water, but also can be dissolved in a variety of alcohols, carboxylic acids and halogenated organic solvents. The solubility is limited only by its own viscosity.

PVPK30 can be dissolved in a variety of organic solvents, so that it has a wide range of applications in the production of water treatment film, is an excellent membrane pore-causing agent. Taking PVDF hollow fiber membrane as an example, PVPK30, PVDF and other fillers are dissolved in organic solvents such as DMF or DMAc to make the casting film liquid. After processing by subsequent processes such as spinning, it is gelatinized in water phase or alcohol phase to make a membrane filament with uniform pore size.

Surface activity

The molecule of PVPK30 has a butyractam structure and contains a more polar lactam group with a dipole moment of 40, which is capable of hydrophilic and polophilic groups. In addition, there are non-polar methylene (-CH2-) and submethylene (-CH=) groups in its molecular ring and long chain, making it lipophilic. The environment of the two ends of the amide group in the dipole moment of the molecule is also different, from the molecular model, the end of the oxygen atom is bare, and the end containing the N atom is just surrounded by methyl and methylene. This molecular structure of PVPK30 makes it surface active and can be used as a polymer surfactant.

Complexability

PVPK30 is a polymer with a high “dissolving” ability, which is due to the high polarity of its molecular structure and the ability to accept the hydrogen chain of amide groups, while also having non-polar groups. Both groups have the ability to “dissolve” the corresponding groups on small molecular components. This ability enables PVP

To form solid complexes with many substances, especially compounds containing hydroxyl, carboxyl, amino and other active chlorine atoms.

Film forming and hygroscopicity

PVPK30 can be poured or coated from a solution of water, methyl alcohol, ethanol, chloroform or dichloroethane. The formed film is colorless and transparent, hard and bright, and the solvent has no effect on the generated film. PVPK30 has strong hygroscopic ability, which is weaker than carboxymethyl cellulose (CMC), but stronger than PVA. Once the PVPK30 is hygroscopic, it will show a certain bonding property. The hygroscopic equilibrium water content of PVPK30 is about 1/3 of the relative humidity.

Applications:

Application of industrial grade PVP :PVP-K series can be used as film agent, thickener, lubricant and adhesive in daily chemical industry, used for eruption, moss, hair gel, hair solution, etc., in skin care hair dye, modifier, foam stabilizer of shampoo, dispersant and affinity in wave styling agent, in snow cream, sunscreen add PVP to enhance wetting and lubrication effect. Secondly, adding PVP to the detergent has a good anti-color effect, and can enhance the cleaning ability. Application of PVP in industrial and high-tech fields :PVP in pigments, printing inks, textiles. It can be used as surface coating agent, dispersant, thickener and adhesive in printing and dyeing and color picture tube. PVP can improve binder on metal. In addition,PVP in the separation membrane, ultrafiltration membrane, microfiltration membrane, nanofiltration membrane, oil mining, light solid resin, paint and coatings, optical fiber, laser disc and other emerging high-tech applications are also increasingly widespread. In short, Pvp series products have excellent performance and are widely used in medicine, coatings, pigments, resins, fiber inks, adhesives, cleaning agents, textile printing and dyeing additives. As a polymer surfactant, Pvp can be used as dispersant, emulsifier, thickener, leveling agent, viscosity regulator, anti-reproducing liquid agent, coagulant, co-solvent and detergent in different dispersion systems. Application of medicinal grade PVP: PV-K series k30 is one of the synthetic excipients to be used, mainly used for the production of tablets, granules binder, sustained release agent, injection adjuvant and stabilizer, flow aid, liquid preparation and coloring agent dispersant, enzyme and heat sensitive drug stabilizer. Co-precipitating agent for refractory drugs, delay agent for ophthalmic drugs, lubricant and coating film forming agent.