Introduction to glacial acetic acid

Glacial acetic acid

Acetic acid, also known as acetic acid (36%-38%), glacial acetic acid (98%), chemical formula CH3COOH, is an organic monic acid, the main component of

vinegar. Pure anhydrous acetic acid (glacial acetic acid) is a colorless hygroscopic solid with a freezing point of 16.6 ° C (62 ° F) and becomes a colorless crystal

after solidification. Its aqueous solution is weakly acidic and erosive, and the steam is irritating to the eyes and nose.

【 Basic Information 】

Chinese name:Acetic acid
Another name:Glacial acetic acid. Acetic acid
Chemical formula:CH3COOH

Molecular weight:60.05

Fusing point:16.6 ℃

CAS login number:64-19-7

Boiling point:117.9 ℃

Flash point:39 ℃
Relative density (water is 1):1.050
Freezing point (℃):16.6
Viscosity (mPa.s):1.22 (20℃)
Vapor pressure at 20℃ (KPa):1.5
Drug classification

Antiseptic preservative – glacial acetic acid

Appearance and smell

Colorless liquid with a pungent acetic acid smell.

solubility

Soluble in water, ethanol, ether, carbon tetrachloride and glycerol and other organic solvents.

【 Function 】

Acetic acid can be used as acidity regulator, acidifier, pickling agent, flavor enhancer, fragrance and so on. It is also a good antimicrobial agent, mainly due to its

ability to reduce the pH below the pH required for optimal microbial growth. Acetic acid is the earliest and most used sour agent in China. It is mainly used in

compound seasoning, preparation of wax, canned food, cheese, jelly and so on. When used in seasonings, acetic acid can be diluted with water to 4%~5% solution and added to a variety of seasonings. The beverage made of vinegar as a sour agent and supplemented by pure natural nutrition and health products is called the international third generation beverage.

【 Toxicological data 】

Acute toxicity: LD50:3.3 g/kg(rat transoral); 1060mg/kg(rabbit percutaneous). LC50:5620ppm, 1h(mouse inhalation); 12.3g/m3,1h (inhaled by rats). The

minimum amount of intoxication was 1.47mg/kg in the mouth, and symptoms of digestive tract appeared. Human oral 20 ~ 50g, lethal dose. Acetic acid at 80%

concentration can cause severe skin burns in guinea pigs, 50% to 80% produce moderate to severe burns, less than 50% is very mild, and 5% to 16%

concentrations never cause burns. Human can not tolerate more than 3min in 2~3g/m3 concentration. The oral lethal dose for humans is 20-50g.

Subacute and chronic toxicity: When the concentration of this product is about 100mg/m3, the chronic effect can cause inflammation in the nose, nasopharynx,

eyelid and throat of workers, and even cause bronchitis. People inhaled (200 ~ 490) mg/m3× (7 ~ 12) years, there are eyelid edema, conjunctival congestion,

chronic pharyngitis, bronchitis and other symptoms.

Mutagenicity: Microbial mutagenicity: E. coli 300ppm(3h). Sister chromatid exchange: human lymphocytes 5mmol/L.

Reproductive toxicity: The lowest oral toxic dose (TDL0) of rats was 700mg/kg(18 days after delivery), which had an effect on the behavior of newborn rats. The

lowest toxic dose (TDL0) in the testis of rats was 400mg/kg(1d, male), which had an effect on the male fertility index.

Health hazard: The way of invasion is inhalation, ingestion and transdermal absorption. Irritant to nose, throat and respiratory tract when inhaled. It has a strong irritating effect on the eyes. Skin contact, mild erythema, severe cause chemical burns. Ingestion of concentrated acetic acid can lead to erosion in the mouth and digestive tract, and death can be caused by shock in severe cases.

Chronic effects: eyelid edema, conjunctival congestion, chronic pharyngitis and bronchitis. Long-term repeated contact can cause dry skin, degreasing and

dermatitis.

Environmental harm: It is harmful to the environment and can cause pollution to water.

【 Safety and Protection 】

Flash point (° C) : 39

Explosion limit (%) : 4.0 ~ 17

Electrostatic action: May have polymerization hazard

Flammability: Spontaneous combustion temperature: 463℃

Dangerous characteristics: It can react strongly with oxidants, and react violently with sodium hydroxide and potassium hydroxide. It is corrosive to metals when diluted.

Acetic acid in higher concentrations is corrosive and can cause skin burns, permanent blindness and inflammation of the mucous membranes, so proper protection is needed. These burns or blisters do not necessarily appear immediately, and most cases occur several hours after exposure. Latex gloves do not provide protection, so special gloves such as nitrile rubber gloves should be worn when handling acetic acid. Concentrated acetic acid is difficult to burn in the laboratory,but it poses a combustible threat at ambient temperatures of 39 ° C (102 ° F), above which acetic acid can mix with air and explode (explosion limit 4% to 17% by volume concentration).

Leakage treatment

Pollution emission category: Z

Leakage treatment: cut off the fire source, wear protective glasses, gas masks and acid-resistant work clothes, wash the spill with a lot of water, so that it flows

into the channel and is quickly diluted, thereby reducing the harm to the human body.

Fire extinguishing method

Use mist water, dry powder, anti-alcohol foam, carbon dioxide, extinguishing. Keep the container in the fire cool with water. A mist of water is used to disperse the vapor and drive away the leaking liquid so that the dilution becomes a non-combustible mixture. And spray with water to remove the personnel.

First aid

Skin contact: Wash skin contact with water first, then wash thoroughly with soap.

Eye contact: If the eyes are irritated, wash them with water and wipe them with a dry cloth. In serious cases, send them to the hospital for diagnosis and

treatment.

Inhalation: If the vapor is inhaled, the patient should be removed from the contaminated area, placed to rest and keep warm.

Ingestion: Gargle immediately after ingestion, give emetics to induce vomiting, and be sent to hospital for diagnosis and treatment.

Protective measure

Respiratory system protection: Wear a gas mask when the depth concentration in the air exceeds the standard.

Eye protection: Wear chemical safety glasses.

Hand protection: Wear rubber gloves.

Other: After work, shower and change clothes, do not bring work clothes into the living area.

Safety information

RTECS number: AF1225000

Dangerous goods mark :C :Corrosive

Risk term: R10

Security term: S23

Security terminology

Do not inhale steam.

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

If you have an accident or feel unwell, seek medical attention immediately (show the label if possible).

Risk terminology

Flammable.

Causing severe burns.

【 Storage and transportation 】

Storage management

Store in a cool, ventilated warehouse. Keep away from fire and heat. During the freezing season, the temperature of the reservoir should be kept above 16℃ to

prevent solidification. Keep the container sealed. It should be stored separately from oxidants and alkalis, and should not be mixed. Explosion-proof lighting and

ventilation facilities are adopted. Do not use mechanical equipment and tools that are prone to spark. The storage area should be equipped with leak emergency

treatment equipment and suitable containment materials.

Management of transportation

The time limit for railway transportation of this product is the use of aluminum enterprises to prepare tank cars for shipment, and the approval of relevant

departments is required before shipment. Non-canned railway transport should be in strict accordance with the Ministry of Railways “dangerous goods transport

Rules” in the dangerous goods packing table. The packing should be complete and the loading should be secure. During transportation, it is necessary to ensure

that the container does not leak, collapse, fall or damage. The tank (tank) car used in transportation should have a grounding chain, and a hole partition can be

provided in the tank to reduce static electricity generated by shock. It is strictly prohibited to mix or transport with oxidants, alkalis and edible chemicals. Road

transport should follow the prescribed route, do not stay in residential areas and densely populated areas.