Cross-linked POvidone PVPP
Product name: Crosslinked POvidone
Pharmacopoeia name: Crosslinked POvidone
Chemical name: Crosslinked polyvinylpyrrolidone,PVPP
INCI/CTFA:InsolublePVP
CAS number :9003-39-8,25249-54-1
Packing: 20KG.50KG/ cardboard drum, etc
Description White or near white, with hygroscopic easy to flow powder, odorless or slightly odorless, insoluble in water, alkali, acid and common organic solvents, with strong swelling performance and complex ability with many kinds of substances. Therefore, it is considered to be the preferred disintegrating agent for high-grade tablet drugs, especially suitable for the formulation of instant, chewable tablets. It has been included in the US Pharmacopeia Version 28 and the European Pharmacopeia version 5.0. In addition, food grade products are also widely used in the beer and beverage industry.
As we all know, crosslinked POvidone is one of the three super disintegrators, however, it can not only be widely used as medicinal excipients in pharmaceutical preparations, but also as a food additive used in the processing and production of beer, red wine, juice and other drinks, so it has another name – insoluble polyethylene pyrrolidone (PVPP).
Due to the characteristics of PVPP’s own structure, its powder particles have a multi-pore microstructure and a high specific surface area. It can effectively adsorb polyphenols in the wine body through complexation, maintain the clarification and stability of the wine body, prevent turbidity and precipitation, and significantly improve the color, taste and stability of the wine body.
Adsorption mechanism of PVPP
The molecular structure of the polymer limits the internal hydrogen bonds and maximizes the number of possible reaction sites to reduce the required level of PVPP addition in beer.
How to use PVPP
The PVPP is prefabricated into 8-12% slurry with deoxidized water, and it is left for about 1 hour to make the particles of PVPP fully absorb water and spread out, improve the adsorption efficiency, mix it alone or with other additives such as diatomaceous earth and add it to beer, and fully contact for more than 5-10 minutes after the adsorption is completed, the beer can be completely removed from the PVPP in the body.
Should be used:
1) Beverage and wine industry: PVPP is an insoluble, high molecular weight crosslinked compound with excellent adsorption properties. PVP-P can be used safely and efficiently in the beverage and wine industry because:
Completely insoluble in beer (red wine, juice, etc.);
Significantly increase container storage time for beer (wine, juice, etc.);
Suitable for any kind of beer (wine, juice, etc.);
Improve the taste of beer (wine, juice, etc.) at the same time has no adverse effect on the foam, flavor and so on;
Very efficient, easy to operate and make full use of existing equipment;
Compared with the conventional use of silica gel, the unit mass PVP-P beer (wine, juice, etc.) processing capacity is larger;
2) Pharmaceutical industry: PVPP, as a disintegrant, has very excellent properties. Due to its combined properties of high swelling pressure, high capillary activity, and remarkable hydration ability, PVPP is ideally suited for use as a tablet disintegrator in pharmaceutical systems. PVPP and polyphenol can form stable complexes, which can be used to refine water-soluble or alcohol-containing herbal extracts and tinctures to improve the stability of plant medicine. It has been included in the US Pharmacopeia Version 28 and the European Pharmacopeia version 5.0.
