dmso solution
Chemical name: Dimethyl Sulfoxide
CAS: 67-68-5
MF: C2H6OS
Specification
Application:
DMSO can be used as organic solvent, reaction medium and organic synthesis intermediate. Extremely versatile. This product has high selective extraction ability, and is used as a polymerization and condensation solvent for acrylic resin and polysulfone resin, a polymerization and filament solvent for polyacrylonitrile and acetate fiber, an extraction solvent for the separation of alkanes and aromatics, and a reaction medium for aromatic hydrocarbons, butadiene extraction, acrylic spinning, plastic solvents and organic synthetic dyes, pharmaceuticals and other industries. In medicine, dimethyl sulfoxide has anti-inflammatory and analgesic effects, and has strong penetration into the skin, so it can dissolve certain drugs, so that such drugs can penetrate into the human body to achieve therapeutic purposes.
Packing: 230kg/drum, IBC, ISOTANK
Storage:Keep the warehouse ventilated, keep away from open flames, high temperature, keep the container sealed.
Dimethyl sulfoxide (DMSO) is an organic solvent that has many chemical and biological applications.
1. Chemical properties: DMSO is a colorless, odorless, highly volatile liquid, liquid at room temperature. It is a polar solvent that can dissolve many organic and inorganic compounds.
2. Solubility: DMSO can dissolve many organic and inorganic substances, including many non-soluble compounds.
3. Biocompatibility: DMSO is widely used in the medical field because it has good permeability to biological tissues and is compatible with many biomolecules.
4. Oxidation: DMSO can be used as an oxidant or reducing agent to participate in some chemical reactions.
5. Toxicity: Although DMSO is considered relatively safe in many applications, high concentrations of DMSO can be toxic to some biological tissues.
Dimethyl sulfoxide (DMSO) has a variety of uses, including but not limited to the following:
1. Organic synthesis: DMSO is an important polar solvent and is widely used in organic synthesis. It is able to dissolve many organic substances, helping to promote chemical reactions.
2. Pharmaceutical field: DMSO is used as a solvent and carrier of drugs in the pharmaceutical field to help drugs penetrate into biological tissues. In addition, it is also used for topical applications in the treatment of diseases such as arthritis.
3. Biochemical research: DMSO, as a solvent or additive, is often used in biochemical research fields such as cell culture, protein purification and analysis.
4. Health products and cosmetics: DMSO is sometimes used in health products and cosmetics for its penetrative properties and moisturizing effects.
5. Industrial applications: DMSO can also be used for industrial purposes such as lubricants, solvent extractants, solvents and additives for resins.
These are just some of the main uses of DMSO, and there are some other special applications for the substance.
The upstream products of dimethyl sulfoxide (DMSO) are methionyl chloride and dimethylamine. Methionyl chloride reacts with dimethylamine to form DMSO.
DMSO’s downstream products and derivatives are numerous, including:
1. Various organic synthesis intermediates: DMSO can be used as a solvent and catalyst for organic synthesis, producing various organic compounds in many synthetic reactions.
2. Pharmaceutical preparations: DMSO can be used as a drug carrier and solvent for topical drugs or to promote drug penetration into biological tissues.
3. Cosmetics and health care products: DMSO is also used in cosmetics and health care products due to its moisturizing and penetrating properties.
4. Industrial use: DMSO can also be used as lubricants, solvents for resins and additives in industrial products.
These are some of DMSO’s main upstream and downstream products, of which the downstream products have quite a wide range of applications.
The synthesis route of dimethyl sulfoxide (DMSO) mainly involves the following steps:
1. Methionyl chloride reacts with dimethylamine: First, methionyl chloride reacts with dimethylamine to form dimethyl sulfoxyl chloride.
2. Sodium sulfite treatment: The resulting dimethyl sulfoxide chloride is then reacted with sodium sulfite to form dimethyl sulfoxide.
This is the main synthetic route of DSO, which involves two key chemical reaction steps. This synthetic route has been widely used in industrial production.
Dimethyl sulfoxide (DMSO) transportation and storage needs to pay attention to the following points:
1. Packaging: DMSO should be packaged in a sealed container during transportation to prevent leakage.
2. Transportation: DMSO is a dangerous chemical and needs to be transported in accordance with the corresponding regulations on the transportation of dangerous chemicals to avoid improper reactions with other substances.
3. Temperature: DMSO should be transported and stored within the specified temperature range. Normally, normal transport and storage can be carried out at room temperature.
4. Fire prevention: DMSO is a flammable liquid, and it is necessary to pay attention to fire prevention and static accumulation during transportation and storage.
5. Storage: DMSO should be stored in a cool, dry and well-ventilated place, away from heat and fire, and away from direct sunlight.
In general, the transportation and storage of DMSO need to be strictly operated in accordance with relevant regulations and standards to ensure safety and stability.
Note the following when using dimethyl sulfoxide (DMSO) :
1. Protective measures: When exposed to DMSO, adequate personal protection should be taken, including wearing chemical protective clothing, goggles and protective gloves.
2. Ventilation: Good ventilation should be ensured when using DMSO to avoid inhaling its vapor. It is best used with an exhaust fan or ventilation system.
3. Light storage: DMSO is sensitive to light, so try to avoid direct sunlight when in use, and storage should also be away from the light source.
4. Fire hazard: DMSO is a flammable liquid, so it should be kept away from open flame and heat source to avoid fire accidents.
5. Avoid mixing: When dealing with DMSO, avoid mixing with strong oxidants, strong acids, strong bases and other substances, so as not to cause dangerous reactions.
6. Medical emergency: In case of accidental contact with skin or eyes, rinse immediately with plenty of water and seek medical attention in time.
In general, when using DMSO, it is necessary to strictly follow safe operating procedures and take the necessary personal protective measures to ensure safe use.
DMSO frequently asked questions
What is the molarity of DMSO?
DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.
What is the DMSO dissolved in?
DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.
Where does DMSO come from?
DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.
What concentration of DMSO do I use in a cell freezing media?
DMSO is usually used at 1-10%, depending on the cell line. For the cell freezing media that we offer, it is used at 8.7% concentration.
Does DMSO have any synthetic utility?
DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
What is the specification for ‘pass’ for cell freezing on the Certificate of Analysis for Dimethyl sulfoxide (DMSO)?
Product D2438 is assessed for cell freezing. Cells are frozen and stored at -70°C. The cells are thawed, cultured and viability is assessed at 24 hours. There is no evidence of cytotoxicity or abnormal cell growth.
Dimethyl sulfoxide (DMSO) should be a liquid. Why did it arrive as a solid?
DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.
What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?
The industry standard for ‘endotoxin free’ is less than 1 EU/mL.
What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?
DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the “Documents” section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product’s (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.