DMSO dimethyl sulfoxide method of use

DMSO is a natural chemical originally found in wood. Over the past 60 years, more than 40,000 articles have been published on this type of DMSO, but the public is not aware of the application of DMSO in medicine and health. Medicine and health refuse to advertise, so unlike ordinary consumer goods, people can be informed about them through advertising. Even in the United States, even complementary foods placed on the open shelves of supermarkets cannot be advertised to spread relevant knowledge. DMSO, approved by the US FDA in 1974, is still only used by a small number of experts and practitioners of alternative medicine and natural medicine in the health and medical fields.

dmso solvent real picture

DMSO has solution and permeability to many drugs, and it also has anti-inflammatory and analgesic effects. DMSO can promote blood circulation and wound healing, and has diuretic and antistatic effects. It can increase drug absorption and improve curative effect, so it is called “universal medicine” in foreign countries. A variety of drugs can be dissolved in DMSO, without oral and injection, applied on the skin can penetrate into the body, opening up a new way of drug delivery. More importantly, it increases the local drug content of the patient and reduces the harm of other drugs in the body. At present, DMSO has been widely used in the external drugs such as Guyouling, beriberi medicine, Fuhydropine ointment and the external preparations of major hospitals.

There are many reports about the use of DMSO in medical research abroad in 1960s. Some foreign studies believe that cancer cells have a cutin protective film, which will hinder the entry of drugs, and DMSO has the ability to dissolve and penetrate diagonal substances, so it can improve the efficacy of tumor.

In China, academic institutions such as Shenyang Pharmaceutical University, Beijing Institute of Pharmaceutical Research, and China Drug Testing Center also carried out comprehensive toxicological tests and pathological anatomical evidence in the 1960s: The LG50 value of the half amount of DMSO in China is (22.4±1.4)g/kg, which is basically consistent with the 21.4g/kg reported in foreign literatures. Therefore, it is determined that DMSO is non-toxic and consistent with the pathological autopsy findings. In the 1960s, 160 medical units such as Peking Union Medical College Hospital conducted clinical trials, and set up special clinics in Benxi, accumulating a large amount of data, which has been proved to be effective in neurodermatitis, psoriasis, arthritis, bursitis, folliculitis, rheumatoid disease, otitis media, rhinitis, adnexitis, toothache, blister, hemorrhoids, sprains, lumbar muscle strain, burns, trauma and so on. At present, the production of Guyouling, beriberi medicine, Fuhydropine ointment and other external drugs and major hospitals have been widely used in the external preparations. The Institute of Veterinary Medicine of the Chinese Academy of Sciences has also used DMSOdissolving “Paz” to treat infectious anemia and parasitic diseases in horses.

In the United States and Europe, DMSO is both used in clinical prescription drugs, and there are various concentrations of “solvents” publicly sold in supermarkets, and consumers can buy them by themselves. More is used for external use, the treatment of osteoarthritis, often received a good effect.

DMSO was discovered by Russian physician Alexander M. Saytzeff in 1866. In the 1950s, British scientists discovered that it could be used as an antifreeze to store bone marrow and blood cells. This unique by-product of the wood pulp industry can also be used as an industrial solvent and paint thinner.

In the late 1950s, the Crown Zellerbach Corporation, one of the world’s largest paper mills, asked its chemist Robert Herschler to find other uses for DMSO. After numerous experiments, Herschel found that DMSO, mixed with certain antibiotics and anti-mildew agents, could penetrate into the plant’s circulatory system. Some chemicals also have this ability, but DMSO is different from other chemicals in that it does not change or damage the protective coating on the outer layer of plant cells.

When Herschel discovered that DMSO might have medical uses, he told his old friend Dr. Stanley Jacob, who was then an associate professor of surgery at the University of Oregon. Jacob specializes in cryobiology, which involves freezing and preserving organs for transplant. Because of his work, he knew that DMSO had antifreeze properties, but he was surprised that DMSO could also penetrate cell membranes, and Jacob was even more surprised that DMSO could also carry certain substances through the skin and into the blood.

Preliminary animal studies have shown very low toxicity of DMSO. He used DMSO on himself and other people, and the results showed that DMSO can quickly relieve pain, stop headaches, and even quickly recover and restore muscle sprains and burns.

A University of Oregon research grant is supporting further human studies, and Herschler is encouraged by the early results.

Crown Zelerbach applied to the Oregon state government for a medicinal patent for DMSO, and the proposed medical use was open to public review.

On December 10, 1963, the local newspaper in Portland, Oregon, listed the functions of DMSO in a front-page story, and called it a miracle cure. But the medical community demanded that these new findings be published first in proper scientific journals, not in the public media.

In 1963, the FDA approved DMSO for human trials, and some big pharmaceutical companies conducted an unprecedented number of experiments, spending a total of 250 million dollars, testing more than 100,000 people, and each group of experiments showed that DMSO was a very safe and effective substance. None of the human trials had a poisoning problem. But a study by Merck, a drug company, showed some cloudy changes in the lens of the eye in some animals receiving DMSO. On December 25, 1965, based on Merck’s research, the FDA banned all human use of DMSO.

But studies of DMSO around the world continue to show its safety. In 1967, the FDA again approved limited human studies. This year, the Vacaville study (detailed below) showed that DMSO use is absolutely harmless to the human eye. Based on this data and other studies, the FDA further expanded the scope of human testing in 1968.

In the meantime, several pharmaceutical companies have applied to the FDA to market DMSO, all of which have been rejected. FDA officials strongly oppose the use of DMSO. They spoke out against the DMSO and its supporters. They insisted that the DMSO should never be marketed. As a result, many pharmaceutical companies stopped their DMSO studies. Unfortunately, of the more than 100,000 cases studied by these pharmaceutical companies, only a few thousand have been published. Still, more than 3,000 published studies have made DMSO potentially one of the safest agents in the history of medicine.

In the mid-1970s, a Utah company finally received FDA approval to market DMSO for the treatment of interstitial cystitis. Medicine and health refuse to advertise, so unlike ordinary consumer goods, people can be informed about them through advertising. Even in the United States, even complementary foods placed on the open shelves of supermarkets cannot be advertised to spread relevant knowledge. DMSO, approved by the US FDA in 1974, is still only used by a small number of experts and practitioners of alternative medicine and natural medicine in the health and medical fields.

A brief history of DMSO

A University of Oregon research grant is supporting further human studies, and Herschler is encouraged by the early results.

Crown Zelerbach applied to the Oregon state government for a medicinal patent for DMSO, and the proposed medical use was open to public review.

In the mid-1970s, a Utah company finally received FDA approval to market DMSO for the treatment of interstitial cystitis.

Biological response of DMSO

Most agents have one or two biological reactions. Some fight infections, others relax muscles, slow the heart rate, remove excess fluid, and so on. No other substance has as many functions as DMSO without causing serious side effects.

1. Penetrate the skin

The most unique aspect of DMSO is its ability to penetrate the skin without damaging or altering the skin’s protective membrane. Alcohol, gasoline, acetone (acetone), and ammonia (amonia) can also penetrate the skin and enter the bloodstream, but can cause serious damage. …

The penetration of DMSO varies from tissue to tissue. The bladder, for example, is easy to penetrate, while bones are more difficult. The concentration of DMSO also affects its penetration. DMSO with a concentration of 90% (containing 10% distilled water) has a faster penetration rate than pure (100%) DMSO. Generally, 70-90% DMSO solution is ideal. Prescription DMSO solutions are available only in 50% and 100% forms.

There has been much misinformation about the ability of DMSO to carry various substances into the skin. For example, some say that low-mass molecules are easier to transport, such as penicillin, steroids, especially hydrocortisone, and mixed with DMSO, penetrate the skin more efficiently. Insulin, bacteria, viruses, etc., are too large to be delivered. In fact, studies have shown that substances that can be delivered by DMSO have the ability to penetrate the skin on their own, but only if the substance is in direct contact with the skin long enough. The properties of DMSO transport materials are often overstated.

2. Relieve pain

Pain can be acute or chronic. Acute pain, such as exercise sprains, can usually be relieved with DMSO within five to 30 minutes. Chronic pain, such as severe arthritis, can take one to six weeks, or even longer.

No topical analgesic is superior to DMSO. It also doesn’t have the narcotic side effects that many analgesics do. An animal study at Emory School of Medicine showed that DMSO was as effective as morphine in relieving pain in mice, but the former lasted seven hours, the latter only two hours.

DMSO is also very safe. Most narcotic analgesics disrupt the patient’s sense of pain; DMSO only removes pain without damaging the pain in the area. DMSO also has no side effects common to other analgesics, such as disorientation, grogginess, constipation, vomiting, nausea, dry mouth, headache, insomnia, heart palpitations, and impotence. Unlike other painkillers, DMSO needs less and less after a period of use.

3, anti-inflammatory

Inflammation is the response of tissues to direct injury (muscle sprain, cuts, burns, vibrations, radiation, etc.) or indirect injury (such as infection). Inflammation involves pain, fever, redness, swelling and loss of function. This is the body’s special way of surrounding the injured area so that it can repair the affected area. DMSO can reduce the severity of inflammation.

DMSO improves blood circulation throughout the body. It seems to dilate large blood vessels and constrict capillary beds. This helps reduce swelling and fluid leakage in the affected area, while increasing the body’s ability to remove toxins and waste from the affected area. DMSO can reduce an injury that takes weeks to recover to a few days.

4, anti-bacterial

DMSO is not a highly effective all-purpose disinfectant, but it has a moderate antibacterial effect. 35% DMSO solution inhibited the growth of a wide range of bacteria and fungi. It can also make certain bacteria more sensitive to antibiotics. One study showed that a 5% solution of DMSO increased the sensitivity of tuberculosis bacteria to streptomycin (TB drug) by 200 times.

5, good urine

On the skin, DMSO has only a slight diuretic effect; But with the right injection, it can be one of the strongest diuretics. In some cases, it increased urine production 10-fold. DMSO’s strong affinity for water puts excess fluid into the bloodstream, where it is filtered out by the kidneys. Severe head and spinal cord injuries can cause brain edema and swelling of brain cells, resulting in increased intracranial pressure and permanent nerve damage. DMSO, as a dehydrating agent and diuretic, may be a lifesaver for such patients.

5. Prevent abnormal collagen

collagen is a type of protein that makes up the association group. Abnormal collagen buildup can lead to arteriosclerosis and arthritis. In some cases, DMSO can soften and even remove abnormal collagen. A rabbit experiment showed that DMSO prevented hardening of the arteries caused by a high-cholesterol diet.

6. Boost your immune system

Studies on the effects of DMSO on immune system and autoimmune diseases are limited. Animal studies have shown that DMSO reduces autoimmune antibodies to myasthenia gravis.

7. Relax your muscles

DMSO improves blood circulation to the muscles and removes toxic substances and metabolic waste that cause muscle cramps. This is great for relieving muscle cramps at night. DMSO does not destroy or numb the central nervous system like other muscle relaxants and can avoid many side effects.

Efficacy of DMSO for various symptoms

1. amyloidosis

Small amounts of amyloid can be found throughout the body. Amyloidosis is the accumulation of amyloid fibers in an organ. Its symptoms vary depending on where and how much it accumulates. It can disrupt the function of the liver, kidneys, spleen, and heart. It can also cause nerve compression and pain in the legs, feet, hands, and arms (similar to the symptoms of carpal tunnel syndrome). Other possible symptoms include intestinal bleeding, irregular heartbeat, skin boils and discoloration.

Alzheimer’s disease, or dementia, is associated with amyloidosis in brain cells. Cerebral amyloid angiopathy is a kind of cerebrovascular disease in the elderly. Its clinical characteristics are dementia, mental symptoms, repeated or multiple lobular hemorrhage.

Human experiments have shown that in all patients treated with DMSO, within 24 hours, the amyloid can be completely excreted in the urine. Patients with either oral or intravenous DMSO were able to break down amyloid tumors.

2. Arthritis

DMSO has been shown to be effective in treating hundreds of types of inflammation and pain caused by arthritis, most of them. Although it is effective for acute and chronic pain, it is more effective for acute pain.

The anti-inflammatory properties of DMSO are the reason why it can be effective in treating arthritis and relieving pain, in addition to some important properties. It cleans up free radicals. Free radicals are harmful substances produced in the body or by factors outside the body. Certain enzymes such as superoxide catalase dismutase(SOD), vitamins A, E, C, etc., are known as free radical scavenger, can convert free radicals into harmless substances. Associated with arthritis are hydroxyl radicals, and DMSO is a powerful hydroxyl radical scavenger.

DMSO prevents free radicals from destroying the lubrication between the joints, and sufficient joint lubrication can relieve the pain and inflammation of acute arthritis. DMSO also improves joint mobility and stabilizes chronic arthritis, and can also reduce the number of autoimmune antibodies that cause tissue damage in rheumatoid arthritis patients.

Studies have shown that the earlier rheumatoid arthritis is treated, the better the response, and the longer the symptoms, the less significant the effect of DMSO. In general, long-term treatment with DMSO coupled with proper nutrition is more effective.

DMSO is highly effective in the treatment of osteoarthritis, regardless of the age, stage and severity of the disease. Large joints such as the femur, knee, and shoulder may require a longer period of treatment. In extreme cases, DMSO injection is more effective than external application.

Numerous trials of DMSO for arthritis have been conducted in the United States and abroad. In the early 1960s, the Rheumatology Society in Japan, the Syntex Laboratories in the United States, and a group of German doctors all conducted similar studies and found that DMSO was effective in treating inflammation and pain in arthritis. Dr. Arthur, of the Sintax lab, also says DMSO can improve joint mobility. After testing DMSO between 1972 and 1978, Russian scientists concluded that “there is sufficient evidence that DMSO can treat inflammatory and degenerative joint diseases.” Patients were able to receive various combinations of therapies, including DMSO, with very few side effects.”

bursitis, diabetes, toothache, ear disease, eye disease, cold shoulder, gout, headache, herpes parthenosus, interstitial cystitis, mental retardation, nasal flesh polyps, neuritis, pain, Parkinson’s disease, periodontal disease, plastic surgery, prophylaxis, psoriasis, pruritus, Raynauld’s disease disease), rhinoscleroma, sinusitis, shingles, muscle sprains, varicose veins.

Special uses of DMSO

1. Cold injury

Animal experiments have shown that applying DMSO before tissue freezing can avoid tissue damage. After the body was frozen for 24 hours, DMSO was applied to show complete recovery, without deterioration or need for amputation.

There was a dramatic case of frostbite in Illinois. A 59-year-old woman slipped outside her home in the middle of the night and was found six hours later. The outside temperature is minus 26 degrees Celsius. The emergency room found that the patient had no sense of direction, could not answer, irregular heartbeat, lower than normal rectal temperature, hands and feet purple, knee, left foot, right bigfoot fingers have ice, the patient has lost sensation in all of the above parts.

After 12 hours, traditional treatments showed no effect. The doctor applied 65% DMSO solution to the affected area, and after only ten minutes, blood circulation improved, and the patient regained consciousness the next day. Over the course of a month, more than a gallon of DMSO solution was used, and the patient returned to normal with no limb damage.

A year later, the woman said that since using DMSO after the fall, the skin on her hands is softer than it was 20 years ago, her hair is thicker and darker, and her nails are less brittle.

2. Radiation damage

Japanese studies have shown that DMSO can protect the skin of patients undergoing radiation therapy, making irradiated skin recover faster.

3. Brain and spinal cord injuries

Dr. Jakob says using DMSO within an hour of a head injury can prevent death or paralysis, based on animal studies and human use.

Most are administered intravenously with 10-40% DMSO solution within one to four hours of an accident. The ability of DMSO to relieve pressure in the skull is unmatched.

The iron and copper in the wound blood will cause free radicals, and DMSO can quickly penetrate the skin, inhibit the formation of these free radicals, and reduce the damage to nerves and surrounding tissues.

Anticancer effect of DMSO

In April 1974, Joseph Floy, the 56-year-old general manager of the Exon Oil industry, was diagnosed with colon-adenocarcinoma due to rectal bleeding. Intestinal adenocarcinoma affects people of all ages, but the older the person, the higher the risk. Usually found in the duodenum and sometimes in the ileum, it causes intestinal obstruction, pain, bleeding, and rapid weight loss. Mr Floy’s cancer has invaded his large intestine. Survival time was determined by the extent of intestinal wall, lymph node metastasis, and the distance of metastasis. Unfortunately, Floy’s cancer had spread to her lymph nodes and metastasized to her liver.

Surgically removed a 13-inch large intestine and abdominal lymph nodes. Dr. Harley advised him to get chemotherapy, because the adenocarcinoma was sure to return in a few months, and the doctor said that his own wife had adenocarcinoma and was undergoing chemotherapy. Mr Floy struggled with this, but in the end he refused chemotherapy. He remembered that two years earlier, he had seen a television report that Dr. E. J. Tucker of Houston had cured cancer, and Mr. Floy was eager to find out. He was discharged from the hospital on Saturday after rectal surgery, and on Monday he and his wife visited Dr. Tucker. After much struggle, “Dr. Tucker agreed to give me an experimental treatment.” ‘said Mr Floy.’ Within six weeks, Dr Harry’s wife died of chemotherapy. But I went back to work and saw Dr. Tucker every two days for treatment. I had no nausea, vomiting or any of the usual side effects of chemotherapy, and about 18 months later, my CEA test was well below normal, and Dr. Tucker declared me cancer-free. Since then, I have been checked every month, and now I am checked every three or four months, and my CEA numbers are always lower than normal.” Mr. Floy’s A.A.G. is down from 18 to zero.

On May 16, 1983, at the age of 65, Mr. Floy had retired and opened a small health food store in a small Texas town. He credits Dr. Tucker for his recovery and survival.

Floy’s treatment was discovered by Dr. Tucker in 1966.

Dmso-hematoxylin animal experiment

Eli Jordon Tucker, Jr., M.D., a 78-year-old plastic surgeon who has practiced in Houston for 52 years, has performed more than 1,000 joint surgeries on a variety of joint patients.

In 1962, Tucker had the idea that there might be so-called cancer antibodies. Scientists were studying interferon, looking for the same thing. In addition to studying bone adhesives for bone grafts, Dr. Tucker conducted another study looking for cancer antibodies in the blood of cows with cancer.

He needed the dye to color the cancer cells so he could watch them change. … hematoxylon turned out to be the perfect dye, which can make cancer cells attach one color and normal cells attach another color, which is a polychromatic dye. … Hematoxylin is also used to treat dysentery and urinary infections.

The disadvantage of using hematoxylin as a tissue dye is that it is a resin and does not dissolve in common laboratory solvents such as alcohol and ether.

In 1963, DMSO was used as a solvent, and Tucker found that it was no longer a problem to dissolve hematoxylin. DMSO not only does not change the characteristics of hematoxylin, but also can transport it to the tumor and stain the cancer cells with a special color.

A dog owned by a friend of Dr. Tucker’s has a giant cell lymphoma, and it’s covered in tumors, and it’s gonna clog its throat. Two weeks after injection with DMSO-hematoxylin solution, the tumor was completely gone. The dog later died of food poisoning, and after autopsy, no active cancer cells were found in the remnants of the tumor.

Another dog with small cell lymphoma was injected with DMSO-hematoxylin, but the effect was not as dramatic and he died two months after stopping treatment.

A wild horse developed bone cancer on the right foreleg. The tumor disappeared after continuous application of a mixture of 25cc DMSO-sapan solution and 500cc ordinary glucose saline for one year.

Anticancer fluid is used for patients at risk

Dr. Bev asked Dr. Tucker to try the DMSO-hematoxylin solution on an inoperable fibrosarcoma patient who was dying. The patient had fallen into a terminal coma, and when her husband heard about Dr. Tucker’s animal experiments, he asked Dr. Tucker to take the plunge.

Sitting at the bedside, Dr. Tucker administered the IV, extremely slowly and carefully, and the first injection took six hours. After a few weeks of treatment, the tumor began to recede and shrink enough to accept surgery, and surgery was performed. The patient was safe and lost contact two years later when he moved.

Dr. Tucker conducted extensive research on a private basis, documenting the effects of the solution on different cancers. … The results of treatment of 37 cases of malignant tumor were analyzed, and DMSO-sapan combined with current anticancer methods could improve 70.5% of patients. These include surgery, radiation and chemotherapy.

The effect of general anticancer therapy alone was 5.4%. With DMSO-hematoxylin solution alone, the yield was 38.1%. …

Most striking were two cases of giant cell lymphoma, where the tumor completely disappeared, and two cases of malignant giant cell bone cancer, where the tumor completely disappeared and new bone grew in one case.

Dmso-hematoxylin solution for the treatment of cancer

In 1968, Dr. Tucker stopped publicly reporting on his research and treatment of cancer, but he did not completely stop treating the few patients who came to him. For example, he cured two patients with giant cell lymphoma, one of whom died of heart disease eight years later and the other is still alive today (14 years later). The latter, Mrs. Wilson, then 38 years old, was diagnosed with adenocarcinoma in January 1972, with large tumors in the lungs, ileum arteries, and lymph nodes surrounding the major arteries. The patient’s small intestine cancer causes long-term nutritional malabsorption, resulting in long-term failure, emaciation, pale mucous membranes, and black dry dander. Abdominal ascites, swelling, severe anemia, cancer cells metastasized to the bone marrow, lymph nodes destroyed. The patient faces death at any time.

Mrs. Wilson received the highest dose of chemotherapy for a month, followed by chemotherapy and radiation for another month, and the tumor continued to spread. Chemotherapy was interrupted because of serious side effects, one of which was that white blood cells had dropped below the limit of 5,000, making them virtually immune.

From January 1973 to January 1974, Dr. Tucker began giving patients DMSO-Hematoxylin solution intravenously, once every two days. Over time, all signs of the tumor completely disappeared, and the patient is still alive today (14 years later) with no side effects.

On January 14, 1970, a 3-year-old boy named Clyde was brought to Dr. Tucker’s office by his mother. The child had diabetes insipidus and was treated at the Children’s Hospital in Houston, Texas. Unfortunately, he developed metastatic endothelioma (Letterer-Siwe disease) and was treated at Anderson Cancer Center. Multiple cancers have spread to the scalp and body, and tumors inside both ears cause draining sinuses. An eye, ear, nose and throat doctor concluded that the disease was incurable, and it was impossible to live beyond the age of 6 or 7. Because of the child’s illness, the father ran away from home, leaving mother and son in poverty. The child’s mother heard about Tucker’s unique treatment and came to see him. Dr. Tucker agreed to treat him free of charge, but stated that it was an experimental treatment and not necessarily effective.

Dr. Tucker gave a small bottle of DMSO-hematoxylin solution and told the mother to take five drops of the solution and distilled water every morning for the child to swallow on an empty stomach. And told her to take the child to the first two hospitals as usual to see a doctor to get medicine, and tell the doctor what medicine the child swallowed.

The next day, the child’s mother came to Dr. Tucker’s clinic, crying and complaining: the doctor at the children’s hospital was furious and told her not to come here if she used Tucker’s medicine. …

Now 17 years old, the child is still taking Dr. Tucker’s cancer drug every day.

Jacob describes DMSO

Dr. Jacob published the efficacy of DMSO (dimethyl sulfoxide) in 1962, and has been studying DMSO for more than 30 years (this book was published in 1993). Dr. Jacob was researching the effects of DMSO on inflammation when the dean of the medical school asked him for some to try for arthritis in his wrist. The results were promising.

Dr. Jacobs told the story of one case: a nine-year-old girl with paralytic arthritis, whose neck arthritis was so severe that she could not turn her chin to her shoulder, and whose right hip was so painful that she could not walk. After applying DMSO to her skin for an hour, the girl was able to slowly turn her chin toward her shoulders, but when asked to walk, she refused because it was too painful. Finally, when she was willing to try it out, she burst into tears. When Dr. Jacob asked her why she was crying, she sobbed: Because the pain was gone.

DMSO is also effective in Scleroderma. Dr Jacob, who is one of the national advisers of the International Scleroderma Foundation, said that although DMSO is underused, it is an alternative treatment for scleroderma and Raynaud’s phenomenon, and is also effective for rheumatoid arthritis. At the scleroderma Foundation annual meeting, he could not find a single scleroderma patient who had been treated effectively with a therapy other than DMSO.

DMSO is also a powerful free radical purifier – especially for Alzheimer’s patients. Dr. Jacob says DMSO could be an effective treatment for Alzheimer’s disease. He pointed out that an effective dementia treatment should have three functions:

It is easy to cross the blood-brain barrier and enter brain cells

Second, powerful free radical scavenger

Dissolve amyloid, an abnormal mucin that typically accumulates in the brain cells of people with dementia.

Some preliminary studies have shown that DMSO is effective. When DMSO and other substances were injected intravenously into patients, 70 percent showed a 25 percent improvement in short-term memory within three months. This is remarkable because the natural improvement of Alzheimer’s never occurred; dementia always progressed.

Safety of DMSO

DMSO has two common side effects, one is the smell of garlic or oyster, and the other is a slight redness, irritation and other reactions on the skin where it is applied, and the skin reaction is gradually reduced after multiple applications.

Repeated studies have shown that external application of DMSO does not cause serious side effects. In fact, not a single study or trial has shown that DMSO is toxic. On 31 July 1980, Dr. Jakob made the following statement to the United States Senate Committee on Health Care:

“The big problem with drugs is toxicity. There is no such thing as a non-toxic agent. DMSO has its side effects. The main side effect is that some patients may develop allergies. I believe that there is more information on the toxicity of DMSO to animals than there is available experimental data on other agents. I haven’t seen anything safer (than DMSO). In my estimation, no other agent has more experimental data on human toxicity than DMSO. The Food and Drug Administration (FDA) alone has more than 100,000 medical records. Despite the use of DMSO as a prescription around the world, I am not aware of any well-documented cases of poisoning. ”

The use of DMSO

DMSO is safe and easy to use. The side effects of DMSO are occasional nausea, skin irritation, and a garlic-like smell emanating from the skin and breath, which disappears after about eight hours. There are four types of ingestion: intravenous, subcutaneous, oral and topical. Oral and intravenous injections are most effective.

It is suitable for patients with arthritis and Alzheimer’s disease. Gastrointestinal tumors are suitable for intravenous administration.

For the first time, prepare 25% DMSO solution (that is, add 75% distilled water), apply a small amount on the arm, wait 15 to 20 minutes, if the skin reaction is slight, can be changed to 50%, 75%, or even 90%. Test on different parts, if the reaction is abnormal, can be washed over the smears, and then apply with general skin care cream.

Step 1 Apply externally

Apply to affected area and surrounding area. Use finger, cotton ball, sponge (swab) lightly. (Rubbing hard will increase the skin’s irritating response and prolong the absorption time). Textiles made of rayon, acrylic or other synthetic materials are easily decomposed and dissolved in DMSO.

DMSO applied on the skin, within 15 minutes will be absorbed, the application of the part, the skin hole to remain “open” for about half an hour, based on safety considerations, the application of DMSO part of the best three hours to avoid direct contact with pesticides, paint, bleaching, hair dye, deodorant, cosmetics and even newspaper. If unlucky to touch the above substances, wash with water and soap.

It is recommended to wash the skin before application, which is not necessary, and wet skin will reduce the purity of DMSO, so you should avoid bathing or swimming 30 minutes before and after applying DMSO.

One of the chemical properties of DMSO is that it destroys dangerous free radicals and converts itself into less harmful free radicals. To help neutralize these “by-products,” it is recommended to take vitamins and minerals with antioxidant properties. When using DMSO, A multivitamin containing vitamins A, C, E, B1, B6, cysteine, zinc, and selenium should be taken.

Usage: 15~15cc each time.

Number of times: Acute symptoms start quickly but do not recur, such as ankle sprains, dark circles under the eyes, frostbite, burns, etc. Chronic disease refers to long-term recurrent, not subsiding, such as arthritis, gout, peripheral circulation disease.

Acute symptoms should be applied every two hours for six to eight hours, followed by every four to six hours for five days.

Chronic symptoms require a longer treatment period. In most cases, some degree of improvement can be felt within the first week, but some studies indicate that it may take 6 to 8 weeks to see significant changes. To achieve maximum results, it may take six months to a year of treatment.

Chronic symptoms are usually given daily until the symptoms resolve. Since then, because DMSO has a “residual effect”, it can be applied once or twice a week. However, people have individual differences and should be adjusted according to the needs of users. It is generally believed that the drug is given for one month and discontinued for one month. Others suggest giving the drug for five days, stopping for two days, and then stopping for two to four weeks every six months.

2. Oral clothing

In the early days, many people take one or two teaspoons of DMSO and juice before bed to treat chronic diseases (intellectual disability, arthritis, scleroderma, etc.). DMSO can penetrate the whole body from the skin, and oral administration will reduce stomach acid and affect the absorption of food nutrients, so oral administration is no longer recommended. But it is still used by a small number of people.

3. Intravenous injection

This can only be briefly described. This method is mainly used for severe craniocerebral injury and spinal cord injury. It is usually 10-20% DMSO solution. A solution of more than 50% purity will break down the red blood cells at the injection site. Intravenous DMSO is generally considered to be an effective treatment for the control of intracranial hydrops and intracranial pressure.

DMSO dimethyl sulfoxide method of use

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