{"id":474,"date":"2023-12-25T15:58:15","date_gmt":"2023-12-25T07:58:15","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=474"},"modified":"2024-02-02T16:28:01","modified_gmt":"2024-02-02T08:28:01","slug":"dmso-dimethyl-sulfoxide-method-of-use","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/dmso-dimethyl-sulfoxide-method-of-use\/","title":{"rendered":"DMSO \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc \uc0ac\uc6a9 \ubc29\ubc95"},"content":{"rendered":"

DMSO\ub294 \uc6d0\ub798 \ubaa9\uc7ac\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 \ucc9c\uc5f0 \ud654\ud559\ubb3c\uc9c8\uc785\ub2c8\ub2e4. \uc9c0\ub09c 60\ub144 \ub3d9\uc548 \uc774\ub7ec\ud55c \uc720\ud615\uc758 DMSO\uc5d0 \uad00\ud574 40,000\uac1c \uc774\uc0c1\uc758 \uae30\uc0ac\uac00 \ucd9c\ud310\ub418\uc5c8\uc9c0\ub9cc \ub300\uc911\uc740 DMSO\uac00 \uc758\ud559 \ubc0f \uac74\uac15\uc5d0 \uc801\uc6a9\ub418\ub294 \uac83\uc744 \uc778\uc2dd\ud558\uc9c0 \ubabb\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc758\ud559\uacfc \uac74\uac15\uc740 \uad11\uace0\ub97c \uac70\ubd80\ud558\ubbc0\ub85c \uc77c\ubc18 \uc18c\ube44\uc7ac\uc640 \ub2ec\ub9ac \uad11\uace0\ub97c \ud1b5\ud574 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc54c\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d\uc5d0\uc11c\ub3c4 \uc288\ud37c\ub9c8\ucf13\uc758 \uc9c4\uc5f4\ub300\uc5d0 \ub193\uc5ec \uc788\ub294 \ubcf4\uc644\uc2dd\ud488\uc774\ub77c\ub3c4 \uad00\ub828 \uc9c0\uc2dd\uc744 \uc804\ud30c\ud558\uae30 \uc704\ud55c \uad11\uace0\ub97c \ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. 1974\ub144 \ubbf8\uad6d FDA\uc758 \uc2b9\uc778\uc744 \ubc1b\uc740 DMSO\ub294 \uc5ec\uc804\ud788 \ubcf4\uac74 \ubc0f \uc758\ub8cc \ubd84\uc57c\uc758 \ub300\uccb4 \uc758\ud559 \ubc0f \uc790\uc5f0 \uc758\ud559 \uc804\ubb38\uac00\uc640 \uc2e4\ubb34\uc790\uc5d0 \uc758\ud574\uc11c\ub9cc \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\"dmso<\/p>\n

DMSO\ub294 \ub9ce\uc740 \uc57d\ubb3c\uc5d0 \ub300\ud55c \uc6a9\ud574\uc131\uacfc \ud22c\uacfc\uc131\uc744 \uac16\uace0 \uc788\uc73c\uba70, \ud56d\uc5fc\uc99d, \uc9c4\ud1b5 \ud6a8\uacfc\ub3c4 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ud608\uc561\uc21c\ud658\uacfc \uc0c1\ucc98 \uce58\uc720\ub97c \ucd09\uc9c4\ud560 \uc218 \uc788\uc73c\uba70 \uc774\ub1e8 \ubc0f \uc815\uc804\uae30 \ubc29\uc9c0 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc57d\ubb3c\uc758 \ud761\uc218\ub97c \ub192\uc774\uace0 \uce58\ub8cc \ud6a8\uacfc\ub97c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc5b4 \uc678\uad6d\uc5d0\uc11c\ub294 '\ub9cc\ub2a5\uc758\ud559'\uc73c\ub85c \ubd88\ub9b0\ub2e4. \ub2e4\uc591\ud55c \uc57d\ubb3c\uc744 \uacbd\uad6c\ub098 \uc8fc\uc0ac \uc5c6\uc774 DMSO\uc5d0 \uc6a9\ud574\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \ud53c\ubd80\uc5d0 \ubc14\ub974\uba74 \uccb4\ub0b4\ub85c \uce68\ud22c\ud558\uc5ec \uc57d\ubb3c \uc804\ub2ec\uc758 \uc0c8\ub85c\uc6b4 \uae38\uc744 \uc5f4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub354 \uc911\uc694\ud55c \uac83\uc740 \ud658\uc790\uc758 \uad6d\uc18c \uc57d\ubb3c \ud568\ub7c9\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \uc2e0\uccb4 \ub0b4 \ub2e4\ub978 \uc57d\ubb3c\uc758 \uc720\ud574\uc131\uc744 \uac10\uc18c\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ud604\uc7ac DMSO\ub294 Guyouling, \uac01\uae30\ubcd1, Fuhydropine \uc5f0\uace0 \ub4f1 \uc678\uc6a9\uc57d\ud488\uacfc \uc8fc\uc694 \ubcd1\uc6d0\uc758 \uc678\uc6a9\uc57d\ud488\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1960\ub144\ub300 \ud574\uc678 \uc758\ud559 \uc5f0\uad6c\uc5d0\uc11c DMSO\ub97c \ud65c\uc6a9\ud588\ub2e4\ub294 \ubcf4\uace0\uac00 \ub9ce\uc774 \uc788\ub2e4. \uc77c\ubd80 \ud574\uc678 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc554\uc138\ud3ec\uc5d0 \ud050\ud2f4 \ubcf4\ud638\ub9c9\uc774 \uc788\uc5b4 \uc57d\ubb3c\uc758 \uc9c4\uc785\uc744 \ubc29\ud574\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uace0 \uc788\uc73c\uba70, DMSO\ub294 \ub300\uac01\uc120 \ubb3c\uc9c8\uc744 \uc6a9\ud574\ud558\uace0 \uce68\ud22c\ud558\ub294 \ub2a5\ub825\uc774 \uc788\uc5b4 \uc885\uc591\uc758 \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\ub2e4\uace0 \ubcf4\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc911\uad6d\uc5d0\uc11c\ub294 1960\ub144\ub300 \uc2ec\uc591\uc57d\uacfc\ub300\ud559, \ubd81\uacbd\uc57d\ud559\uc5f0\uad6c\uc18c, \uc911\uad6d\uc57d\ubb3c\uac80\uc0ac\uc13c\ud130 \ub4f1 \ud559\uc220\uae30\uad00\uc5d0\uc11c\ub3c4 \uc885\ud569\uc801\uc778 \ub3c5\uc131\uc2dc\ud5d8\uacfc \ubcd1\ub9ac\ud574\ubd80\ud559\uc801 \uc99d\uac70\ub97c \uc2e4\uc2dc\ud588\ub2e4. \uc911\uad6d\uc758 DMSO \uc808\ubc18\ub7c9\uc5d0 \ud574\ub2f9\ud558\ub294 LG50 \uac12\uc740 (22.4)\uc774\ub2e4. \u00b11.4)g\/kg\uc73c\ub85c, \uc774\ub294 \ud574\uc678 \ubb38\ud5cc\uc5d0 \ubcf4\uace0\ub41c 21.4g\/kg\uacfc \uae30\ubcf8\uc801\uc73c\ub85c \uc77c\uce58\ud55c\ub2e4. \ub530\ub77c\uc11c DMSO\ub294 \ubb34\ub3c5\uc131\uc774\uba70 \ubcd1\ub9ac\ud559\uc801 \ubd80\uac80 \uc18c\uacac\uacfc \uc77c\uce58\ud558\ub294 \uac83\uc73c\ub85c \ud310\ub2e8\ub41c\ub2e4. 1960\ub144\ub300 \ubd81\uacbd\uc5f0\ud569\uc758\uacfc\ub300\ud559\ubcd1\uc6d0 \ub4f1 160\uac1c \uc758\ub8cc\uae30\uad00\uc5d0\uc11c \uc784\uc0c1\uc2dc\ud5d8\uc744 \uc2e4\uc2dc\ud558\uace0 \ubc88\uc2dc(\u672c\u6eaa)\uc5d0 \uc804\ubb38\uc9c4\ub8cc\uc18c\ub97c \uc124\ub9bd\ud574 \ub9ce\uc740 \uc591\uc758 \ub370\uc774\ud130\ub97c \ucd95\uc801\ud588\ub294\ub370, \uc774\ub294 \uc2e0\uacbd\ud53c\ubd80\uc5fc, \uac74\uc120, \uad00\uc808\uc5fc, \ud65c\uc561\ub0ad\uc5fc, \ubaa8\ub0ad\uc5fc\uc5d0 \ud6a8\uacfc\uac00 \uc788\uc74c\uc774 \uc785\uc99d\ub410\ub2e4. , \ub958\ub9c8\ud2f0\uc2a4 \uc9c8\ud658, \uc911\uc774\uc5fc, \ube44\uc5fc, \ubd80\uc18d\uae30\uc5fc, \uce58\ud1b5, \uc218\ud3ec, \uce58\uc9c8, \uc5fc\uc88c, \uc694\ucd94 \uadfc\uc721 \uae34\uc7a5, \ud654\uc0c1, \uc678\uc0c1 \ub4f1. \ud604\uc7ac \uc678\uc6a9\uc81c\ub85c\ub294 \uae30\uc5ec\ub9c1, \uac01\uae30\uc57d, \ud478\ud788\ub4dc\ub85c\ud540 \uc5f0\uace0 \ub4f1 \uc678\uc6a9\uc57d\ud488\uacfc \ub300\ud615\ubcd1\uc6d0\uc758 \uc0dd\uc0b0\uc774 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\ub2e4. \uc911\uad6d\uacfc\ud559\uc6d0 \uc218\uc758\ud559 \uc5f0\uad6c\uc18c\uc5d0\uc11c\ub294 DMSO\uc6a9\ud574\uc131 \"Paz\"\ub97c \uc0ac\uc6a9\ud558\uc5ec \ub9d0\uc758 \uac10\uc5fc\uc131 \ube48\ud608 \ubc0f \uae30\uc0dd\ucda9 \uc9c8\ud658\uc744 \uce58\ub8cc\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubbf8\uad6d\uacfc \uc720\ub7fd\uc5d0\uc11c\ub294 DMSO\uac00 \uc784\uc0c1 \ucc98\ubc29\uc57d\uc5d0 \ubaa8\ub450 \uc0ac\uc6a9\ub418\uba70 \uc288\ud37c\ub9c8\ucf13\uc5d0\uc11c \uacf5\uac1c\uc801\uc73c\ub85c \ud310\ub9e4\ub418\ub294 \ub2e4\uc591\ud55c \ub18d\ub3c4\uc758 \"\uc6a9\ub9e4\"\uac00 \uc788\uc73c\uba70 \uc18c\ube44\uc790\uac00 \uc9c1\uc811 \uad6c\uc785\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc678\uc6a9\uc73c\ub85c \uc0ac\uc6a9\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc544 \uace8\uad00\uc808\uc5fc \uce58\ub8cc\uc5d0 \uc88b\uc740 \ud6a8\uacfc\ub97c \ubc1b\ub294 \uacbd\uc6b0\uac00 \ub9ce\ub2e4.<\/p>\n

DMSO\ub294 \uc6d0\ub798 \ubaa9\uc7ac\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 \ucc9c\uc5f0 \ud654\ud559\ubb3c\uc9c8\uc785\ub2c8\ub2e4. \uc9c0\ub09c 60\ub144 \ub3d9\uc548 \uc774\ub7ec\ud55c \uc720\ud615\uc758 DMSO\uc5d0 \uad00\ud574 40,000\uac1c \uc774\uc0c1\uc758 \uae30\uc0ac\uac00 \ucd9c\ud310\ub418\uc5c8\uc9c0\ub9cc \ub300\uc911\uc740 DMSO\uac00 \uc758\ud559 \ubc0f \uac74\uac15\uc5d0 \uc801\uc6a9\ub418\ub294 \uac83\uc744 \uc54c\uc9c0 \ubabb\ud569\ub2c8\ub2e4. DMSO\uc758 \uac04\ub7b5\ud55c \uc5ed\uc0ac<\/p>\n

DMSO\ub294 1866\ub144 \ub7ec\uc2dc\uc544 \uc758\uc0ac Alexander M. Saytzeff\uc5d0 \uc758\ud574 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 1950\ub144\ub300 \uc601\uad6d \uacfc\ud559\uc790\ub4e4\uc740 DMSO\uac00 \uace8\uc218\uc640 \ud608\uc561 \uc138\ud3ec\ub97c \uc800\uc7a5\ud558\ub294 \ubd80\ub3d9\uc561\uc73c\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \ubaa9\uc7ac \ud384\ud504 \uc0b0\uc5c5\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \uc774 \ub3c5\ud2b9\ud55c \ubd80\uc0b0\ubb3c\uc740 \uc0b0\uc5c5\uc6a9 \uc6a9\uc81c \ubc0f \ud398\uc778\ud2b8 \ud76c\uc11d\uc81c\ub85c\ub3c4 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1950\ub144\ub300 \ud6c4\ubc18, \uc138\uacc4 \ucd5c\ub300\uc758 \uc81c\uc9c0 \uacf5\uc7a5 \uc911 \ud558\ub098\uc778 Crown Zellerbach Corporation\uc740 \ud654\ud559\uc790 Robert Herschler\uc5d0\uac8c DMSO\uc758 \ub2e4\ub978 \uc6a9\ub3c4\ub97c \ucc3e\uc544\ub2ec\ub77c\uace0 \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4. \uc218\ub9ce\uc740 \uc2e4\ud5d8 \ub05d\uc5d0 Herschel\uc740 \ud2b9\uc815 \ud56d\uc0dd\uc81c \ubc0f \ud56d\uacf0\ud321\uc774\uc81c\uc640 \ud63c\ud569\ub41c DMSO\uac00 \uc2dd\ubb3c\uc758 \uc21c\ud658\uacc4\uc5d0 \uce68\ud22c\ud560 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \ud654\ud559\ubb3c\uc9c8\uc5d0\ub3c4 \uc774\ub7ec\ud55c \ub2a5\ub825\uc774 \uc788\uc9c0\ub9cc DMSO\ub294 \uc2dd\ubb3c \uc138\ud3ec \uc678\uce35\uc758 \ubcf4\ud638 \ucf54\ud305\uc744 \ubcc0\uacbd\ud558\uac70\ub098 \uc190\uc0c1\uc2dc\ud0a4\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc810\uc5d0\uc11c \ub2e4\ub978 \ud654\ud559\ubb3c\uc9c8\uacfc \ub2e4\ub985\ub2c8\ub2e4.<\/p>\n

Herschel\uc740 DMSO\uac00 \uc758\ud559\uc801 \uc6a9\ub3c4\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc744 \ub54c \ub2f9\uc2dc \uc624\ub808\uace4 \ub300\ud559\uc758 \uc678\uacfc \ubd80\uad50\uc218\uc600\ub358 \uc624\ub79c \uce5c\uad6c Stanley Jacob \ubc15\uc0ac\uc5d0\uac8c \ub9d0\ud588\uc2b5\ub2c8\ub2e4. Jacob\uc740 \uc774\uc2dd\uc6a9 \uc7a5\uae30\ub97c \ub0c9\ub3d9\ud558\uace0 \ubcf4\uc874\ud558\ub294 \ub0c9\ub3d9\uc0dd\ubb3c\ud559\uc744 \uc804\ubb38\uc73c\ub85c \ud569\ub2c8\ub2e4. \uadf8\uc758 \uc5f0\uad6c\ub85c \uc778\ud574 \uadf8\ub294 DMSO\uc5d0 \ubd80\ub3d9\uc561 \ud2b9\uc131\uc774 \uc788\ub2e4\ub294 \uac83\uc744 \uc54c\uace0 \uc788\uc5c8\uc9c0\ub9cc DMSO\uac00 \uc138\ud3ec\ub9c9\uc5d0\ub3c4 \uce68\ud22c\ud560 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc5d0 \ub180\ub790\uace0 Jacob\uc740 DMSO\uac00 \ud2b9\uc815 \ubb3c\uc9c8\uc744 \ud53c\ubd80\ub97c \ud1b5\ud574 \ud608\uc561\uc73c\ub85c \uc6b4\ubc18\ud560 \uc218\ub3c4 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc5d0 \ub354\uc6b1 \ub180\ub790\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc608\ube44 \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c\ub294 DMSO\uc758 \ub3c5\uc131\uc774 \ub9e4\uc6b0 \ub0ae\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \uc790\uc2e0\uacfc \ub2e4\ub978 \uc0ac\ub78c\ub4e4\uc5d0\uac8c DMSO\ub97c \uc0ac\uc6a9\ud588\uace0, \uadf8 \uacb0\uacfc DMSO\uac00 \uc2e0\uc18d\ud558\uac8c \ud1b5\uc99d\uc744 \uc644\ud654\ud558\uace0 \ub450\ud1b5\uc744 \uba48\ucd94\uba70 \uc2ec\uc9c0\uc5b4 \uadfc\uc721 \uc5fc\uc88c\uc640 \ud654\uc0c1\uc744 \ube60\ub974\uac8c \ud68c\ubcf5\ud558\uace0 \ud68c\ubcf5\ud560 \uc218 \uc788\uc74c\uc774 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc624\ub808\uace4 \ub300\ud559\uad50 \uc5f0\uad6c \ubcf4\uc870\uae08\uc740 \ucd94\uac00\uc801\uc778 \uc778\uac04 \uc5f0\uad6c\ub97c \uc9c0\uc6d0\ud558\uace0 \uc788\uc73c\uba70 Herschler\ub294 \ucd08\uae30 \uacb0\uacfc\uc5d0 \uace0\ubb34\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

Crown Zelerbach\ub294 DMSO\uc5d0 \ub300\ud55c \uc758\uc57d \ud2b9\ud5c8\ub97c \uc624\ub808\uace4 \uc8fc \uc815\ubd80\uc5d0 \uc2e0\uccad\ud588\uc73c\uba70 \uc81c\uc548\ub41c \uc758\ud559\uc801 \uc6a9\ub3c4\ub294 \uacf5\uac1c \uac80\ud1a0\ub97c \uc704\ud574 \uacf5\uac1c\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

1963\ub144 12\uc6d4 10\uc77c, \uc624\ub808\uace4\uc8fc \ud3ec\ud2c0\ub79c\ub4dc \uc9c0\uc5ed \uc2e0\ubb38\uc740 DMSO\uc758 \uae30\ub2a5\uc744 1\uba74 \uae30\uc0ac\uc5d0 \uae30\uc7ac\ud558\uace0 \uc774\ub97c \uae30\uc801\uc758 \uce58\ub8cc\ubc95\uc774\ub77c\uace0 \ubd88\ub800\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc758\ud559\uacc4\uc5d0\uc11c\ub294 \uc774\ub7ec\ud55c \uc0c8\ub85c\uc6b4 \uc5f0\uad6c \uacb0\uacfc\ub97c \ub300\uc911 \ub9e4\uccb4\uac00 \uc544\ub2cc \uc801\uc808\ud55c \uacfc\ud559 \uc800\ub110\uc5d0 \uba3c\uc800 \ubc1c\ud45c\ud560 \uac83\uc744 \uc694\uad6c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

1963\ub144 FDA\ub294 DMSO\ub97c \uc778\uccb4 \uc2e4\ud5d8\uc6a9\uc73c\ub85c \uc2b9\uc778\ud588\uc73c\uba70, \uc77c\ubd80 \ub300\ud615 \uc81c\uc57d\ud68c\uc0ac\ub294 \ucd1d 2\uc5b5 5\ucc9c\ub9cc \ub2ec\ub7ec\ub97c \uc9c0\ucd9c\ud558\uace0 10\ub9cc \uba85 \uc774\uc0c1\uc744 \ub300\uc0c1\uc73c\ub85c \ud14c\uc2a4\ud2b8\ud558\ub294 \ub4f1 \uc804\ub840 \uc5c6\ub294 \uc218\uc758 \uc2e4\ud5d8\uc744 \uc218\ud589\ud588\uc73c\uba70, \uac01 \uc2e4\ud5d8 \uadf8\ub8f9\uc5d0\uc11c DMSO\uac00 \ub9e4\uc6b0 \uc548\uc804\ud558\uace0 \uc548\uc804\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc774 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud6a8\uacfc\uc801\uc778 \ubb3c\uc9c8. \uc778\uac04\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc2e4\ud5d8\uc5d0\ub294 \uc911\ub3c5 \ubb38\uc81c\uac00 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc81c\uc57d\ud68c\uc0ac\uc778 Merck\uc758 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\ub97c \ud22c\uc5ec\ubc1b\uc740 \uc77c\ubd80 \ub3d9\ubb3c\uc758 \ub208 \uc218\uc815\uccb4\uc5d0 \uc57d\uac04\uc758 \ud63c\ud0c1\ud55c \ubcc0\ud654\uac00 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. 1965\ub144 12\uc6d4 25\uc77c, \uba38\ud06c\uc758 \uc5f0\uad6c\uc5d0 \uae30\ucd08\ud558\uc5ec FDA\ub294 DMSO\uc758 \ubaa8\ub4e0 \uc778\uac04 \uc0ac\uc6a9\uc744 \uae08\uc9c0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc804 \uc138\uacc4\uc801\uc73c\ub85c DMSO\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \uacc4\uc18d\ud574\uc11c \uadf8 \uc548\uc804\uc131\uc744 \uc785\uc99d\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 1967\ub144\uc5d0 FDA\ub294 \uc81c\ud55c\ub41c \uc778\uac04 \uc5f0\uad6c\ub97c \ub2e4\uc2dc \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc62c\ud574 Vacaville \uc5f0\uad6c(\uc544\ub798 \uc790\uc138\ud788 \uc124\uba85)\uc5d0\uc11c\ub294 DMSO \uc0ac\uc6a9\uc774 \uc778\uac04\uc758 \ub208\uc5d0 \uc804\ud600 \ubb34\ud574\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. \uc774 \ub370\uc774\ud130\uc640 \uae30\ud0c0 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c FDA\ub294 1968\ub144\uc5d0 \uc778\uccb4 \ud14c\uc2a4\ud2b8 \ubc94\uc704\ub97c \ub354\uc6b1 \ud655\ub300\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub3d9\uc548 \uc5ec\ub7ec \uc81c\uc57d\ud68c\uc0ac\uac00 DMSO \uc2dc\ud310\uc744 FDA\uc5d0 \uc2e0\uccad\ud588\uc9c0\ub9cc \ubaa8\ub450 \uac70\uc808\ub2f9\ud588\uc2b5\ub2c8\ub2e4. FDA \uad00\uacc4\uc790\ub294 DMSO \uc0ac\uc6a9\uc744 \uac15\ub825\ud788 \ubc18\ub300\ud569\ub2c8\ub2e4. \uadf8\ub4e4\uc740 DMSO\uc640 \uadf8 \uc9c0\uc9c0\uc790\ub4e4\uc744 \ubc18\ub300\ud558\ub294 \ubaa9\uc18c\ub9ac\ub97c \ub0c8\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 DMSO\uac00 \uacb0\ucf54 \uc2dc\uc7a5\uc5d0 \ucd9c\uc2dc\ub418\uc5b4\uc11c\ub294 \uc548 \ub41c\ub2e4\uace0 \uc8fc\uc7a5\ud588\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc \ub9ce\uc740 \uc81c\uc57d\ud68c\uc0ac\ub4e4\uc774 DMSO \uc5f0\uad6c\ub97c \uc911\ub2e8\ud588\uc2b5\ub2c8\ub2e4. \ubd88\ud589\ud558\uac8c\ub3c4 \uc774\ub4e4 \uc81c\uc57d\ud68c\uc0ac\uac00 \uc5f0\uad6c\ud55c 100,000\uac74 \uc774\uc0c1\uc758 \uc0ac\ub840 \uc911 \uacf5\uac1c\ub41c \uc0ac\ub840\ub294 \ubd88\uacfc \uba87 \ucc9c \uac74\uc5d0 \ubd88\uacfc\ud569\ub2c8\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 3,000\uac1c \uc774\uc0c1\uc758 \ubc1c\ud45c\ub41c \uc5f0\uad6c\uc5d0\uc11c DMSO\ub294 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc758\ud559 \uc5ed\uc0ac\uc0c1 \uac00\uc7a5 \uc548\uc804\ud55c \uc57d\ubb3c \uc911 \ud558\ub098\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

1970\ub144\ub300 \uc911\ubc18, \uc720\ud0c0\uc758 \ud55c \ud68c\uc0ac\ub294 \ub9c8\uce68\ub0b4 \uac04\uc9c8\uc131 \ubc29\uad11\uc5fc \uce58\ub8cc\ub97c \uc704\ud574 DMSO\ub97c \uc2dc\ud310\ud558\uae30 \uc704\ud55c FDA \uc2b9\uc778\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc758\ud559\uacfc \uac74\uac15\uc740 \uad11\uace0\ub97c \uac70\ubd80\ud558\ubbc0\ub85c \uc77c\ubc18 \uc18c\ube44\uc7ac\uc640 \ub2ec\ub9ac \uad11\uace0\ub97c \ud1b5\ud574 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc54c\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d\uc5d0\uc11c\ub3c4 \uc288\ud37c\ub9c8\ucf13\uc758 \uc9c4\uc5f4\ub300\uc5d0 \ub193\uc5ec \uc788\ub294 \ubcf4\uc644\uc2dd\ud488\uc774\ub77c\ub3c4 \uad00\ub828 \uc9c0\uc2dd\uc744 \uc804\ud30c\ud558\uae30 \uc704\ud55c \uad11\uace0\ub97c \ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. 1974\ub144 \ubbf8\uad6d FDA\uc758 \uc2b9\uc778\uc744 \ubc1b\uc740 DMSO\ub294 \uc5ec\uc804\ud788 \ubcf4\uac74 \ubc0f \uc758\ub8cc \ubd84\uc57c\uc758 \ub300\uccb4 \uc758\ud559 \ubc0f \uc790\uc5f0 \uc758\ud559 \uc804\ubb38\uac00\uc640 \uc2e4\ubb34\uc790\uc5d0 \uc758\ud574\uc11c\ub9cc \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ub9ce\uc740 \uc57d\ubb3c\uc5d0 \ub300\ud55c \uc6a9\ud574\uc131\uacfc \ud22c\uacfc\uc131\uc744 \uac16\uace0 \uc788\uc73c\uba70, \ud56d\uc5fc\uc99d, \uc9c4\ud1b5 \ud6a8\uacfc\ub3c4 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ud608\uc561\uc21c\ud658\uacfc \uc0c1\ucc98 \uce58\uc720\ub97c \ucd09\uc9c4\ud560 \uc218 \uc788\uc73c\uba70 \uc774\ub1e8 \ubc0f \uc815\uc804\uae30 \ubc29\uc9c0 \ud6a8\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc57d\ubb3c\uc758 \ud761\uc218\ub97c \ub192\uc774\uace0 \uce58\ub8cc \ud6a8\uacfc\ub97c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc5b4 \uc678\uad6d\uc5d0\uc11c\ub294 '\ub9cc\ub2a5\uc758\ud559'\uc73c\ub85c \ubd88\ub9b0\ub2e4. \ub2e4\uc591\ud55c \uc57d\ubb3c\uc744 \uacbd\uad6c\ub098 \uc8fc\uc0ac \uc5c6\uc774 DMSO\uc5d0 \uc6a9\ud574\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \ud53c\ubd80\uc5d0 \ubc14\ub974\uba74 \uccb4\ub0b4\ub85c \uce68\ud22c\ud558\uc5ec \uc57d\ubb3c \uc804\ub2ec\uc758 \uc0c8\ub85c\uc6b4 \uae38\uc744 \uc5f4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub354 \uc911\uc694\ud55c \uac83\uc740 \ud658\uc790\uc758 \uad6d\uc18c \uc57d\ubb3c \ud568\ub7c9\uc744 \uc99d\uac00\uc2dc\ud0a4\uace0 \uc2e0\uccb4 \ub0b4 \ub2e4\ub978 \uc57d\ubb3c\uc758 \uc720\ud574\uc131\uc744 \uac10\uc18c\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ud604\uc7ac DMSO\ub294 Guyouling, \uac01\uae30\ubcd1, Fuhydropine \uc5f0\uace0 \ub4f1 \uc678\uc6a9\uc57d\ud488\uacfc \uc8fc\uc694 \ubcd1\uc6d0\uc758 \uc678\uc6a9\uc57d\ud488\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1960\ub144\ub300 \ud574\uc678 \uc758\ud559 \uc5f0\uad6c\uc5d0\uc11c DMSO\ub97c \ud65c\uc6a9\ud588\ub2e4\ub294 \ubcf4\uace0\uac00 \ub9ce\uc774 \uc788\ub2e4. \uc77c\ubd80 \ud574\uc678 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc554\uc138\ud3ec\uc5d0 \ud050\ud2f4 \ubcf4\ud638\ub9c9\uc774 \uc788\uc5b4 \uc57d\ubb3c\uc758 \uc9c4\uc785\uc744 \ubc29\ud574\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uace0 \uc788\uc73c\uba70, DMSO\ub294 \ub300\uac01\uc120 \ubb3c\uc9c8\uc744 \uc6a9\ud574\ud558\uace0 \uce68\ud22c\ud558\ub294 \ub2a5\ub825\uc774 \uc788\uc5b4 \uc885\uc591\uc758 \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\ub2e4\uace0 \ubcf4\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc911\uad6d\uc5d0\uc11c\ub294 1960\ub144\ub300 \uc2ec\uc591\uc57d\uacfc\ub300\ud559, \ubd81\uacbd\uc57d\ud559\uc5f0\uad6c\uc18c, \uc911\uad6d\uc57d\ubb3c\uac80\uc0ac\uc13c\ud130 \ub4f1 \ud559\uc220\uae30\uad00\uc5d0\uc11c\ub3c4 \uc885\ud569\uc801\uc778 \ub3c5\uc131\uc2dc\ud5d8\uacfc \ubcd1\ub9ac\ud574\ubd80\ud559\uc801 \uc99d\uac70\ub97c \uc2e4\uc2dc\ud588\ub2e4. \uc911\uad6d\uc758 DMSO \uc808\ubc18\ub7c9\uc5d0 \ud574\ub2f9\ud558\ub294 LG50 \uac12\uc740 (22.4)\uc774\ub2e4. \u00b11.4)g\/kg\uc73c\ub85c, \uc774\ub294 \ud574\uc678 \ubb38\ud5cc\uc5d0 \ubcf4\uace0\ub41c 21.4g\/kg\uacfc \uae30\ubcf8\uc801\uc73c\ub85c \uc77c\uce58\ud55c\ub2e4. \ub530\ub77c\uc11c DMSO\ub294 \ubb34\ub3c5\uc131\uc774\uba70 \ubcd1\ub9ac\ud559\uc801 \ubd80\uac80 \uc18c\uacac\uacfc \uc77c\uce58\ud558\ub294 \uac83\uc73c\ub85c \ud310\ub2e8\ub41c\ub2e4. 1960\ub144\ub300 \ubd81\uacbd\uc5f0\ud569\uc758\uacfc\ub300\ud559\ubcd1\uc6d0 \ub4f1 160\uac1c \uc758\ub8cc\uae30\uad00\uc5d0\uc11c \uc784\uc0c1\uc2dc\ud5d8\uc744 \uc2e4\uc2dc\ud558\uace0 \ubc88\uc2dc(\u672c\u6eaa)\uc5d0 \uc804\ubb38\uc9c4\ub8cc\uc18c\ub97c \uc124\ub9bd\ud574 \ub9ce\uc740 \uc591\uc758 \ub370\uc774\ud130\ub97c \ucd95\uc801\ud588\ub294\ub370, \uc774\ub294 \uc2e0\uacbd\ud53c\ubd80\uc5fc, \uac74\uc120, \uad00\uc808\uc5fc, \ud65c\uc561\ub0ad\uc5fc, \ubaa8\ub0ad\uc5fc\uc5d0 \ud6a8\uacfc\uac00 \uc788\uc74c\uc774 \uc785\uc99d\ub410\ub2e4. , \ub958\ub9c8\ud2f0\uc2a4 \uc9c8\ud658, \uc911\uc774\uc5fc, \ube44\uc5fc, \ubd80\uc18d\uae30\uc5fc, \uce58\ud1b5, \uc218\ud3ec, \uce58\uc9c8, \uc5fc\uc88c, \uc694\ucd94 \uadfc\uc721 \uae34\uc7a5, \ud654\uc0c1, \uc678\uc0c1 \ub4f1. \ud604\uc7ac \uc678\uc6a9\uc81c\ub85c\ub294 \uae30\uc5ec\ub9c1, \uac01\uae30\uc57d, \ud478\ud788\ub4dc\ub85c\ud540 \uc5f0\uace0 \ub4f1 \uc678\uc6a9\uc57d\ud488\uacfc \ub300\ud615\ubcd1\uc6d0\uc758 \uc0dd\uc0b0\uc774 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\ub2e4. \uc911\uad6d\uacfc\ud559\uc6d0 \uc218\uc758\ud559 \uc5f0\uad6c\uc18c\uc5d0\uc11c\ub294 DMSO\uc6a9\ud574\uc131 \"Paz\"\ub97c \uc0ac\uc6a9\ud558\uc5ec \ub9d0\uc758 \uac10\uc5fc\uc131 \ube48\ud608 \ubc0f \uae30\uc0dd\ucda9 \uc9c8\ud658\uc744 \uce58\ub8cc\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubbf8\uad6d\uacfc \uc720\ub7fd\uc5d0\uc11c\ub294 DMSO\uac00 \uc784\uc0c1 \ucc98\ubc29\uc57d\uc5d0 \ubaa8\ub450 \uc0ac\uc6a9\ub418\uba70 \uc288\ud37c\ub9c8\ucf13\uc5d0\uc11c \uacf5\uac1c\uc801\uc73c\ub85c \ud310\ub9e4\ub418\ub294 \ub2e4\uc591\ud55c \ub18d\ub3c4\uc758 \"\uc6a9\ub9e4\"\uac00 \uc788\uc73c\uba70 \uc18c\ube44\uc790\uac00 \uc9c1\uc811 \uad6c\uc785\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc678\uc6a9\uc73c\ub85c \uc0ac\uc6a9\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc544 \uace8\uad00\uc808\uc5fc \uce58\ub8cc\uc5d0 \uc88b\uc740 \ud6a8\uacfc\ub97c \ubc1b\ub294 \uacbd\uc6b0\uac00 \ub9ce\ub2e4.<\/p>\n

DMSO\uc758 \uac04\ub7b5\ud55c \uc5ed\uc0ac<\/p>\n

DMSO\ub294 1866\ub144 \ub7ec\uc2dc\uc544 \uc758\uc0ac Alexander M. Saytzeff\uc5d0 \uc758\ud574 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 1950\ub144\ub300 \uc601\uad6d \uacfc\ud559\uc790\ub4e4\uc740 DMSO\uac00 \uace8\uc218\uc640 \ud608\uc561 \uc138\ud3ec\ub97c \uc800\uc7a5\ud558\ub294 \ubd80\ub3d9\uc561\uc73c\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\uc74c\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \ubaa9\uc7ac \ud384\ud504 \uc0b0\uc5c5\uc5d0\uc11c \ubc1c\uc0dd\ud558\ub294 \uc774 \ub3c5\ud2b9\ud55c \ubd80\uc0b0\ubb3c\uc740 \uc0b0\uc5c5\uc6a9 \uc6a9\uc81c \ubc0f \ud398\uc778\ud2b8 \ud76c\uc11d\uc81c\ub85c\ub3c4 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1950\ub144\ub300 \ud6c4\ubc18, \uc138\uacc4 \ucd5c\ub300\uc758 \uc81c\uc9c0 \uacf5\uc7a5 \uc911 \ud558\ub098\uc778 Crown Zellerbach Corporation\uc740 \ud654\ud559\uc790 Robert Herschler\uc5d0\uac8c DMSO\uc758 \ub2e4\ub978 \uc6a9\ub3c4\ub97c \ucc3e\uc544\ub2ec\ub77c\uace0 \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4. \uc218\ub9ce\uc740 \uc2e4\ud5d8 \ub05d\uc5d0 Herschel\uc740 \ud2b9\uc815 \ud56d\uc0dd\uc81c \ubc0f \ud56d\uacf0\ud321\uc774\uc81c\uc640 \ud63c\ud569\ub41c DMSO\uac00 \uc2dd\ubb3c\uc758 \uc21c\ud658\uacc4\uc5d0 \uce68\ud22c\ud560 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \ud654\ud559\ubb3c\uc9c8\uc5d0\ub3c4 \uc774\ub7ec\ud55c \ub2a5\ub825\uc774 \uc788\uc9c0\ub9cc DMSO\ub294 \uc2dd\ubb3c \uc138\ud3ec \uc678\uce35\uc758 \ubcf4\ud638 \ucf54\ud305\uc744 \ubcc0\uacbd\ud558\uac70\ub098 \uc190\uc0c1\uc2dc\ud0a4\uc9c0 \uc54a\ub294\ub2e4\ub294 \uc810\uc5d0\uc11c \ub2e4\ub978 \ud654\ud559\ubb3c\uc9c8\uacfc \ub2e4\ub985\ub2c8\ub2e4.<\/p>\n

Herschel\uc740 DMSO\uac00 \uc758\ud559\uc801 \uc6a9\ub3c4\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc744 \ub54c \ub2f9\uc2dc \uc624\ub808\uace4 \ub300\ud559\uc758 \uc678\uacfc \ubd80\uad50\uc218\uc600\ub358 \uc624\ub79c \uce5c\uad6c Stanley Jacob \ubc15\uc0ac\uc5d0\uac8c \ub9d0\ud588\uc2b5\ub2c8\ub2e4. Jacob\uc740 \uc774\uc2dd\uc6a9 \uc7a5\uae30\ub97c \ub0c9\ub3d9\ud558\uace0 \ubcf4\uc874\ud558\ub294 \ub0c9\ub3d9\uc0dd\ubb3c\ud559\uc744 \uc804\ubb38\uc73c\ub85c \ud569\ub2c8\ub2e4. \uadf8\uc758 \uc5f0\uad6c\ub85c \uc778\ud574 \uadf8\ub294 DMSO\uc5d0 \ubd80\ub3d9\uc561 \ud2b9\uc131\uc774 \uc788\ub2e4\ub294 \uac83\uc744 \uc54c\uace0 \uc788\uc5c8\uc9c0\ub9cc DMSO\uac00 \uc138\ud3ec\ub9c9\uc5d0\ub3c4 \uce68\ud22c\ud560 \uc218 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc5d0 \ub180\ub790\uace0 Jacob\uc740 DMSO\uac00 \ud2b9\uc815 \ubb3c\uc9c8\uc744 \ud53c\ubd80\ub97c \ud1b5\ud574 \ud608\uc561\uc73c\ub85c \uc6b4\ubc18\ud560 \uc218\ub3c4 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc5d0 \ub354\uc6b1 \ub180\ub790\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc608\ube44 \ub3d9\ubb3c \uc5f0\uad6c\uc5d0\uc11c\ub294 DMSO\uc758 \ub3c5\uc131\uc774 \ub9e4\uc6b0 \ub0ae\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \uc790\uc2e0\uacfc \ub2e4\ub978 \uc0ac\ub78c\ub4e4\uc5d0\uac8c DMSO\ub97c \uc0ac\uc6a9\ud588\uace0, \uadf8 \uacb0\uacfc DMSO\uac00 \uc2e0\uc18d\ud558\uac8c \ud1b5\uc99d\uc744 \uc644\ud654\ud558\uace0 \ub450\ud1b5\uc744 \uba48\ucd94\uba70 \uc2ec\uc9c0\uc5b4 \uadfc\uc721 \uc5fc\uc88c\uc640 \ud654\uc0c1\uc744 \ube60\ub974\uac8c \ud68c\ubcf5\ud558\uace0 \ud68c\ubcf5\ud560 \uc218 \uc788\uc74c\uc774 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc624\ub808\uace4 \ub300\ud559\uad50 \uc5f0\uad6c \ubcf4\uc870\uae08\uc740 \ucd94\uac00\uc801\uc778 \uc778\uac04 \uc5f0\uad6c\ub97c \uc9c0\uc6d0\ud558\uace0 \uc788\uc73c\uba70 Herschler\ub294 \ucd08\uae30 \uacb0\uacfc\uc5d0 \uace0\ubb34\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

Crown Zelerbach\ub294 DMSO\uc5d0 \ub300\ud55c \uc758\uc57d \ud2b9\ud5c8\ub97c \uc624\ub808\uace4 \uc8fc \uc815\ubd80\uc5d0 \uc2e0\uccad\ud588\uc73c\uba70 \uc81c\uc548\ub41c \uc758\ud559\uc801 \uc6a9\ub3c4\ub294 \uacf5\uac1c \uac80\ud1a0\ub97c \uc704\ud574 \uacf5\uac1c\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

1963\ub144 12\uc6d4 10\uc77c, \uc624\ub808\uace4\uc8fc \ud3ec\ud2c0\ub79c\ub4dc \uc9c0\uc5ed \uc2e0\ubb38\uc740 DMSO\uc758 \uae30\ub2a5\uc744 1\uba74 \uae30\uc0ac\uc5d0 \uae30\uc7ac\ud558\uace0 \uc774\ub97c \uae30\uc801\uc758 \uce58\ub8cc\ubc95\uc774\ub77c\uace0 \ubd88\ub800\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc758\ud559\uacc4\uc5d0\uc11c\ub294 \uc774\ub7ec\ud55c \uc0c8\ub85c\uc6b4 \uc5f0\uad6c \uacb0\uacfc\ub97c \ub300\uc911 \ub9e4\uccb4\uac00 \uc544\ub2cc \uc801\uc808\ud55c \uacfc\ud559 \uc800\ub110\uc5d0 \uba3c\uc800 \ubc1c\ud45c\ud560 \uac83\uc744 \uc694\uad6c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

1963\ub144 FDA\ub294 DMSO\ub97c \uc778\uccb4 \uc2e4\ud5d8\uc6a9\uc73c\ub85c \uc2b9\uc778\ud588\uc73c\uba70, \uc77c\ubd80 \ub300\ud615 \uc81c\uc57d\ud68c\uc0ac\ub294 \ucd1d 2\uc5b5 5\ucc9c\ub9cc \ub2ec\ub7ec\ub97c \uc9c0\ucd9c\ud558\uace0 10\ub9cc \uba85 \uc774\uc0c1\uc744 \ub300\uc0c1\uc73c\ub85c \ud14c\uc2a4\ud2b8\ud558\ub294 \ub4f1 \uc804\ub840 \uc5c6\ub294 \uc218\uc758 \uc2e4\ud5d8\uc744 \uc218\ud589\ud588\uc73c\uba70, \uac01 \uc2e4\ud5d8 \uadf8\ub8f9\uc5d0\uc11c DMSO\uac00 \ub9e4\uc6b0 \uc548\uc804\ud558\uace0 \uc548\uc804\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc774 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud6a8\uacfc\uc801\uc778 \ubb3c\uc9c8. \uc778\uac04\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc2e4\ud5d8\uc5d0\ub294 \uc911\ub3c5 \ubb38\uc81c\uac00 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc81c\uc57d\ud68c\uc0ac\uc778 Merck\uc758 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\ub97c \ud22c\uc5ec\ubc1b\uc740 \uc77c\ubd80 \ub3d9\ubb3c\uc758 \ub208 \uc218\uc815\uccb4\uc5d0 \uc57d\uac04\uc758 \ud63c\ud0c1\ud55c \ubcc0\ud654\uac00 \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. 1965\ub144 12\uc6d4 25\uc77c, \uba38\ud06c\uc758 \uc5f0\uad6c\uc5d0 \uae30\ucd08\ud558\uc5ec FDA\ub294 DMSO\uc758 \ubaa8\ub4e0 \uc778\uac04 \uc0ac\uc6a9\uc744 \uae08\uc9c0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc804 \uc138\uacc4\uc801\uc73c\ub85c DMSO\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \uacc4\uc18d\ud574\uc11c \uadf8 \uc548\uc804\uc131\uc744 \uc785\uc99d\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. 1967\ub144\uc5d0 FDA\ub294 \uc81c\ud55c\ub41c \uc778\uac04 \uc5f0\uad6c\ub97c \ub2e4\uc2dc \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc62c\ud574 Vacaville \uc5f0\uad6c(\uc544\ub798 \uc790\uc138\ud788 \uc124\uba85)\uc5d0\uc11c\ub294 DMSO \uc0ac\uc6a9\uc774 \uc778\uac04\uc758 \ub208\uc5d0 \uc804\ud600 \ubb34\ud574\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. \uc774 \ub370\uc774\ud130\uc640 \uae30\ud0c0 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c FDA\ub294 1968\ub144\uc5d0 \uc778\uccb4 \ud14c\uc2a4\ud2b8 \ubc94\uc704\ub97c \ub354\uc6b1 \ud655\ub300\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub3d9\uc548 \uc5ec\ub7ec \uc81c\uc57d\ud68c\uc0ac\uac00 DMSO \uc2dc\ud310\uc744 FDA\uc5d0 \uc2e0\uccad\ud588\uc9c0\ub9cc \ubaa8\ub450 \uac70\uc808\ub2f9\ud588\uc2b5\ub2c8\ub2e4. FDA \uad00\uacc4\uc790\ub294 DMSO \uc0ac\uc6a9\uc744 \uac15\ub825\ud788 \ubc18\ub300\ud569\ub2c8\ub2e4. \uadf8\ub4e4\uc740 DMSO\uc640 \uadf8 \uc9c0\uc9c0\uc790\ub4e4\uc744 \ubc18\ub300\ud558\ub294 \ubaa9\uc18c\ub9ac\ub97c \ub0c8\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 DMSO\uac00 \uacb0\ucf54 \uc2dc\uc7a5\uc5d0 \ucd9c\uc2dc\ub418\uc5b4\uc11c\ub294 \uc548 \ub41c\ub2e4\uace0 \uc8fc\uc7a5\ud588\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc \ub9ce\uc740 \uc81c\uc57d\ud68c\uc0ac\ub4e4\uc774 DMSO \uc5f0\uad6c\ub97c \uc911\ub2e8\ud588\uc2b5\ub2c8\ub2e4. \ubd88\ud589\ud558\uac8c\ub3c4 \uc774\ub4e4 \uc81c\uc57d\ud68c\uc0ac\uac00 \uc5f0\uad6c\ud55c 100,000\uac74 \uc774\uc0c1\uc758 \uc0ac\ub840 \uc911 \uacf5\uac1c\ub41c \uc0ac\ub840\ub294 \ubd88\uacfc \uba87 \ucc9c \uac74\uc5d0 \ubd88\uacfc\ud569\ub2c8\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 3,000\uac1c \uc774\uc0c1\uc758 \ubc1c\ud45c\ub41c \uc5f0\uad6c\uc5d0\uc11c DMSO\ub294 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc758\ud559 \uc5ed\uc0ac\uc0c1 \uac00\uc7a5 \uc548\uc804\ud55c \uc57d\ubb3c \uc911 \ud558\ub098\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

1970\ub144\ub300 \uc911\ubc18, \uc720\ud0c0\uc758 \ud55c \ud68c\uc0ac\ub294 \ub9c8\uce68\ub0b4 \uac04\uc9c8\uc131 \ubc29\uad11\uc5fc \uce58\ub8cc\ub97c \uc704\ud574 DMSO\ub97c \uc2dc\ud310\ud558\uae30 \uc704\ud55c FDA \uc2b9\uc778\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\uc758 \uc0dd\ubb3c\ud559\uc801 \ubc18\uc751<\/p>\n

\ub300\ubd80\ubd84\uc758 \uc57d\uc81c\uc5d0\ub294 \ud55c\ub450 \uac00\uc9c0 \uc0dd\ubb3c\ud559\uc801 \ubc18\uc751\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ubd80\ub294 \uac10\uc5fc\uacfc \uc2f8\uc6b0\uace0, \ub2e4\ub978 \uc77c\ubd80\ub294 \uadfc\uc721\uc744 \uc774\uc644\uc2dc\ud0a4\uace0, \uc2ec\ubc15\uc218\ub97c \ub2a6\ucd94\uace0, \uacfc\ub3c4\ud55c \uccb4\uc561\uc744 \uc81c\uac70\ud558\ub294 \ub4f1\uc758 \uc791\uc5c5\uc744 \ud569\ub2c8\ub2e4. \uc2ec\uac01\ud55c \ubd80\uc791\uc6a9\uc744 \uc77c\uc73c\ud0a4\uc9c0 \uc54a\uc73c\uba74\uc11c DMSO\ub9cc\ud07c \ub9ce\uc740 \uae30\ub2a5\uc744 \uac16\uace0 \uc788\ub294 \ubb3c\uc9c8\uc740 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n

1. \ud53c\ubd80\uc5d0 \uce68\ud22c<\/p>\n

DMSO\uc758 \uac00\uc7a5 \ub3c5\ud2b9\ud55c \uce21\uba74\uc740 \ud53c\ubd80 \ubcf4\ud638\ub9c9\uc744 \uc190\uc0c1\uc2dc\ud0a4\uac70\ub098 \ubcc0\uacbd\uc2dc\ud0a4\uc9c0 \uc54a\uace0 \ud53c\ubd80\uc5d0 \uce68\ud22c\ud558\ub294 \ub2a5\ub825\uc785\ub2c8\ub2e4. \uc54c\ucf54\uc62c, \ud718\ubc1c\uc720, \uc544\uc138\ud1a4(\uc544\uc138\ud1a4), \uc554\ubaa8\ub2c8\uc544(\uc554\ubaa8\ub2c8\uc544)\ub3c4 \ud53c\ubd80\ub97c \uce68\ud22c\ud574 \ud608\ub958\ub85c \ub4e4\uc5b4\uac08 \uc218 \uc788\uc9c0\ub9cc \uc2ec\uac01\ud55c \uc190\uc0c1\uc744 \uc77c\uc73c\ud0ac \uc218 \uc788\ub2e4. \u2026<\/p>\n

DMSO\uc758 \uce68\ud22c\ub294 \uc870\uc9c1\ub9c8\ub2e4 \ub2e4\ub985\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \ubc29\uad11\uc740 \uad00\ud1b5\ud558\uae30 \uc27d\uc9c0\ub9cc \ubf08\ub294 \uad00\ud1b5\ud558\uae30\uac00 \ub354 \uc5b4\ub835\uc2b5\ub2c8\ub2e4. DMSO\uc758 \ub18d\ub3c4\ub3c4 \uce68\ud22c\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. 90% \ub18d\ub3c4(10% \uc99d\ub958\uc218 \ud568\uc720)\uc758 DMSO\ub294 \uc21c\uc218(100%) DMSO\ubcf4\ub2e4 \uce68\ud22c \uc18d\ub3c4\uac00 \ube60\ub985\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c 70-90% DMSO \uc6a9\uc561\uc774 \uc774\uc0c1\uc801\uc785\ub2c8\ub2e4. \ucc98\ubc29 DMSO \uc194\ub8e8\uc158\uc740 50% \ubc0f 100% \ud615\ud0dc\ub85c\ub9cc \uc81c\uacf5\ub429\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc591\ud55c \ubb3c\uc9c8\uc744 \ud53c\ubd80\uc5d0 \uc804\ub2ec\ud558\ub294 DMSO\uc758 \ub2a5\ub825\uc5d0 \ub300\ud574 \ub9ce\uc740 \uc798\ubabb\ub41c \uc815\ubcf4\uac00 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4 \ud398\ub2c8\uc2e4\ub9b0, \uc2a4\ud14c\ub85c\uc774\ub4dc, \ud2b9\ud788 \ud558\uc774\ub4dc\ub85c\ucf54\ub974\ud2f0\uc190\uacfc \uac19\uc740 \uc800\uc9c8\ub7c9 \ubd84\uc790\ub294 \uc6b4\ubc18\uc774 \ub354 \uc27d\uace0 DMSO\uc640 \ud63c\ud569\ub418\uc5b4 \ud53c\ubd80\uc5d0 \ub354 \ud6a8\uc728\uc801\uc73c\ub85c \uce68\ud22c\ud55c\ub2e4\uace0 \ub9d0\ud558\ub294 \uc0ac\ub78c\ub4e4\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \uc778\uc290\ub9b0, \ubc15\ud14c\ub9ac\uc544, \ubc14\uc774\ub7ec\uc2a4 \ub4f1\uc740 \ub108\ubb34 \ucee4\uc11c \uc804\ub2ec\uc774 \ubd88\uac00\ub2a5\ud569\ub2c8\ub2e4. \uc2e4\uc81c\ub85c, \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\uc5d0 \uc758\ud574 \uc804\ub2ec\ub420 \uc218 \uc788\ub294 \ubb3c\uc9c8\uc740 \uc790\uccb4\uc801\uc73c\ub85c \ud53c\ubd80\uc5d0 \uce68\ud22c\ud560 \uc218 \uc788\ub294 \ub2a5\ub825\uc774 \uc788\uc9c0\ub9cc \ubb3c\uc9c8\uc774 \ud53c\ubd80\uc640 \ucda9\ubd84\ud788 \uc624\ub7ab\ub3d9\uc548 \uc9c1\uc811 \uc811\ucd09\ud55c \uacbd\uc6b0\uc5d0\ub9cc \uac00\ub2a5\ud569\ub2c8\ub2e4. DMSO \uc218\uc1a1 \ubb3c\uc9c8\uc758 \ud2b9\uc131\uc740 \uc885\uc885 \uacfc\uc7a5\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

2. \ud1b5\uc99d \uc644\ud654<\/p>\n

\ud1b5\uc99d\uc740 \uae09\uc131 \ub610\ub294 \ub9cc\uc131\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc6b4\ub3d9 \uc5fc\uc88c\uc640 \uac19\uc740 \uae09\uc131 \ud1b5\uc99d\uc740 \uc77c\ubc18\uc801\uc73c\ub85c DMSO\ub97c \uc0ac\uc6a9\ud558\uba74 5~30\ubd84 \uc774\ub0b4\uc5d0 \uc644\ud654\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc2ec\ud55c \uad00\uc808\uc5fc\uacfc \uac19\uc740 \ub9cc\uc131 \ud1b5\uc99d\uc740 1~6\uc8fc \ub610\ub294 \uadf8 \uc774\uc0c1 \uac78\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\ubcf4\ub2e4 \uc6b0\uc218\ud55c \uad6d\uc18c \uc9c4\ud1b5\uc81c\ub294 \uc5c6\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ub9ce\uc740 \uc9c4\ud1b5\uc81c\uc5d0\uc11c \ub098\ud0c0\ub098\ub294 \ub9c8\uc57d\uc131 \ubd80\uc791\uc6a9\ub3c4 \uc5c6\uc2b5\ub2c8\ub2e4. Emory School of Medicine\uc758 \ub3d9\ubb3c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\ub294 \uc0dd\uc950\uc758 \ud1b5\uc99d \uc644\ud654\uc5d0 \ubaa8\ub974\ud540\ub9cc\ud07c \ud6a8\uacfc\uc801\uc774\uc5c8\uc9c0\ub9cc \uc804\uc790\ub294 7\uc2dc\uac04 \ub3d9\uc548 \uc9c0\uc18d\ub418\uc5c8\uace0 \ud6c4\uc790\ub294 2\uc2dc\uac04\ub9cc \uc9c0\uc18d\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ub610\ud55c \ub9e4\uc6b0 \uc548\uc804\ud569\ub2c8\ub2e4. \ub300\ubd80\ubd84\uc758 \ub9c8\uc57d\uc131 \uc9c4\ud1b5\uc81c\ub294 \ud658\uc790\uc758 \ud1b5\uc99d \uac10\uac01\uc744 \ubc29\ud574\ud569\ub2c8\ub2e4. DMSO\ub294 \ud574\ub2f9 \ubd80\uc704\uc758 \ud1b5\uc99d\uc744 \uc190\uc0c1\uc2dc\ud0a4\uc9c0 \uc54a\uace0 \ud1b5\uc99d\ub9cc \uc81c\uac70\ud569\ub2c8\ub2e4. DMSO\ub294 \ub610\ud55c \ubc29\ud5a5 \uac10\uac01 \uc0c1\uc2e4, \ube44\ud2c0\uac70\ub9bc, \ubcc0\ube44, \uad6c\ud1a0, \uba54\uc2a4\uaebc\uc6c0, \uad6c\uac15 \uac74\uc870, \ub450\ud1b5, \ubd88\uba74\uc99d, \uc2ec\uc7a5 \ub450\uadfc\uac70\ub9bc, \ubc1c\uae30 \ubd80\uc804 \ub4f1 \ub2e4\ub978 \uc9c4\ud1b5\uc81c\uc5d0 \ud754\ud788 \ub098\ud0c0\ub098\ub294 \ubd80\uc791\uc6a9\ub3c4 \uc5c6\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc9c4\ud1b5\uc81c\uc640 \ub2ec\ub9ac DMSO\ub294 \uc77c\uc815 \uae30\uac04 \uc0ac\uc6a9 \ud6c4 \uc810\uc810 \ub354 \uc801\uc740 \uc591\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n

3, \ud56d\uc5fc\uc99d\uc81c<\/p>\n

\uc5fc\uc99d\uc740 \uc9c1\uc811\uc801\uc778 \uc190\uc0c1(\uadfc\uc721 \uc5fc\uc88c, \uc0c1\ucc98, \ud654\uc0c1, \uc9c4\ub3d9, \ubc29\uc0ac\uc120 \ub4f1) \ub610\ub294 \uac04\uc811\uc801\uc778 \uc190\uc0c1(\uc608: \uac10\uc5fc)\uc5d0 \ub300\ud55c \uc870\uc9c1\uc758 \ubc18\uc751\uc785\ub2c8\ub2e4. \uc5fc\uc99d\uc5d0\ub294 \ud1b5\uc99d, \ubc1c\uc5f4, \ubc1c\uc801, \ubd80\uae30 \ubc0f \uae30\ub2a5 \uc0c1\uc2e4\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4. \uc774\ub294 \uc190\uc0c1\ub41c \ubd80\uc704\ub97c \ubcf5\uad6c\ud560 \uc218 \uc788\ub3c4\ub85d \uc190\uc0c1\ub41c \ubd80\uc704\ub97c \ub458\ub7ec\uc2f8\ub294 \uc2e0\uccb4\uc758 \ud2b9\ubcc4\ud55c \ubc29\ubc95\uc785\ub2c8\ub2e4. DMSO\ub294 \uc5fc\uc99d\uc758 \uc2ec\uac01\uc131\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ubab8 \uc804\uccb4\uc758 \ud608\uc561 \uc21c\ud658\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4. \uc774\ub294 \ud070 \ud608\uad00\uc744 \ud655\uc7a5\uc2dc\ud0a4\uace0 \ubaa8\uc138\ud608\uad00\uc744 \uc218\ucd95\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \uc774\ub294 \uc601\ud5a5\uc744 \ubc1b\uc740 \ubd80\uc704\uc758 \ubd93\uae30\uc640 \uccb4\uc561 \ub204\ucd9c\uc744 \uc904\uc774\ub294 \ub3d9\uc2dc\uc5d0 \uc601\ud5a5\uc744 \ubc1b\uc740 \ubd80\uc704\uc5d0\uc11c \ub3c5\uc18c\uc640 \ub178\ud3d0\ubb3c\uc744 \uc81c\uac70\ud558\ub294 \uc2e0\uccb4\uc758 \ub2a5\ub825\uc744 \ub192\uc774\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4. DMSO\ub294 \ud68c\ubcf5\ud558\ub294 \ub370 \uba87 \uc8fc\uac00 \uac78\ub9ac\ub294 \ubd80\uc0c1\uc744 \uba70\uce60\ub85c \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

4, \ud56d\uade0<\/p>\n

DMSO\ub294 \ub9e4\uc6b0 \ud6a8\uacfc\uc801\uc778 \ub9cc\ub2a5 \uc18c\ub3c5\uc81c\ub294 \uc544\ub2c8\uc9c0\ub9cc \uc911\uac04 \uc815\ub3c4\uc758 \ud56d\uade0 \ud6a8\uacfc\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. 35% DMSO \uc6a9\uc561\uc740 \uad11\ubc94\uc704\ud55c \ubc15\ud14c\ub9ac\uc544\uc640 \uacf0\ud321\uc774\uc758 \uc131\uc7a5\uc744 \uc5b5\uc81c\ud588\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ud2b9\uc815 \ubc15\ud14c\ub9ac\uc544\uac00 \ud56d\uc0dd\uc81c\uc5d0 \ub354 \ubbfc\uac10\ud574\uc9c8 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ud55c \uc5f0\uad6c\uc5d0\uc11c\ub294 5% DMSO \uc6a9\uc561\uc774 \uc2a4\ud2b8\ub819\ud1a0\ub9c8\uc774\uc2e0(TB \uc57d\ubb3c)\uc5d0 \ub300\ud55c \uacb0\ud575\uade0\uc758 \ubbfc\uac10\uc131\uc744 200\ubc30 \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

5, \uc88b\uc740 \uc18c\ubcc0<\/p>\n

\ud53c\ubd80\uc5d0\uc11c DMSO\ub294 \uc57d\uac04\uc758 \uc774\ub1e8 \ud6a8\uacfc\ub9cc \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc62c\ubc14\ub974\uac8c \uc8fc\uc0ac\ud558\uba74 \uac00\uc7a5 \uac15\ub825\ud55c \uc774\ub1e8\uc81c \uc911 \ud558\ub098\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5b4\ub5a4 \uacbd\uc6b0\uc5d0\ub294 \uc18c\ubcc0 \uc0dd\uc0b0\ub7c9\uc774 10\ubc30 \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \ubb3c\uc5d0 \ub300\ud55c DMSO\uc758 \uac15\ud55c \uce5c\ud654\ub825\uc740 \uacfc\ub3c4\ud55c \uccb4\uc561\uc744 \ud608\ub958\ub85c \uc720\uc785\uc2dc\ud0a4\uace0, \uadf8\uacf3\uc5d0\uc11c \uc2e0\uc7a5\uc744 \ud1b5\ud574 \uc5ec\uacfc\ub429\ub2c8\ub2e4. \uc2ec\uac01\ud55c \ub450\ubd80 \ubc0f \ucc99\uc218 \uc190\uc0c1\uc740 \ub1cc\ubd80\uc885\uacfc \ub1cc\uc138\ud3ec \ubd80\uc885\uc744 \uc720\ubc1c\ud558\uc5ec \ub450\uac1c\ub0b4\uc555\uc774 \uc99d\uac00\ud558\uace0 \uc601\uad6c\uc801\uc778 \uc2e0\uacbd \uc190\uc0c1\uc744 \ucd08\ub798\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud0c8\uc218\uc81c \ubc0f \uc774\ub1e8\uc81c\uc778 DMSO\ub294 \uadf8\ub7ec\ud55c \ud658\uc790\uc5d0\uac8c \uc0dd\uba85\uc758 \uc740\uc778\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

5. \ube44\uc815\uc0c1\uc801\uc778 \ucf5c\ub77c\uac90\uc744 \uc608\ubc29<\/p>\n

\ucf5c\ub77c\uac90\uc740 \uc5f0\ud569\uad70\uc744 \uad6c\uc131\ud558\ub294 \ub2e8\ubc31\uc9c8\uc758 \uc77c\uc885\uc785\ub2c8\ub2e4. \ube44\uc815\uc0c1\uc801\uc778 \ucf5c\ub77c\uac90 \ucd95\uc801\uc740 \ub3d9\ub9e5\uacbd\ud654\uc99d\uacfc \uad00\uc808\uc5fc\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5b4\ub5a4 \uacbd\uc6b0\uc5d0\ub294 DMSO\uac00 \ube44\uc815\uc0c1\uc801\uc778 \ucf5c\ub77c\uac90\uc744 \ubd80\ub4dc\ub7fd\uac8c \ud558\uace0 \uc2ec\uc9c0\uc5b4 \uc81c\uac70\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ud1a0\ub07c \uc2e4\ud5d8\uc5d0\uc11c\ub294 DMSO\uac00 \uace0\ucf5c\ub808\uc2a4\ud14c\ub864 \uc2dd\ub2e8\uc73c\ub85c \uc778\ud55c \ub3d9\ub9e5 \uacbd\ud654\ub97c \uc608\ubc29\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

6. \uba74\uc5ed\uccb4\uacc4 \uac15\ud654<\/p>\n

DMSO\uac00 \uba74\uc5ed\uccb4\uacc4 \ubc0f \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc5d0 \ub300\ud55c \uc5f0\uad6c\ub294 \uc81c\ud55c\uc801\uc785\ub2c8\ub2e4. \ub3d9\ubb3c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\ub294 \uc911\uc99d \uadfc\ubb34\ub825\uc99d\uc5d0 \ub300\ud55c \uc790\uac00\uba74\uc5ed \ud56d\uccb4\ub97c \uac10\uc18c\uc2dc\ud0a4\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

7. \uadfc\uc721\uc744 \uc774\uc644\ud558\uc138\uc694<\/p>\n

DMSO\ub294 \uadfc\uc721\uc758 \ud608\uc561 \uc21c\ud658\uc744 \uac1c\uc120\ud558\uace0 \uadfc\uc721 \uacbd\ub828\uc744 \uc77c\uc73c\ud0a4\ub294 \ub3c5\uc131 \ubb3c\uc9c8\uacfc \ub300\uc0ac \ud3d0\uae30\ubb3c\uc744 \uc81c\uac70\ud569\ub2c8\ub2e4. \ubc24\uc5d0 \uadfc\uc721\uacbd\ub828\uc744 \uc644\ud654\ud558\ub294\ub370 \uc88b\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ub2e4\ub978 \uadfc\uc721 \uc774\uc644\uc81c\ucc98\ub7fc \uc911\ucd94\uc2e0\uacbd\uacc4\ub97c \ud30c\uad34\ud558\uac70\ub098 \ub9c8\ube44\uc2dc\ud0a4\uc9c0 \uc54a\uc73c\uba70 \ub9ce\uc740 \ubd80\uc791\uc6a9\uc744 \ud53c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub2e4\uc591\ud55c \uc99d\uc0c1\uc5d0 \ub300\ud55c DMSO\uc758 \ud6a8\ub2a5<\/p>\n

1. \uc544\ubc00\ub85c\uc774\ub4dc\uc99d<\/p>\n

\uc18c\ub7c9\uc758 \uc544\ubc00\ub85c\uc774\ub4dc\uac00 \ubab8 \uc804\uccb4\uc5d0\uc11c \ubc1c\uacac\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc544\ubc00\ub85c\uc774\ub4dc\uc99d\uc740 \uc7a5\uae30\uc5d0 \uc544\ubc00\ub85c\uc774\ub4dc \uc12c\uc720\uac00 \ucd95\uc801\ub418\ub294 \uac83\uc785\ub2c8\ub2e4. \uc99d\uc0c1\uc740 \ucd95\uc801\ub41c \uc704\uce58\uc640 \uc591\uc5d0 \ub530\ub77c \ub2e4\ub985\ub2c8\ub2e4. \uac04, \uc2e0\uc7a5, \ube44\uc7a5, \uc2ec\uc7a5\uc758 \uae30\ub2a5\uc744 \ubc29\ud574\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \ub2e4\ub9ac, \ubc1c, \uc190, \ud314\uc5d0 \uc2e0\uacbd \uc555\ubc15\uacfc \ud1b5\uc99d\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4(\uc218\uadfc\uad00 \uc99d\ud6c4\uad70\uc758 \uc99d\uc0c1\uacfc \uc720\uc0ac). \ub2e4\ub978 \uac00\ub2a5\ud55c \uc99d\uc0c1\uc73c\ub85c\ub294 \uc7a5 \ucd9c\ud608, \ubd88\uaddc\uce59\ud55c \uc2ec\uc7a5 \ubc15\ub3d9, \ud53c\ubd80 \uc885\uae30 \ubc0f \ubcc0\uc0c9 \ub4f1\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc54c\uce20\ud558\uc774\uba38\ubcd1 \ub610\ub294 \uce58\ub9e4\ub294 \ub1cc \uc138\ud3ec\uc758 \uc544\ubc00\ub85c\uc774\ub4dc\uc99d\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ub1cc\uc544\ubc00\ub85c\uc774\ub4dc\ud608\uad00\ubcd1\uc99d\uc740 \ub178\uc778\uc131 \ub1cc\ud608\uad00\uc9c8\ud658\uc758 \uc77c\uc885\uc774\ub2e4. \uc784\uc0c1\uc801 \ud2b9\uc9d5\uc740 \uce58\ub9e4, \uc815\uc2e0\uc99d\uc0c1, \ubc18\ubcf5\uc801\uc774\uac70\ub098 \ub2e4\ubc1c\uc131 \uc18c\uc5fd\ucd9c\ud608 \ub4f1\uc774\ub2e4.<\/p>\n

\uc778\uac04 \uc2e4\ud5d8\uc5d0 \ub530\ub974\uba74 DMSO\ub85c \uce58\ub8cc\ubc1b\uc740 \ubaa8\ub4e0 \ud658\uc790\uc5d0\uc11c 24\uc2dc\uac04 \uc774\ub0b4\uc5d0 \uc544\ubc00\ub85c\uc774\ub4dc\uac00 \uc18c\ubcc0\uc73c\ub85c \uc644\uc804\ud788 \ubc30\uc124\ub420 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uacbd\uad6c \ub610\ub294 \uc815\ub9e5 DMSO \ud658\uc790\ub294 \uc544\ubc00\ub85c\uc774\ub4dc \uc885\uc591\uc744 \ubd84\ud574\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

2. \uad00\uc808\uc5fc<\/p>\n

DMSO\ub294 \uad00\uc808\uc5fc\uc73c\ub85c \uc778\ud55c \uc218\ubc31 \uac00\uc9c0 \uc720\ud615\uc758 \uc5fc\uc99d\uacfc \ud1b5\uc99d\uc744 \uce58\ub8cc\ud558\ub294 \ub370 \ud6a8\uacfc\uc801\uc778 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uae09\uc131 \ubc0f \ub9cc\uc131 \ud1b5\uc99d\uc5d0 \ud6a8\uacfc\uac00 \uc788\uc9c0\ub9cc \uae09\uc131 \ud1b5\uc99d\uc5d0\ub294 \ub354 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4.<\/p>\n

DMSO\uc758 \ud56d\uc5fc\uc99d \ud2b9\uc131\uc740 \uba87 \uac00\uc9c0 \uc911\uc694\ud55c \ud2b9\uc131 \uc678\uc5d0\ub3c4 \uad00\uc808\uc5fc \uce58\ub8cc \ubc0f \ud1b5\uc99d \uc644\ud654\uc5d0 \ud6a8\uacfc\uc801\uc77c \uc218 \uc788\ub294 \uc774\uc720\uc785\ub2c8\ub2e4. \uadf8\uac83\uc740 \uc790\uc720 \ub77c\ub514\uce7c\uc744 \uccad\uc18c\ud569\ub2c8\ub2e4. \uc790\uc720 \ub77c\ub514\uce7c\uc740 \uc2e0\uccb4 \ub0b4\uc5d0\uc11c \ub610\ub294 \uc2e0\uccb4 \uc678\ubd80 \uc694\uc778\uc5d0 \uc758\ud574 \uc0dd\uc131\ub418\ub294 \uc720\ud574 \ubb3c\uc9c8\uc785\ub2c8\ub2e4. \ud65c\uc131\uc0b0\uc18c \uc81c\uac70\uc81c\ub85c \uc54c\ub824\uc9c4 \uc288\ud37c\uc625\uc0ac\uc774\ub4dc \uce74\ud0c8\ub77c\uc81c \ub514\uc2a4\ubba4\ud0c0\uc81c(SOD), \ube44\ud0c0\ubbfc A, E, C \ub4f1\uacfc \uac19\uc740 \ud2b9\uc815 \ud6a8\uc18c\ub294 \ud65c\uc131\uc0b0\uc18c\ub97c \ubb34\ud574\ud55c \ubb3c\uc9c8\ub85c \uc804\ud658\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uad00\uc808\uc5fc\uacfc \uad00\ub828\ub41c \uac83\uc740 \ud558\uc774\ub4dc\ub85d\uc2e4 \ub77c\ub514\uce7c\uc774\uba70, DMSO\ub294 \uac15\ub825\ud55c \ud558\uc774\ub4dc\ub85d\uc2e4 \ub77c\ub514\uce7c \uc81c\uac70\uc81c\uc785\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ud65c\uc131 \uc0b0\uc18c\uac00 \uad00\uc808 \uc0ac\uc774\uc758 \uc724\ud65c\uc744 \ud30c\uad34\ud558\ub294 \uac83\uc744 \ubc29\uc9c0\ud558\uace0, \ucda9\ubd84\ud55c \uad00\uc808 \uc724\ud65c\uc740 \uae09\uc131 \uad00\uc808\uc5fc\uc758 \ud1b5\uc99d\uacfc \uc5fc\uc99d\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ub610\ud55c \uad00\uc808 \uc774\ub3d9\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ub9cc\uc131 \uad00\uc808\uc5fc\uc744 \uc548\uc815\ud654\uc2dc\ud0a4\uba70, \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc \ud658\uc790\uc758 \uc870\uc9c1 \uc190\uc0c1\uc744 \uc77c\uc73c\ud0a4\ub294 \uc790\uac00\uba74\uc5ed \ud56d\uccb4\uc758 \uc218\ub97c \uc904\uc77c \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uc744 \uc870\uae30\uc5d0 \uce58\ub8cc\ud560\uc218\ub85d \ubc18\uc751\uc774 \uc88b\uc544\uc9c0\uace0, \uc99d\uc0c1\uc774 \uae38\uc5b4\uc9c8\uc218\ub85d DMSO\uc758 \ud6a8\uacfc\uac00 \ub35c \uc911\uc694\ud574\uc9c0\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc801\uc808\ud55c \uc601\uc591 \uc12d\ucde8\uc640 \ud568\uaed8 DMSO\ub97c \uc0ac\uc6a9\ud55c \uc7a5\uae30 \uce58\ub8cc\uac00 \ub354 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \uc9c8\ubcd1\uc758 \uc5f0\ub839, \ub2e8\uacc4 \ubc0f \uc911\uc99d\ub3c4\uc5d0 \uad00\uacc4\uc5c6\uc774 \uace8\uad00\uc808\uc5fc \uce58\ub8cc\uc5d0 \ub9e4\uc6b0 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \ub300\ud1f4\uace8, \ubb34\ub98e, \uc5b4\uae68 \ub4f1 \uad00\uc808\uc774 \ud070 \uacbd\uc6b0\uc5d0\ub294 \uce58\ub8cc \uae30\uac04\uc774 \ub354 \uae38\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf9\ub2e8\uc801\uc778 \uacbd\uc6b0\uc5d0\ub294 DMSO \uc8fc\uc785\uc774 \uc678\uc6a9\ubcf4\ub2e4 \ud6a8\uacfc\uc801\uc774\ub2e4.<\/p>\n

\uad00\uc808\uc5fc\uc5d0 \ub300\ud55c DMSO\uc758 \uc218\ub9ce\uc740 \uc2e4\ud5d8\uc774 \ubbf8\uad6d\uacfc \ud574\uc678\uc5d0\uc11c \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 1960\ub144\ub300 \ucd08 \uc77c\ubcf8\uc758 \ub958\ub9c8\ud2f0\uc2a4\ud559\ud68c, \ubbf8\uad6d\uc758 \uc2e0\ud14d\uc2a4 \uc5f0\uad6c\uc18c, \ub3c5\uc77c\uc758 \uc758\uc0ac \uadf8\ub8f9 \ub4f1\uc774 \ubaa8\ub450 \ube44\uc2b7\ud55c \uc5f0\uad6c\ub97c \uc9c4\ud589\ud55c \uacb0\uacfc DMSO\uac00 \uad00\uc808\uc5fc\uc758 \uc5fc\uc99d\uacfc \ud1b5\uc99d \uce58\ub8cc\uc5d0 \ud6a8\uacfc\uc801\uc774\ub77c\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. Sintax \uc5f0\uad6c\uc2e4\uc758 Arthur \ubc15\uc0ac\ub294 DMSO\uac00 \uad00\uc808 \uc774\ub3d9\uc131\uc744 \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\ub2e4\uace0 \ub9d0\ud569\ub2c8\ub2e4. 1972\ub144\uc5d0\uc11c 1978\ub144 \uc0ac\uc774\uc5d0 DMSO\ub97c \ud14c\uc2a4\ud2b8\ud55c \ud6c4, \ub7ec\uc2dc\uc544 \uacfc\ud559\uc790\ub4e4\uc740 \"DMSO\uac00 \uc5fc\uc99d\uc131 \ubc0f \ud1f4\ud589\uc131 \uad00\uc808 \uc9c8\ud658\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\ub2e4\ub294 \ucda9\ubd84\ud55c \uc99d\uac70\uac00 \uc788\ub2e4\"\uace0 \uacb0\ub860\uc9c0\uc5c8\uc2b5\ub2c8\ub2e4. \ud658\uc790\ub4e4\uc740 \ubd80\uc791\uc6a9\uc774 \uac70\uc758 \uc5c6\uc774 DMSO\ub97c \ud3ec\ud568\ud55c \ub2e4\uc591\ud55c \uce58\ub8cc\ubc95\uc744 \uc870\ud569\ud558\uc5ec \ubc1b\uc744 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4.\u201d<\/p>\n

\ud65c\uc561\ub0ad\uc5fc, \ub2f9\ub1e8\ubcd1, \uce58\ud1b5, \uadc0 \uc9c8\ud658, \uc548\uacfc \uc9c8\ud658, \uc624\uc2ed\uacac, \ud1b5\ud48d, \ub450\ud1b5, \ubd80\ud488\ud5e4\ub974\ud398\uc2a4, \uac04\uc9c8\uc131 \ubc29\uad11\uc5fc, \uc815\uc2e0\uc9c0\uccb4, \ucf67\ubb3c\ud3f4\ub9bd, \uc2e0\uacbd\uc5fc, \ud1b5\uc99d, \ud30c\ud0a8\uc2a8\ubcd1, \uce58\uc8fc\uc9c8\ud658, \uc131\ud615\uc678\uacfc, \uc608\ubc29, \uac74\uc120, \uc18c\uc591\uc99d , \ub808\uc774\ub178\ubcd1 \uc9c8\ud658), \ube44\uacbd\ud654\uc885, \ubd80\ube44\ub3d9\uc5fc, \ub300\uc0c1\ud3ec\uc9c4, \uadfc\uc721 \uc5fc\uc88c, \uc815\ub9e5\ub958.<\/p>\n

DMSO\uc758 \ud2b9\uc218 \uc6a9\ub3c4<\/p>\n

1. \ub0c9\uc0c1<\/p>\n

\ub3d9\ubb3c \uc2e4\ud5d8\uc5d0 \ub530\ub974\uba74 \uc870\uc9c1 \ub3d9\uacb0 \uc804\uc5d0 DMSO\ub97c \uc801\uc6a9\ud558\uba74 \uc870\uc9c1 \uc190\uc0c1\uc744 \ud53c\ud560 \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc2dc\uccb4\ub97c 24\uc2dc\uac04 \ub3d9\uc548 \ub0c9\ub3d9\uc2dc\ud0a8 \ud6c4 DMSO\ub97c \uc801\uc6a9\ud558\uc5ec \uc545\ud654\ub098 \uc808\ub2e8\uc774 \ud544\uc694 \uc5c6\ub294 \uc644\uc804\ud55c \ud68c\ubcf5\uc744 \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc77c\ub9ac\ub178\uc774\uc8fc\uc5d0\uc11c \uadf9\uc801\uc778 \ub3d9\uc0c1 \uc0ac\ub840\uac00 \ubc1c\uc0dd\ud588\uc2b5\ub2c8\ub2e4. 59\uc138 \uc5ec\uc131\uc774 \ud55c\ubc24\uc911\uc5d0 \uc9d1 \ubc16\uc73c\ub85c \ubbf8\ub044\ub7ec\uc838 \ub098\uac14\ub2e4\uac00 6\uc2dc\uac04 \ub9cc\uc5d0 \ubc1c\uacac\ub410\ub2e4. \ubc14\uae65 \uae30\uc628\uc740 \uc601\ud558 26\ub3c4. \uc751\uae09\uc2e4\uc5d0\uc11c\ub294 \ud658\uc790\uac00 \ubc29\ud5a5 \uac10\uac01\uc774 \uc5c6\uace0 \ub300\ub2f5\ud560 \uc218 \uc5c6\uc73c\uba70 \ubd88\uaddc\uce59\ud55c \uc2ec\uc7a5 \ubc15\ub3d9, \uc815\uc0c1 \uc9c1\uc7a5 \uc628\ub3c4\ubcf4\ub2e4 \ub0ae\uace0 \uc190\ubc1c\uc774 \ubcf4\ub77c\uc0c9, \ubb34\ub98e, \uc67c\ubc1c, \uc624\ub978\ucabd \uc5c4\uc9c0\ubc1c \uc190\uac00\ub77d\uc5d0 \uc5bc\uc74c\uc774 \uc788\uace0 \ud658\uc790\uac00 \ubaa8\ub4e0 \uac10\uac01\uc744 \uc783\uc5c8\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \uc704\uc758 \ubd80\ubd84\ub4e4.<\/p>\n

12\uc2dc\uac04 \ud6c4\uc5d0\ub294 \uc804\ud1b5\uc801\uc778 \uce58\ub8cc\ubc95\uc774 \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0b4\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc758\uc0ac\ub294 65% DMSO \uc6a9\uc561\uc744 \ud658\ubd80\uc5d0 \ub3c4\ud3ec\ud588\uace0, 10\ubd84 \ub9cc\uc5d0 \ud608\uc561\uc21c\ud658\uc774 \uc88b\uc544\uc84c\uace0 \ud658\uc790\ub294 \ub2e4\uc74c\ub0a0 \uc758\uc2dd\uc744 \ub418\ucc3e\uc558\ub2e4. \ud55c \ub2ec \ub3d9\uc548 1\uac24\ub7f0 \uc774\uc0c1\uc758 DMSO \uc6a9\uc561\uc774 \uc0ac\uc6a9\ub418\uc5c8\uc73c\uba70 \ud658\uc790\ub294 \uc0ac\uc9c0 \uc190\uc0c1 \uc5c6\uc774 \uc815\uc0c1\uc73c\ub85c \ub3cc\uc544\uc654\uc2b5\ub2c8\ub2e4.<\/p>\n

1\ub144 \ub4a4 \uc5ec\uc131\uc740 \ub118\uc5b4\uc9c4 \ub4a4 DMSO\ub97c \uc0ac\uc6a9\ud55c \ub4a4 20\ub144 \uc804\ubcf4\ub2e4 \uc190 \ud53c\ubd80\uac00 \ubd80\ub4dc\ub7ec\uc6cc\uc84c\uace0 \uba38\ub9ac\uce74\ub77d\ub3c4 \uad75\uc5b4\uc9c0\uace0 \uc9d9\uc5b4\uc84c\uc73c\uba70 \uc190\ud1b1\ub3c4 \ub35c \ubd80\uc11c\uc84c\ub2e4\uace0 \ub9d0\ud588\ub2e4.<\/p>\n

2. \ubc29\uc0ac\uc120 \ud53c\ud574<\/p>\n

\uc77c\ubcf8 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\ub294 \ubc29\uc0ac\uc120 \uce58\ub8cc\ub97c \ubc1b\ub294 \ud658\uc790\uc758 \ud53c\ubd80\ub97c \ubcf4\ud638\ud558\uc5ec \uc870\uc0ac\ub41c \ud53c\ubd80\ub97c \ub354 \ube68\ub9ac \ud68c\ubcf5\uc2dc\ud0ac \uc218 \uc788\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n

3. \ub1cc \ubc0f \ucc99\uc218 \uc190\uc0c1<\/p>\n

Jakob \ubc15\uc0ac\ub294 \ub3d9\ubb3c \uc5f0\uad6c\uc640 \uc778\uac04 \uc0ac\uc6a9\uc5d0 \uadfc\uac70\ud558\uc5ec \uba38\ub9ac \ubd80\uc0c1 \ud6c4 1\uc2dc\uac04 \uc774\ub0b4\uc5d0 DMSO\ub97c \uc0ac\uc6a9\ud558\uba74 \uc0ac\ub9dd\uc774\ub098 \ub9c8\ube44\ub97c \uc608\ubc29\ud560 \uc218 \uc788\ub2e4\uace0 \ub9d0\ud569\ub2c8\ub2e4.<\/p>\n

\ub300\ubd80\ubd84\uc740 \uc0ac\uace0 \ubc1c\uc0dd \ud6c4 1~4\uc2dc\uac04 \uc774\ub0b4\uc5d0 10~40% DMSO \uc6a9\uc561\uc744 \uc815\ub9e5 \uc8fc\uc0ac\ud569\ub2c8\ub2e4. \ub450\uac1c\uace8\uc758 \uc555\ub825\uc744 \uc644\ud654\ud558\ub294 DMSO\uc758 \ub2a5\ub825\uc740 \ud0c0\uc758 \ucd94\uc885\uc744 \ubd88\ud5c8\ud569\ub2c8\ub2e4.<\/p>\n

\uc0c1\ucc98 \ud608\uc561 \uc18d\uc758 \ucca0\uacfc \uad6c\ub9ac\ub294 \ud65c\uc131\uc0b0\uc18c\ub97c \uc720\ubc1c\ud558\ub294\ub370 DMSO\ub294 \ud53c\ubd80\uc5d0 \ube60\ub974\uac8c \uce68\ud22c\ud558\uc5ec \uc774\ub7ec\ud55c \ud65c\uc131\uc0b0\uc18c\uc758 \ud615\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \uc2e0\uacbd\uacfc \uc8fc\ubcc0 \uc870\uc9c1\uc758 \uc190\uc0c1\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1<\/p>\n

DMSO\uc758 \ud56d\uc554 \ud6a8\uacfc<\/p>\n

1974\ub144 4\uc6d4, \uc5d1\uc190 \uc624\uc77c \uc0b0\uc5c5\uc758 \ucd1d\ucc45\uc784\uc790\uc778 \uc870\uc149 \ud50c\ub85c\uc774(56\uc138)\ub294 \uc9c1\uc7a5 \ucd9c\ud608\ub85c \uc778\ud55c \ub300\uc7a5\uc120\uc554\uc885 \uc9c4\ub2e8\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc7a5 \uc120\uc554\uc885\uc740 \ubaa8\ub4e0 \uc5f0\ub839\ub300\uc758 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc601\ud5a5\uc744 \uc8fc\uc9c0\ub9cc, \ub098\uc774\uac00 \ub4e4\uc218\ub85d \uc704\ud5d8\uc774 \ub354 \ub192\uc544\uc9d1\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc2ed\uc774\uc9c0\uc7a5, \ub54c\ub85c\ub294 \ud68c\uc7a5\uc5d0\uc11c \ubc1c\uacac\ub418\uba70 \uc7a5 \ud3d0\uc1c4, \ud1b5\uc99d, \ucd9c\ud608 \ubc0f \uae09\uaca9\ud55c \uccb4\uc911 \uac10\uc18c\ub97c \uc720\ubc1c\ud569\ub2c8\ub2e4. \ud50c\ub85c\uc774\uc528\uc758 \uc554\uc740 \uadf8\uc758 \ub300\uc7a5\uc744 \uce68\ubc94\ud588\uc2b5\ub2c8\ub2e4. \uc0dd\uc874\uae30\uac04\uc740 \uc7a5\ubcbd\uc758 \uc815\ub3c4, \ub9bc\ud504\uc808 \uc804\uc774, \uc804\uc774 \uac70\ub9ac\uc5d0 \ub530\ub77c \uacb0\uc815\ub418\uc5c8\ub2e4. \ubd88\ud589\ud558\uac8c\ub3c4 \ud50c\ub85c\uc774\uc758 \uc554\uc740 \ub9bc\ud504\uc808\ub85c \ud37c\uc838 \uac04\uc73c\ub85c \uc804\uc774\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

13\uc778\uce58 \ub300\uc7a5\uacfc \ubcf5\ubd80 \ub9bc\ud504\uc808\uc744 \uc81c\uac70\ud558\ub294 \uc218\uc220\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. Harley \ubc15\uc0ac\ub294 \uc120\uc554\uc885\uc774 \uba87 \ub2ec \uc548\uc5d0 \uc7ac\ubc1c\ud560 \uac83\uc774 \ud655\uc2e4\ud558\uae30 \ub54c\ubb38\uc5d0 \ud654\ud559 \uc694\ubc95\uc744 \ubc1b\ub3c4\ub85d \uc870\uc5b8\ud588\uace0, \uc758\uc0ac\ub294 \uc790\uc2e0\uc758 \uc544\ub0b4\uac00 \uc120\uc554\uc885\uc744 \uc553\uace0 \uc788\uc5b4 \ud654\ud559 \uc694\ubc95\uc744 \ubc1b\uace0 \uc788\ub2e4\uace0 \ub9d0\ud588\uc2b5\ub2c8\ub2e4. \ud50c\ub85c\uc774 \uc528\ub294 \uc774 \ubb38\uc81c\ub85c \uc5b4\ub824\uc6c0\uc744 \uacaa\uc5c8\uc9c0\ub9cc \uacb0\uad6d \ud654\ud559 \uc694\ubc95\uc744 \uac70\ubd80\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub294 2\ub144 \uc804\uc5d0 \ud734\uc2a4\ud134\uc758 E. J. \ud130\ucee4 \ubc15\uc0ac\uac00 \uc554\uc744 \uce58\ub8cc\ud588\ub2e4\ub294 \ud154\ub808\ube44\uc804 \ubcf4\ub3c4\ub97c \ubd24\uace0 \ud50c\ub85c\uc774 \uc528\uac00 \uadf8 \uc0ac\uc2e4\uc744 \uc54c\uace0 \uc2f6\uc5b4 \ud588\ub2e4\ub294 \uc0ac\uc2e4\uc744 \uae30\uc5b5\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \uc9c1\uc7a5 \uc218\uc220 \ud6c4 \ud1a0\uc694\uc77c\uc5d0 \ud1f4\uc6d0\ud588\uace0, \uc6d4\uc694\uc77c\uc5d0\ub294 \uadf8\uc640 \uadf8\uc758 \uc544\ub0b4\uac00 \ud130\ucee4 \ubc15\uc0ac\ub97c \ubc29\ubb38\ud588\uc2b5\ub2c8\ub2e4. \ub9ce\uc740 \uace0\ubbfc \ub05d\uc5d0 \u201cDr. \ud130\ucee4\ub294 \ub098\uc5d0\uac8c \uc2e4\ud5d8\uc801\uc778 \uce58\ub8cc\ub97c \uc81c\uacf5\ud558\ub294 \ub370 \ub3d9\uc758\ud588\uc2b5\ub2c8\ub2e4.\u201d \ud50c\ub85c\uc774 \uc528\uac00 \ub9d0\ud588\uc2b5\ub2c8\ub2e4.' 6\uc8fc \ub9cc\uc5d0 \ud574\ub9ac \ubc15\uc0ac\uc758 \uc544\ub0b4\uac00 \ud654\ud559 \uc694\ubc95\uc73c\ub85c \uc0ac\ub9dd\ud588\uc2b5\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \uc800\ub294 \uc9c1\uc7a5\uc73c\ub85c \ub3cc\uc544\uac00 \uce58\ub8cc\ub97c \uc704\ud574 \uc774\ud2c0\uc5d0 \ud55c \ubc88\uc529 Dr. Tucker\ub97c \ub9cc\ub0ac\uc2b5\ub2c8\ub2e4. \ub098\ub294 \uba54\uc2a4\uaebc\uc6c0, \uad6c\ud1a0 \ub610\ub294 \ud654\ud559 \uc694\ubc95\uc758 \uc77c\ubc18\uc801\uc778 \ubd80\uc791\uc6a9\uc774 \uc5c6\uc5c8\uc73c\uba70 \uc57d 18\uac1c\uc6d4 \ud6c4 \ub0b4 CEA \ud14c\uc2a4\ud2b8\ub294 \uc815\uc0c1\ubcf4\ub2e4 \ud6e8\uc52c \ub0ae\uc558\uace0 Tucker \ubc15\uc0ac\ub294 \ub098\uc5d0\uac8c \uc554\uc774 \uc5c6\ub2e4\uace0 \uc120\uc5b8\ud588\uc2b5\ub2c8\ub2e4. \uadf8 \uc774\ud6c4\ub85c \ub9e4\ub2ec \uac80\uc0ac\ub97c \ubc1b\uc558\uace0, \uc9c0\uae08\uc740 3~4\uac1c\uc6d4\uc5d0 \ud55c \ubc88\uc529 \uac80\uc0ac\ub97c \ubc1b\uace0 \uc788\ub294\ub370, CEA \ubc88\ud638\ub294 \ud56d\uc0c1 \ud3c9\uc18c\ubcf4\ub2e4 \ub0ae\uc2b5\ub2c8\ub2e4.\u201d \ud50c\ub85c\uc774 \uc528\uc758 A.A.G. 18\uc5d0\uc11c 0\uc73c\ub85c \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

1983\ub144 5\uc6d4 16\uc77c, 65\uc138\uc758 \ud50c\ub85c\uc774 \uc528\ub294 \uc740\ud1f4\ud558\uace0 \ud14d\uc0ac\uc2a4\uc758 \uc791\uc740 \ub9c8\uc744\uc5d0 \uc791\uc740 \uac74\uac15\uc2dd\ud488 \ub9e4\uc7a5\uc744 \uc5f4\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub294 \ud130\ucee4 \ubc15\uc0ac\uc758 \ud68c\ubcf5\uacfc \uc0dd\uc874\uc5d0 \ub300\ud574 \uacf5\ub85c\ub97c \uc778\uc815\ud569\ub2c8\ub2e4.<\/p>\n

\ud50c\ub85c\uc774 \uce58\ub8cc\ubc95\uc740 1966\ub144 \ud130\ucee4 \ubc15\uc0ac\uc5d0 \uc758\ud574 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

2<\/p>\n

Dmso-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \ub3d9\ubb3c \uc2e4\ud5d8<\/p>\n

\ud734\uc2a4\ud134\uc5d0\uc11c 52\ub144 \ub3d9\uc548 \uc9c4\ub8cc\ub97c \ud574 \uc628 78\uc138 \uc131\ud615\uc678\uacfc \uc758\uc0ac\uc778 Eli Jordon Tucker, Jr., M.D.\ub294 \ub2e4\uc591\ud55c \uad00\uc808 \ud658\uc790\ub4e4\uc5d0\uac8c 1,000\ud68c \uc774\uc0c1\uc758 \uad00\uc808 \uc218\uc220\uc744 \uc2dc\ud589\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

1962\ub144\uc5d0 \ud130\ucee4\ub294 \uc18c\uc704 \uc554 \ud56d\uccb4\uac00 \uc788\uc744 \uc218 \uc788\ub2e4\ub294 \uc0dd\uac01\uc744 \ud588\uc2b5\ub2c8\ub2e4. \uacfc\ud559\uc790\ub4e4\uc740 \uc778\ud130\ud398\ub860\uc744 \uc5f0\uad6c\ud558\uba74\uc11c \uac19\uc740 \uac83\uc744 \ucc3e\uace0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \ubf08 \uc774\uc2dd\uc6a9 \ubf08 \uc811\ucc29\uc81c\ub97c \uc5f0\uad6c\ud558\ub294 \uac83 \uc678\uc5d0\ub3c4 Tucker \ubc15\uc0ac\ub294 \uc554\uc5d0 \uac78\ub9b0 \uc18c\uc758 \ud608\uc561\uc5d0\uc11c \uc554 \ud56d\uccb4\ub97c \ucc3e\ub294 \ub610 \ub2e4\ub978 \uc5f0\uad6c\ub97c \uc218\ud589\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uadf8\ub294 \uc554\uc138\ud3ec\uc758 \ubcc0\ud654\ub97c \uad00\ucc30\ud558\uae30 \uc704\ud574 \uc554\uc138\ud3ec\uc5d0 \uc0c9\uc744 \uce60\ud558\ub294 \uc5fc\ub8cc\uac00 \ud544\uc694\ud588\uc2b5\ub2c8\ub2e4. \u2026 \ud5e4\ub9c8\ud1a1\uc2e4\ub860\uc740 \uc554\uc138\ud3ec\uac00 \ud55c \uac00\uc9c0 \uc0c9\uc744 \ubd99\uc774\uace0 \uc815\uc0c1 \uc138\ud3ec\uac00 \ub2e4\ub978 \uc0c9, \uc989 \ub2e4\uc0c9\uc131 \uc5fc\ub8cc\ub97c \ubd99\uc774\uac8c \ud560 \uc218 \uc788\ub294 \uc644\ubcbd\ud55c \uc5fc\ub8cc\uc784\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4. \u2026 \ud5e4\ub9c8\ud1a1\uc2e4\ub9b0\uc740 \uc774\uc9c8\uacfc \uc694\ub85c \uac10\uc5fc\uc744 \uce58\ub8cc\ud558\ub294\ub370\ub3c4 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n

\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0\uc744 \uc870\uc9c1 \uc5fc\ub8cc\ub85c \uc0ac\uc6a9\ud560 \ub54c\uc758 \ub2e8\uc810\uc740 \uc218\uc9c0\uc774\ubbc0\ub85c \uc54c\ucf54\uc62c\uc774\ub098 \uc5d0\ud14c\ub974\uc640 \uac19\uc740 \uc77c\ubc18\uc801\uc778 \uc2e4\ud5d8\uc2e4 \uc6a9\ub9e4\uc5d0 \uc6a9\ud574\ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n

1963\ub144\uc5d0 DMSO\ub97c \uc6a9\ub9e4\ub85c \uc0ac\uc6a9\ud558\uc600\uace0 \ud130\ucee4\ub294 \ud5e4\ub9c8\ud1a1\uc2e4\ub9b0\uc744 \uc6a9\ud574\uc2dc\ud0a4\ub294 \uac83\uc774 \ub354 \uc774\uc0c1 \ubb38\uc81c\uac00 \ub418\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ud5e4\ub9c8\ud1a1\uc2e4\ub9b0\uc758 \ud2b9\uc131\uc744 \ubcc0\ud654\uc2dc\ud0a4\uc9c0 \uc54a\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc774\ub97c \uc885\uc591\uc73c\ub85c \uc6b4\ubc18\ud558\uc5ec \uc554\uc138\ud3ec\ub97c \ud2b9\ubcc4\ud55c \uc0c9\uc73c\ub85c \uc5fc\uc0c9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud130\ucee4 \ubc15\uc0ac\uc758 \uce5c\uad6c\uac00 \uc18c\uc720\ud55c \uac1c\ub294 \uac70\ub300 \uc138\ud3ec \ub9bc\ud504\uc885\uc744 \uc553\uace0 \uc788\uc73c\uba70 \uc885\uc591\uc73c\ub85c \ub36e\uc5ec \uc788\uc5b4 \ubaa9\uc774 \ub9c9\ud790 \uac83\uc785\ub2c8\ub2e4. DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561\uc744 \uc8fc\uc0ac\ud55c \uc9c0 2\uc8fc \ud6c4\uc5d0 \uc885\uc591\uc774 \uc644\uc804\ud788 \uc0ac\ub77c\uc84c\uc2b5\ub2c8\ub2e4. \uac1c\ub294 \ub098\uc911\uc5d0 \uc2dd\uc911\ub3c5\uc73c\ub85c \uc0ac\ub9dd\ud588\uc73c\uba70 \ubd80\uac80 \uacb0\uacfc \uc885\uc591 \uc794\uc7ac\ubb3c\uc5d0\uc11c \ud65c\uc131 \uc554\uc138\ud3ec\uac00 \ubc1c\uacac\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc18c\uc138\ud3ec \ub9bc\ud504\uc885\uc744 \uc553\uace0 \uc788\ub294 \ub610 \ub2e4\ub978 \uac1c\uc5d0\uac8c DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0\uc744 \uc8fc\uc0ac\ud588\uc9c0\ub9cc \ud6a8\uacfc\uac00 \uadf9\uc801\uc774\uc9c0 \uc54a\uc544 \uce58\ub8cc\ub97c \uc911\ub2e8\ud55c \uc9c0 \ub450 \ub2ec \ub9cc\uc5d0 \uc0ac\ub9dd\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uc57c\uc0dd\ub9c8\uc758 \uc624\ub978\ucabd \uc55e\ub2e4\ub9ac\uc5d0 \uace8\uc554\uc774 \ubc1c\uc0dd\ud588\uc2b5\ub2c8\ub2e4. DMSO-\uc0ac\ud310\uc561 25cc\uc640 \uc77c\ubc18 \ud3ec\ub3c4\ub2f9 \uc2dd\uc5fc\uc218 500cc\ub97c \ud63c\ud569\ud558\uc5ec 1\ub144\uac04 \uc9c0\uc18d\uc801\uc73c\ub85c \ud22c\uc5ec\ud55c \uacb0\uacfc \uc885\uc591\uc740 \uc0ac\ub77c\uc84c\ub2e4.<\/p>\n

3<\/p>\n

\ud56d\uc554\uc561\uc740 \uc704\ud5d8\uc5d0 \ucc98\ud55c \ud658\uc790\uc5d0\uac8c \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<\/p>\n

Bev \ubc15\uc0ac\ub294 Tucker \ubc15\uc0ac\uc5d0\uac8c \uc8fd\uc5b4\uac00\ub294 \uc218\uc220 \ubd88\uac00\ub2a5\ud55c \uc12c\uc720\uc721\uc885 \ud658\uc790\uc5d0\uac8c DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561\uc744 \uc0ac\uc6a9\ud574 \ubcf4\ub3c4\ub85d \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4. \ud658\uc790\ub294 \ub9d0\uae30 \ud63c\uc218\uc0c1\ud0dc\uc5d0 \ube60\uc84c\uace0, \uadf8\ub140\uc758 \ub0a8\ud3b8\uc740 \ud130\ucee4 \ubc15\uc0ac\uc758 \ub3d9\ubb3c \uc2e4\ud5d8 \uc18c\uc2dd\uc744 \ub4e3\uace0 \ud130\ucee4 \ubc15\uc0ac\uc5d0\uac8c \uacfc\uac10\ud788 \ub6f0\uc5b4\ub4e4\ub3c4\ub85d \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\uce68\ub300 \uc606\uc5d0 \uc549\uc544 \ud130\ucee4 \ubc15\uc0ac\ub294 \ub9e4\uc6b0 \ucc9c\ucc9c\ud788 \uadf8\ub9ac\uace0 \uc870\uc2ec\uc2a4\ub7fd\uac8c IV\ub97c \ud22c\uc5ec\ud588\uace0 \uccab \ubc88\uc9f8 \uc8fc\uc0ac\uc5d0\ub294 6\uc2dc\uac04\uc774 \uac78\ub838\uc2b5\ub2c8\ub2e4. \uba87 \uc8fc\uac04\uc758 \uce58\ub8cc \ud6c4, \uc885\uc591\uc774 \uc218\uc220\uc774 \uac00\ub2a5\ud560 \uc815\ub3c4\ub85c \uc904\uc5b4\ub4e4\uace0 \uc904\uc5b4\ub4e4\uae30 \uc2dc\uc791\ud558\uc5ec \uc218\uc220\uc774 \uc2dc\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud658\uc790\ub294 \uc548\uc804\ud588\uace0 2\ub144 \ud6c4 \uc774\uc0ac\ud558\uba74\uc11c \uc5f0\ub77d\uc774 \ub04a\uacbc\uc2b5\ub2c8\ub2e4.<\/p>\n

Tucker \ubc15\uc0ac\ub294 \uac1c\uc778\uc801\uc73c\ub85c \uad11\ubc94\uc704\ud55c \uc5f0\uad6c\ub97c \uc218\ud589\ud558\uc5ec \ub2e4\uc591\ud55c \uc554\uc5d0 \ub300\ud55c \uc194\ub8e8\uc158\uc758 \ud6a8\uacfc\ub97c \ubb38\uc11c\ud654\ud588\uc2b5\ub2c8\ub2e4. \u2026 \uc545\uc131\uc885\uc591 37\uc608\uc758 \uce58\ub8cc \uacb0\uacfc\ub97c \ubd84\uc11d\ud55c \uacb0\uacfc, DMSO-\uc0ac\ud310\uacfc \ud604\ud589 \ud56d\uc554\ubc95\uc744 \ubcd1\uc6a9\ud558\uba74 \ud658\uc790\uc758 70.5%\ub97c \ud638\uc804\uc2dc\ud0ac \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc5ec\uae30\uc5d0\ub294 \uc218\uc220, \ubc29\uc0ac\uc120, \ud654\ud559 \uc694\ubc95\uc774 \ud3ec\ud568\ub429\ub2c8\ub2e4.<\/p>\n

\uc77c\ubc18 \ud56d\uc554\uce58\ub8cc \ub2e8\ub3c5\uc694\ubc95\uc758 \ud6a8\uacfc\ub294 5.4%\uc600\ub2e4. DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561 \ub2e8\ub3c5\uc73c\ub85c\ub294 \uc218\uc728\uc774 38.1%\uc600\ub2e4. \u2026<\/p>\n

\uac00\uc7a5 \ub208\uc5d0 \ub744\ub294 \uac83\uc740 \uc885\uc591\uc774 \uc644\uc804\ud788 \uc0ac\ub77c\uc9c4 \uac70\ub300\uc138\ud3ec\ub9bc\ud504\uc885 2\uac74\uacfc \uc885\uc591\uc774 \uc644\uc804\ud788 \uc0ac\ub77c\uc9c0\uace0 \uc0c8\ub85c\uc6b4 \ubf08\uac00 \uc790\ub77c\ub09c \uc545\uc131\uac70\ub300\uc138\ud3ec\uace8\uc554 2\uac74\uc774\uc5c8\ub2e4.<\/p>\n

4<\/p>\n

\uc554 \uce58\ub8cc\uc6a9 Dmso-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561<\/p>\n

1968\ub144\uc5d0 \ud130\ucee4 \ubc15\uc0ac\ub294 \uc790\uc2e0\uc758 \uc554 \uc5f0\uad6c\uc640 \uce58\ub8cc\uc5d0 \ub300\ud55c \uacf5\uac1c \ubcf4\uace0\ub97c \uc911\ub2e8\ud588\uc9c0\ub9cc, \uc790\uc2e0\uc744 \ucc3e\uc544\uc628 \uc18c\uc218\uc758 \ud658\uc790 \uce58\ub8cc\ub97c \uc644\uc804\ud788 \uc911\ub2e8\ud558\uc9c0\ub294 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \uadf8\ub294 \uac70\ub300 \uc138\ud3ec \ub9bc\ud504\uc885\uc5d0 \uac78\ub9b0 \ub450 \uba85\uc758 \ud658\uc790\ub97c \uce58\ub8cc\ud588\ub294\ub370, \uadf8 \uc911 \ud55c \uba85\uc740 8\ub144 \ud6c4\uc5d0 \uc2ec\uc7a5\ubcd1\uc73c\ub85c \uc0ac\ub9dd\ud588\uace0, \ub2e4\ub978 \ud55c \uba85\uc740 \uc624\ub298\ub0a0(14\ub144 \ud6c4)\uc5d0\ub3c4 \uc5ec\uc804\ud788 \uc0b4\uc544 \uc788\uc2b5\ub2c8\ub2e4. \ub2f9\uc2dc 38\uc138\uc600\ub358 \uc70c\uc2a8 \ubd80\uc778\uc740 1972\ub144 1\uc6d4 \ud3d0, \ud68c\uc7a5 \ub3d9\ub9e5, \uc8fc\uc694 \ub3d9\ub9e5 \uc8fc\ubcc0 \ub9bc\ud504\uc808\uc5d0 \ud070 \uc885\uc591\uc774 \uc788\ub2e4\ub294 \uc120\uc554\uc885 \uc9c4\ub2e8\uc744 \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \ud658\uc790\uc758 \uc18c\uc7a5\uc554\uc740 \uc7a5\uae30\uac04 \uc601\uc591\ud761\uc218\uc7a5\uc560\ub97c \uc77c\uc73c\ucf1c \uc7a5\uae30\uac04\uc758 \uc1e0\uc57d, \uc1e0\uc57d, \ucc3d\ubc31\ud55c \uc810\ub9c9, \uac80\uace0 \uac74\uc870\ud55c \ube44\ub4ec \ub4f1\uc744 \uc77c\uc73c\ud0a8\ub2e4. \ubcf5\ubd80 \ubcf5\uc218, \ubd80\uae30, \uc2ec\ud55c \ube48\ud608, \uace8\uc218\ub85c \uc804\uc774\ub41c \uc554\uc138\ud3ec, \ub9bc\ud504\uc808 \ud30c\uad34. \ud658\uc790\ub294 \uc5b8\uc81c\ub4e0\uc9c0 \uc8fd\uc74c\uc5d0 \uc9c1\uba74\ud569\ub2c8\ub2e4.<\/p>\n

\uc70c\uc2a8 \ubd80\uc778\uc740 \ud55c \ub2ec \ub3d9\uc548 \ucd5c\uace0 \uc6a9\ub7c9\uc758 \ud654\ud559\uc694\ubc95\uc744 \ubc1b\uc558\uace0, \uc774\uc5b4\uc11c \ud55c \ub2ec \ub3d9\uc548 \ud654\ud559\uc694\ubc95\uacfc \ubc29\uc0ac\uc120 \uce58\ub8cc\ub97c \ubc1b\uc558\uc9c0\ub9cc \uc885\uc591\uc740 \uacc4\uc18d\ud574\uc11c \ud37c\uc84c\uc2b5\ub2c8\ub2e4. \uc2ec\uac01\ud55c \ubd80\uc791\uc6a9\uc73c\ub85c \uc778\ud574 \ud654\ud559\uc694\ubc95\uc774 \uc911\ub2e8\ub418\uc5c8\ub294\ub370, \uadf8 \uc911 \ud558\ub098\ub294 \ubc31\ud608\uad6c \uc218\uac00 \ud55c\ub3c4\uc778 5,000 \uc774\ud558\ub85c \ub5a8\uc5b4\uc838 \uc0ac\uc2e4\uc0c1 \uba74\uc5ed\uc774 \ub418\ub294 \uac83\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

1973\ub144 1\uc6d4\ubd80\ud130 1974\ub144 1\uc6d4\uae4c\uc9c0 Tucker \ubc15\uc0ac\ub294 \uc774\ud2c0\uc5d0 \ud55c \ubc88\uc529 DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561\uc744 \ud658\uc790\uc5d0\uac8c \uc815\ub9e5 \uc8fc\uc0ac\ud558\uae30 \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. \uc2dc\uac04\uc774 \uc9c0\ub098\uba74\uc11c \uc885\uc591\uc758 \ubaa8\ub4e0 \uc9d5\ud6c4\ub294 \uc644\uc804\ud788 \uc0ac\ub77c\uc84c\uace0, \ud658\uc790\ub294 \ud604\uc7ac(14\ub144 \ud6c4) \uc544\ubb34\ub7f0 \ubd80\uc791\uc6a9 \uc5c6\uc774 \uc0b4\uc544\uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

1970\ub144 1\uc6d4 14\uc77c, \ud074\ub77c\uc774\ub4dc(Clyde)\ub77c\ub294 3\uc138 \uc18c\ub144\uc774 \uadf8\uc758 \uc5b4\uba38\ub2c8\uc5d0 \uc758\ud574 \ud130\ucee4 \ubc15\uc0ac\uc758 \uc9c4\ub8cc\uc2e4\ub85c \ub370\ub824\uc654\uc2b5\ub2c8\ub2e4. \uadf8 \uc544\uc774\ub294 \uc694\ubd95\uc99d\uc744 \uc553\uace0 \uc788\uc5c8\uace0 \ud14d\uc0ac\uc2a4\uc8fc \ud734\uc2a4\ud134\uc5d0 \uc788\ub294 \uc544\ub3d9\ubcd1\uc6d0\uc5d0\uc11c \uce58\ub8cc\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \ubd88\ud589\ud558\uac8c\ub3c4 \uadf8\ub294 \uc804\uc774\uc131 \ub0b4\ud53c\uc885(\ub808\ud130\ub7ec-\uc2dc\uc6e8\ubcd1)\uc774 \ubc1c\uc0dd\ud558\uc5ec \uc564\ub354\uc2a8 \uc554\uc13c\ud130\uc5d0\uc11c \uce58\ub8cc\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc5ec\ub7ec \uc554\uc774 \ub450\ud53c\uc640 \uc2e0\uccb4\ub85c \ud37c\uc84c\uace0, \uc591\ucabd \uadc0 \ub0b4\ubd80\uc758 \uc885\uc591\uc73c\ub85c \uc778\ud574 \ubd80\ube44\ub3d9\uc5fc\uc774 \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \ub208, \uadc0, \ucf54, \ubaa9 \uc758\uc0ac\ub294 \uc774 \ubcd1\uc774 \ubd88\uce58\ubcd1\uc774\uace0 6~7\uc138 \uc774\uc0c1\uc740 \uc0b4 \uc218 \uc5c6\ub2e4\ub294 \uacb0\ub860\uc744 \ub0b4\ub838\ub2e4. \uc544\uc774\uc758 \ubcd1 \ub54c\ubb38\uc5d0 \uc544\ubc84\uc9c0\ub294 \uac00\ucd9c\uc744 \ud588\uace0 \ubaa8\uc790\ub294 \uac00\ub09c\uc5d0 \uc2dc\ub2ec\ub838\ub2e4. \uc544\uc774\uc758 \uc5c4\ub9c8\ub294 \ud130\ucee4\uc758 \ub3c5\ud2b9\ud55c \uce58\ub8cc\ubc95\uc744 \ub4e3\uace0 \uadf8\ub97c \ub9cc\ub098\ub7ec \uc654\ub2e4. \ud130\ucee4 \ubc15\uc0ac\ub294 \uadf8\ub97c \ubb34\ub8cc\ub85c \uce58\ub8cc\ud558\uae30\ub85c \ub3d9\uc758\ud588\uc9c0\ub9cc \uc774\ub294 \uc2e4\ud5d8\uc801\uc778 \uce58\ub8cc\ubc95\uc774\uba70 \ubc18\ub4dc\uc2dc \ud6a8\uacfc\uc801\uc778 \uac83\uc740 \uc544\ub2c8\ub77c\uace0 \ub9d0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud130\ucee4 \ubc15\uc0ac\ub294 DMSO-\ud5e4\ub9c8\ud1a1\uc2e4\ub9b0 \uc6a9\uc561 \ud55c \ubcd1\uc744 \uc8fc\uace0 \uc544\uc774\uac00 \uacf5\ubcf5\uc5d0 \uc0bc\ud0ac \uc218 \uc788\ub3c4\ub85d \ub9e4\uc77c \uc544\uce68 \uc6a9\uc561 5\ubc29\uc6b8\uacfc \uc99d\ub958\uc218\ub97c \uc12d\ucde8\ud558\ub77c\uace0 \uc5b4\uba38\ub2c8\uc5d0\uac8c \ub9d0\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \ud3c9\uc18c\ub300\ub85c \uc544\uc774\ub97c \ucc98\uc74c \ub450 \ubcd1\uc6d0\uc5d0 \ub370\ub824\uac00 \uc758\uc0ac\uc5d0\uac8c \uac00\uc11c \uc57d\uc744 \ubc1b\uace0 \uc544\uc774\uac00 \uc5b4\ub5a4 \uc57d\uc744 \uc0bc\ucf30\ub294\uc9c0 \ub9d0\ud558\ub77c\uace0 \ud558\ub354\uad70\uc694.<\/p>\n

\ub2e4\uc74c \ub0a0, \uc544\uc774\uc758 \uc5b4\uba38\ub2c8\uac00 \ud130\ucee4 \ubc15\uc0ac\uc758 \uc9c4\ub8cc\uc18c\ub97c \ucc3e\uc544\uc640 \uc6b8\uba74\uc11c \ubd88\ud3c9\ud588\uc2b5\ub2c8\ub2e4. \uc5b4\ub9b0\uc774 \ubcd1\uc6d0\uc758 \uc758\uc0ac\ub294 \ud654\uac00 \ub098\uc11c \ud130\ucee4 \ubc15\uc0ac\uc758 \uc57d\uc744 \uc0ac\uc6a9\ud558\uba74 \uc5ec\uae30\ub85c \uc624\uc9c0 \ub9d0\ub77c\uace0 \ub9d0\ud588\uc2b5\ub2c8\ub2e4. \u2026<\/p>\n

\uc774\uc81c 17\uc138\uac00 \ub41c \uadf8 \uc544\uc774\ub294 \uc5ec\uc804\ud788 \ud130\ucee4 \ubc15\uc0ac\uc758 \ud56d\uc554\uc81c\ub97c \ub9e4\uc77c \ubcf5\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

5<\/p>\n

Jacob\uc740 DMSO\uc5d0 \ub300\ud574 \uc124\uba85\ud569\ub2c8\ub2e4.<\/p>\n

Jacob \ubc15\uc0ac\ub294 1962\ub144\uc5d0 DMSO(\ub514\uba54\ud2f8\uc124\ud3ed\uc0ac\uc774\ub4dc)\uc758 \ud6a8\ub2a5\uc744 \ubc1c\ud45c\ud588\uc73c\uba70, 30\ub144 \uc774\uc0c1 DMSO\ub97c \uc5f0\uad6c\ud574 \uc654\uc2b5\ub2c8\ub2e4(\uc774 \ucc45\uc740 1993\ub144\uc5d0 \ucd9c\ud310\ub418\uc5c8\uc2b5\ub2c8\ub2e4). Jacob \ubc15\uc0ac\ub294 \uc758\uacfc\ub300\ud559 \ud559\uc7a5\uc774 \uc190\ubaa9 \uad00\uc808\uc5fc \uce58\ub8cc\ub97c \uc704\ud574 DMSO\ub97c \uc694\uccad\ud588\uc744 \ub54c \uc5fc\uc99d\uc5d0 \ub300\ud55c DMSO\uc758 \ud6a8\uacfc\ub97c \uc5f0\uad6c\ud558\uace0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uacb0\uacfc\ub294 \uc720\ub9dd\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

Jacobs \ubc15\uc0ac\ub294 \ub9c8\ube44\uc131 \uad00\uc808\uc5fc\uc744 \uc553\uace0 \uc788\ub294 9\uc138 \uc18c\ub140\uc758 \uc0ac\ub840\ub97c \ub4e4\ub824\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \ubaa9 \uad00\uc808\uc5fc\uc774 \ub108\ubb34 \uc2ec\ud574\uc11c \ud131\uc744 \uc5b4\uae68\ub85c \ub3cc\ub9b4 \uc218 \uc5c6\uc5c8\uace0, \uc624\ub978\ucabd \uc5c9\ub369\uc774\uac00 \ub108\ubb34 \uc544\ud30c\uc11c \uac78\uc744 \uc218\ub3c4 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. . DMSO\ub97c \ud53c\ubd80\uc5d0 \ud55c \uc2dc\uac04 \ub3d9\uc548 \ub3c4\ud3ec\ud55c \ud6c4 \uc18c\ub140\ub294 \ucc9c\ucc9c\ud788 \ud131\uc744 \uc5b4\uae68\ucabd\uc73c\ub85c \ub3cc\ub9b4 \uc218 \uc788\uc5c8\uc9c0\ub9cc \uac77\ub3c4\ub85d \uc694\uccad\ud558\uc790 \ub108\ubb34 \uace0\ud1b5\uc2a4\ub7ec\uc6cc \uac70\ubd80\ud588\uc2b5\ub2c8\ub2e4. \ub9c8\uce68\ub0b4 \uadf8\ub140\ub294 \uadf8\uac83\uc744 \uc2dc\ub3c4\ud574 \ubcf4\uaca0\ub2e4\uace0 \ud588\uc744 \ub54c \ub208\ubb3c\uc744 \ud130\ub728\ub838\uc2b5\ub2c8\ub2e4. Jacob \ubc15\uc0ac\uac00 \uadf8\ub140\uc5d0\uac8c \uc65c \uc6b8\uace0 \uc788\ub294\uc9c0 \ubb3c\uc5c8\uc744 \ub54c, \uadf8\ub140\ub294 \ud750\ub290\uaef4 \uc6b8\uc5c8\uc2b5\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \uace0\ud1b5\uc774 \uc0ac\ub77c\uc84c\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ud53c\ubd80\uacbd\ud654\uc99d\uc5d0\ub3c4 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \uad6d\uc81c\uacbd\ud53c\uc99d\uc7ac\ub2e8(International Scleroderma Foundation)\uc758 \uad6d\uac00 \uc790\ubb38\uc704\uc6d0 \uc911 \ud55c \uba85\uc778 \uc81c\uc774\ucf65 \ubc15\uc0ac\ub294 DMSO\ub294 \ube44\ub85d \uc0ac\uc6a9\ub7c9\uc774 \uc801\uc9c0\ub9cc \uacbd\ud53c\uc99d\uacfc \ub808\uc774\ub178 \ud604\uc0c1\uc5d0 \ub300\ud55c \ub300\uccb4 \uce58\ub8cc\ubc95\uc774\uba70 \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uc5d0\ub3c4 \ud6a8\uacfc\uc801\uc774\ub77c\uace0 \ub9d0\ud588\ub2e4. \uacbd\ud53c\uc99d \uc7ac\ub2e8 \uc5f0\ub840\ud68c\uc758\uc5d0\uc11c \uadf8\ub294 DMSO \uc774\uc678\uc758 \uce58\ub8cc\ubc95\uc73c\ub85c \ud6a8\uacfc\uc801\uc73c\ub85c \uce58\ub8cc\ubc1b\uc740 \uacbd\ud53c\uc99d \ud658\uc790\ub97c \ub2e8 \ud55c \uba85\ub3c4 \ucc3e\uc744 \uc218 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\ub294 \ud2b9\ud788 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\uc5d0\uac8c \uac15\ub825\ud55c \uc790\uc720 \ub77c\ub514\uce7c \uc815\ud654\uc81c\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4. Jacob \ubc15\uc0ac\ub294 DMSO\uac00 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc5d0 \ub300\ud55c \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc\ubc95\uc774 \ub420 \uc218 \uc788\ub2e4\uace0 \ub9d0\ud569\ub2c8\ub2e4. \uadf8\ub294 \ud6a8\uacfc\uc801\uc778 \uce58\ub9e4 \uce58\ub8cc\uc5d0\ub294 \uc138 \uac00\uc9c0 \uae30\ub2a5\uc774 \uc788\uc5b4\uc57c \ud55c\ub2e4\uace0 \uc9c0\uc801\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\ud608\uc561\ub1cc\uad00\ubb38\uc744 \ub118\uc5b4 \ub1cc\uc138\ud3ec\ub85c \ub4e4\uc5b4\uac00\uae30 \uc27d\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub458\uc9f8, \uac15\ub825\ud55c \ud65c\uc131\uc0b0\uc18c \uc81c\uac70\uc81c<\/p>\n

\uc77c\ubc18\uc801\uc73c\ub85c \uce58\ub9e4 \ud658\uc790\uc758 \ub1cc \uc138\ud3ec\uc5d0 \ucd95\uc801\ub418\ub294 \ube44\uc815\uc0c1\uc801\uc778 \uc810\uc561\uc778 \uc544\ubc00\ub85c\uc774\ub4dc\ub97c \uc6a9\ud574\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n

\uc77c\ubd80 \uc608\ube44 \uc5f0\uad6c\uc5d0\uc11c\ub294 DMSO\uac00 \ud6a8\uacfc\uc801\uc778 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud658\uc790\uc5d0\uac8c DMSO \ub4f1\uc758 \ubb3c\uc9c8\uc744 \uc815\ub9e5 \uc8fc\uc0ac\ud55c \uacb0\uacfc 70%\uac00 3\uac1c\uc6d4 \uc774\ub0b4\uc5d0 \ub2e8\uae30 \uae30\uc5b5\ub825\uc774 25% \ud5a5\uc0c1\ub410\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc774 \uc790\uc5f0\uc801\uc73c\ub85c \ud638\uc804\ub418\ub294 \uc77c\uc740 \uacb0\ucf54 \uc77c\uc5b4\ub098\uc9c0 \uc54a\uc558\uae30 \ub54c\ubb38\uc5d0 \uc774\ub294 \ub180\ub77c\uc6b4 \uc77c\uc785\ub2c8\ub2e4. \uce58\ub9e4\ub294 \ud56d\uc0c1 \uc9c4\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\uc758 \uc548\uc804\uc131<\/p>\n

DMSO\uc5d0\ub294 \ub450 \uac00\uc9c0 \uc77c\ubc18\uc801\uc778 \ubd80\uc791\uc6a9\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ud558\ub098\ub294 \ub9c8\ub298\uc774\ub098 \uad74 \ub0c4\uc0c8\uc774\uace0, \ub2e4\ub978 \ud558\ub098\ub294 \ub3c4\ud3ec\ud55c \ud53c\ubd80\uc5d0 \uc57d\uac04\uc758 \ubc1c\uc801, \uc790\uadf9 \ubc0f \uae30\ud0c0 \ubc18\uc751\uc774 \uc788\uc73c\uba70 \uc5ec\ub7ec \ubc88 \ub3c4\ud3ec\ud55c \ud6c4 \ud53c\ubd80 \ubc18\uc751\uc774 \uc810\ucc28 \uac10\uc18c\ud569\ub2c8\ub2e4.<\/p>\n

\ubc18\ubcf5\ub41c \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 DMSO\uc758 \uc678\ubd80 \uc801\uc6a9\uc740 \uc2ec\uac01\ud55c \ubd80\uc791\uc6a9\uc744 \uc77c\uc73c\ud0a4\uc9c0 \uc54a\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc2e4\uc81c\ub85c DMSO\uac00 \ub3c5\uc131\uc774 \uc788\ub2e4\ub294 \uc5f0\uad6c\ub098 \uc2e4\ud5d8\uc740 \ub2e8 \ud55c \uac74\ub3c4 \uc5c6\uc2b5\ub2c8\ub2e4. 1980\ub144 7\uc6d4 31\uc77c, Jakob \ubc15\uc0ac\ub294 \ubbf8\uad6d \uc0c1\uc6d0 \uc758\ub8cc \uc704\uc6d0\ud68c\uc5d0\uc11c \ub2e4\uc74c\uacfc \uac19\uc740 \uc131\uba85\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n

\u201c\ub9c8\uc57d\uc758 \uac00\uc7a5 \ud070 \ubb38\uc81c\ub294 \ub3c5\uc131\uc785\ub2c8\ub2e4. \ubb34\ub3c5\uc131 \ubb3c\uc9c8\uc774\ub77c\ub294 \uac83\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. DMSO\uc5d0\ub294 \ubd80\uc791\uc6a9\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc8fc\uc694 \ubd80\uc791\uc6a9\uc740 \uc77c\ubd80 \ud658\uc790\uc5d0\uac8c \uc54c\ub808\ub974\uae30\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ub098\ub294 \ub2e4\ub978 \ubb3c\uc9c8\uc5d0 \ub300\ud55c \uc2e4\ud5d8 \ub370\uc774\ud130\ubcf4\ub2e4 \ub3d9\ubb3c\uc5d0 \ub300\ud55c DMSO\uc758 \ub3c5\uc131\uc5d0 \ub300\ud55c \ub354 \ub9ce\uc740 \uc815\ubcf4\uac00 \uc788\ub2e4\uace0 \ubbff\uc2b5\ub2c8\ub2e4. DMSO\ubcf4\ub2e4 \ub354 \uc548\uc804\ud55c \uac83\uc744 \ubcf8 \uc801\uc774 \uc5c6\uc2b5\ub2c8\ub2e4. \ub0b4 \uc0dd\uac01\uc73c\ub85c\ub294 DMSO\ub9cc\ud07c \uc778\uccb4 \ub3c5\uc131\uc5d0 \ub300\ud55c \uc2e4\ud5d8 \ub370\uc774\ud130\uac00 \ub9ce\uc740 \ubb3c\uc9c8\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc5d0\ub9cc 100,000\uac74\uc774 \ub118\ub294 \uc758\ub8cc \uae30\ub85d\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc804 \uc138\uacc4\uc801\uc73c\ub85c DMSO\ub97c \ucc98\ubc29\uc73c\ub85c \uc0ac\uc6a9\ud558\uace0 \uc788\uc74c\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ub098\ub294 \uc798 \ubb38\uc11c\ud654\ub41c \uc911\ub3c5 \uc0ac\ub840\ub97c \uc54c\uc9c0 \ubabb\ud569\ub2c8\ub2e4. \u201d<\/p>\n

DMSO\uc758 \uc0ac\uc6a9<\/p>\n

DMSO\ub294 \uc548\uc804\ud558\uace0 \uc0ac\uc6a9\ud558\uae30 \uc27d\uc2b5\ub2c8\ub2e4. DMSO\uc758 \ubd80\uc791\uc6a9\uc73c\ub85c\ub294 \uac00\ub054 \uba54\uc2a4\uaebc\uc6c0, \ud53c\ubd80 \uc790\uadf9, \ud53c\ubd80\uc640 \ud638\ud761\uc5d0\uc11c \ub9c8\ub298 \uac19\uc740 \ub0c4\uc0c8\uac00 \ub098\uc9c0\ub9cc \uc57d 8\uc2dc\uac04 \ud6c4\uc5d0 \uc0ac\ub77c\uc9d1\ub2c8\ub2e4. \uc12d\ucde8\uc5d0\ub294 \uc815\ub9e5 \uc8fc\uc0ac, \ud53c\ud558 \uc8fc\uc0ac, \uacbd\uad6c \ubcf5\uc6a9, \uad6d\uc18c \ubcf5\uc6a9 \ub4f1 4\uac00\uc9c0 \uc720\ud615\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uacbd\uad6c \ubc0f \uc815\ub9e5 \uc8fc\uc0ac\uac00 \uac00\uc7a5 \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4.<\/p>\n

\uad00\uc808\uc5fc\uacfc \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\uc5d0\uac8c \uc801\ud569\ud569\ub2c8\ub2e4. \uc704\uc7a5\uad00 \uc885\uc591\uc740 \uc815\ub9e5 \ud22c\uc5ec\uc5d0 \uc801\ud569\ud569\ub2c8\ub2e4.<\/p>\n

\ucc98\uc74c\uc5d0\ub294 25% DMSO \uc6a9\uc561\uc744 \uc900\ube44\ud558\uace0(\uc989, 75% \uc99d\ub958\uc218\ub97c \ucca8\uac00) \uc18c\ub7c9\uc744 \ud314\uc5d0 \ubc14\ub974\uace0 15~20\ubd84 \uc815\ub3c4 \uae30\ub2e4\ub9b0 \ud6c4 \ud53c\ubd80 \ubc18\uc751\uc774 \uacbd\ubbf8\ud558\uba74 50%, 75\ub85c \ubcc0\uacbd \uac00\ub2a5 % \ub610\ub294 \uc2ec\uc9c0\uc5b4 90%. \ubd80\uc704\ubcc4\ub85c \ud14c\uc2a4\ud2b8\ud574\ubcf4\uace0, \uc774\uc0c1\uc774 \uc788\uc744 \uacbd\uc6b0\uc5d0\ub294 \ub3c4\ub9d0 \ubd80\uc704\ub85c \uc53b\uc5b4\ub0b8 \ud6c4 \uc77c\ubc18 \uc2a4\ud0a8\ucf00\uc5b4 \ud06c\ub9bc\uc744 \ubc1c\ub77c\uc8fc\uc138\uc694.<\/p>\n

1\ub2e8\uacc4 \uc678\ubd80 \uc2e0\uccad<\/p>\n

\uc601\ud5a5\uc744\ubc1b\ub294 \ubd80\uc704 \ubc0f \uc8fc\ubcc0 \ubd80\uc704\uc5d0 \uc801\uc6a9\ud558\uc2ed\uc2dc\uc624. \uc190\uac00\ub77d, \ud654\uc7a5\uc19c, \uc2a4\ud380\uc9c0(\uba74\ubd09)\ub97c \uac00\ubccd\uac8c \uc0ac\uc6a9\ud558\uc138\uc694. (\uc138\uac8c \ubb38\uc9c0\ub974\uba74 \ud53c\ubd80 \uc790\uadf9\ubc18\uc751\uc774 \uc99d\uac00\ud558\uace0 \ud761\uc218\uc2dc\uac04\uc774 \uae38\uc5b4\uc9d1\ub2c8\ub2e4.) \ub808\uc774\uc628, \uc544\ud06c\ub9b4 \ub610\ub294 \uae30\ud0c0 \ud569\uc131 \uc18c\uc7ac\ub85c \ub9cc\ub4e0 \uc9c1\ubb3c\uc740 DMSO\uc5d0\uc11c \uc27d\uac8c \ubd84\ud574 \ubc0f \uc6a9\ud574\ub429\ub2c8\ub2e4.<\/p>\n

DMSO\ub97c \ud53c\ubd80\uc5d0 \ubc14\ub974\uba74 15\ubd84 \uc774\ub0b4\uc5d0 \ud761\uc218\ub429\ub2c8\ub2e4. \ubd80\ud488\uc744 \ubc14\ub974\uba74 \ud53c\ubd80 \uad6c\uba4d\uc774 \uc57d 30\ubd84 \ub3d9\uc548 \"\uc5f4\ub9b0\" \uc0c1\ud0dc\ub85c \uc720\uc9c0\ub429\ub2c8\ub2e4. \uc548\uc804 \uace0\ub824\uc0ac\ud56d\uc5d0 \ub530\ub77c DMSO \ubd80\ubd84\uc744 \ubc14\ub974\ub294 \uac83\uc740 \ud53c\ud558\ub294 \ub370 \uac00\uc7a5 \uc88b\uc740 3\uc2dc\uac04\uc785\ub2c8\ub2e4. \uc0b4\ucda9\uc81c, \ud398\uc778\ud2b8, \ud45c\ubc31\uc81c, \uba38\ub9ac\uc5fc\uc0c9\uc81c, \ud0c8\ucde8\uc81c, \ud654\uc7a5\ud488, \uc2ec\uc9c0\uc5b4 \uc2e0\ubb38\uacfc \uc9c1\uc811 \u200b\u200b\uc811\ucd09\ud569\ub2c8\ub2e4. \uc704\uc758 \ubb3c\uc9c8\uc5d0 \ub2ff\uc740 \uacbd\uc6b0 \ubd88\ud589\ud558\uac8c\ub3c4 \ubb3c\uacfc \ube44\ub204\ub85c \uc53b\uc73c\uc2ed\uc2dc\uc624.<\/p>\n

\ub3c4\ud3ec \uc804 \uc138\uc548\uc744 \uad8c\uc7a5\ud558\uba70, \uc774\ub294 \ubd88\ud544\uc694\ud558\uba70, \uc816\uc740 \ud53c\ubd80\ub294 DMSO\uc758 \uc21c\ub3c4\ub97c \uc800\ud558\uc2dc\ud0a4\ubbc0\ub85c DMSO \ub3c4\ud3ec \uc804\ud6c4 30\ubd84 \ub3d9\uc548\uc740 \ubaa9\uc695\uc774\ub098 \uc218\uc601\uc744 \ud53c\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4.<\/p>\n

DMSO\uc758 \ud654\ud559\uc801 \ud2b9\uc131 \uc911 \ud558\ub098\ub294 \uc704\ud5d8\ud55c \uc790\uc720 \ub77c\ub514\uce7c\uc744 \ud30c\uad34\ud558\uace0 \ub35c \uc720\ud574\ud55c \uc790\uc720 \ub77c\ub514\uce7c\ub85c \uc804\ud658\ud55c\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \"\ubd80\uc0b0\ubb3c\"\uc744 \uc911\ud654\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub418\ub3c4\ub85d \ud56d\uc0b0\ud654 \ud2b9\uc131\uc774 \uc788\ub294 \ube44\ud0c0\ubbfc\uacfc \ubbf8\ub124\ub784\uc744 \uc12d\ucde8\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. DMSO\ub97c \uc0ac\uc6a9\ud560 \ub54c\ub294 \ube44\ud0c0\ubbfc A, C, E, B1, B6, \uc2dc\uc2a4\ud14c\uc778, \uc544\uc5f0, \uc140\ub808\ub284\uc774 \ud568\uc720\ub41c \uc885\ud569 \ube44\ud0c0\ubbfc\uc81c\ub97c \uc12d\ucde8\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\uc0ac\uc6a9\ub7c9: \ub9e4\ubc88 15~15cc.<\/p>\n

\ud69f\uc218 : \ubc1c\ubaa9 \uc5fc\uc88c, \ub208 \ubc11 \ub2e4\ud06c\uc11c\ud074, \ub3d9\uc0c1, \ud654\uc0c1 \ub4f1 \uae09\uc131 \uc99d\uc0c1\uc774 \ube60\ub974\uac8c \uc2dc\uc791\ub418\uc9c0\ub9cc \uc7ac\ubc1c\ud558\uc9c0 \uc54a\uc74c. \ub9cc\uc131 \uc9c8\ud658\uc774\ub780 \uad00\uc808\uc5fc, \ud1b5\ud48d, \ub9d0\ucd08 \uc21c\ud658\uacc4 \ub4f1\uc774 \uac00\ub77c\uc549\uc9c0 \uc54a\uace0 \uc7a5\uae30\uac04 \uc7ac\ubc1c\ud558\ub294 \uac83\uc744 \ub9d0\ud568 \uc9c8\ubcd1.<\/p>\n

\uae09\uc131 \uc99d\uc0c1\uc740 6~8\uc2dc\uac04 \ub3d9\uc548 2\uc2dc\uac04 \uac04\uaca9\uc73c\ub85c \uc801\uc6a9\ud558\uace0, \uc774\ud6c4 5\uc77c \ub3d9\uc548 4~6\uc2dc\uac04 \uac04\uaca9\uc73c\ub85c \uc801\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>\n

\ub9cc\uc131 \uc99d\uc0c1\uc740 \ub354 \uae34 \uce58\ub8cc \uae30\uac04\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \ub300\ubd80\ubd84\uc758 \uacbd\uc6b0 \uccab \uc8fc \uc774\ub0b4\uc5d0 \uc5b4\ub290 \uc815\ub3c4 \uac1c\uc120\uc744 \ub290\ub084 \uc218 \uc788\uc9c0\ub9cc, \uc77c\ubd80 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc0c1\ub2f9\ud55c \ubcc0\ud654\ub97c \ubcf4\ub824\uba74 6~8\uc8fc\uac00 \uac78\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ucd5c\ub300\uc758 \uacb0\uacfc\ub97c \uc5bb\uc73c\ub824\uba74 \uce58\ub8cc\uc5d0 6\uac1c\uc6d4\uc5d0\uc11c 1\ub144\uc774 \uac78\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\ub9cc\uc131 \uc99d\uc0c1\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \uc99d\uc0c1\uc774 \ud574\uacb0\ub420 \ub54c\uae4c\uc9c0 \ub9e4\uc77c \uc81c\uacf5\ub429\ub2c8\ub2e4. \uc774\ud6c4 DMSO\ub294 '\uc794\ub958 \ud6a8\uacfc'\uac00 \uc788\uae30 \ub54c\ubb38\uc5d0 \uc77c\uc8fc\uc77c\uc5d0 1~2\ud68c \ub3c4\ud3ec\ud558\uba74 \ub41c\ub2e4. \uadf8\ub7ec\ub098 \uc0ac\ub78c\ub9c8\ub2e4 \uac1c\uc778\ucc28\uac00 \uc788\uc73c\ubbc0\ub85c \uc0ac\uc6a9\uc790\uc758 \ud544\uc694\uc5d0 \ub530\ub77c \uc870\uc815\ud574\uc57c \ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c \uc57d\uc740 1\uac1c\uc6d4\uac04 \ud22c\uc5ec\ud558\uace0 1\uac1c\uc6d4\uac04 \uc911\ub2e8\ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc0ac\ub78c\ub4e4\uc740 5\uc77c \ub3d9\uc548 \uc57d\uc744 \ud22c\uc5ec\ud558\uace0 2\uc77c \ub3d9\uc548 \uc911\ub2e8\ud55c \ub2e4\uc74c 6\uac1c\uc6d4\ub9c8\ub2e4 2~4\uc8fc \ub3d9\uc548 \uc911\ub2e8\ud560 \uac83\uc744 \uc81c\uc548\ud569\ub2c8\ub2e4.<\/p>\n

2. \uad6c\uac15\ubcf5<\/p>\n

\ucd08\uae30\uc5d0\ub294 \ub9cc\uc131\uc9c8\ud658(\uc9c0\uc801\uc7a5\uc560, \uad00\uc808\uc5fc, \ud53c\ubd80\uacbd\ud654\uc99d \ub4f1)\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud574 \uc7a0\uc790\ub9ac\uc5d0 \ub4e4\uae30 \uc804\uc5d0 DMSO 1~2\ud2f0\uc2a4\ud47c\uacfc \uc8fc\uc2a4\ub97c \uc12d\ucde8\ud558\ub294 \ubd84\ub4e4\uc774 \ub9ce\uc2b5\ub2c8\ub2e4. DMSO\ub294 \ud53c\ubd80\ubd80\ud130 \uc804\uc2e0\uc73c\ub85c \uce68\ud22c\ud560 \uc218 \uc788\uc73c\uba70, \uacbd\uad6c \ud22c\uc5ec\ud558\uba74 \uc704\uc0b0\uc744 \uac10\uc18c\uc2dc\ud0a4\uace0 \uc2dd\ud488 \uc601\uc591\uc18c\uc758 \ud761\uc218\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ubbc0\ub85c \ub354 \uc774\uc0c1 \uacbd\uad6c \ud22c\uc5ec\ub97c \uad8c\uc7a5\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc5ec\uc804\ud788 \uc18c\uc218\uc758 \uc0ac\ub78c\ub4e4\uc774 \uc0ac\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

3. \uc815\ub9e5 \uc8fc\uc0ac<\/p>\n

\uc774\ub294 \uac04\ub7b5\ud558\uac8c\ub9cc \uc124\uba85\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc8fc\ub85c \uc2ec\uac01\ud55c \ub450\uac1c\ub1cc \uc190\uc0c1\uacfc \ucc99\uc218 \uc190\uc0c1\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c 10-20% DMSO \uc6a9\uc561\uc785\ub2c8\ub2e4. \uc21c\ub3c4 50% \uc774\uc0c1\uc758 \uc6a9\uc561\uc740 \uc8fc\uc0ac \ubd80\uc704\uc758 \uc801\ud608\uad6c\ub97c \ubd84\ud574\ud569\ub2c8\ub2e4. \uc815\ub9e5 DMSO\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \ub450\uac1c\ub0b4 \uc218\uc885 \ubc0f \ub450\uac1c\ub0b4\uc555 \uc870\uc808\uc744 \uc704\ud55c \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc\ubc95\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4.<\/p>","protected":false},"excerpt":{"rendered":"

DMSO is a natural chemical originally found in wood. Over the past 60 years, more than 40,000 articles have been published on this type of DMSO, but the public is not aware of the application of DMSO in medicine and health. Medicine and health refuse to advertise, so unlike ordinary consumer goods, people can be informed about them through advertising. Even in the United States, even complementary foods placed on the open shelves of supermarkets cannot be advertised to spread relevant knowledge. DMSO, approved by the US FDA in 1974, is still only used by a small number of experts and practitioners of alternative medicine and natural medicine in the health and medical fields. DMSO has solution and permeability to many drugs, and it also has anti-inflammatory and analgesic effects. DMSO can promote blood circulation and wound healing, and has diuretic and antistatic effects. It can increase drug absorption and\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[26],"attr":[],"class_list":["post-474","post","type-post","status-publish","format-standard","hentry","category-problems","tag-dmso"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=474"}],"version-history":[{"count":5,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/474\/revisions"}],"predecessor-version":[{"id":1241,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/474\/revisions\/1241"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=474"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}