{"id":378,"date":"2023-12-18T16:19:41","date_gmt":"2023-12-18T08:19:41","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=378"},"modified":"2024-02-02T17:01:11","modified_gmt":"2024-02-02T09:01:11","slug":"dimethyl-sulfoxide-dmso-solvent","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/dimethyl-sulfoxide-dmso-solvent\/","title":{"rendered":"\ub514\uba54\ud2f8\uc124\ud3ed\uc0ac\uc774\ub4dc DMSO \uc6a9\ub9e4"},"content":{"rendered":"<p>DMSO(\ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc)\ub294 \ubb3c \ubc0f \ub2e4\uc591\ud55c \uc720\uae30 \uc6a9\ub9e4\uc640 \uc11e\uc774\ub294 \ub110\ub9ac \uc0ac\uc6a9\ub418\ub294 \uc6a9\ub9e4\uc785\ub2c8\ub2e4. \uc774\ub294 \uba54\ud2f8\uc124\ud3ed\uc0ac\uc774\ub4dc, \uc124\ud53c\ub2d0 \ub514\uba54\ud0c4 \ubc0f \uc218\uc2ed \uac1c\uc758 \uc0c1\ud488\uba85\uc744 \ud3ec\ud568\ud558\uc5ec \uc5ec\ub7ec \uc774\ub984\uc73c\ub85c \ubd88\ub9bd\ub2c8\ub2e4.<\/p>\n<p>DMSO\ub294 \ubaa9\uc7ac \ud384\ud504\ub85c \uc885\uc774\ub97c \ub9cc\ub4dc\ub294 \ub370 \uc0ac\uc6a9\ub418\ub294 \uacf5\uc608 \uc885\uc774 \uacf5\uc815\uc758 \ubd80\uc0b0\ubb3c\ub85c 19\uc138\uae30 \ud6c4\ubc18\uc5d0 \ucc98\uc74c \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ube44\uc2b7\ud55c \uc2dc\uae30\uc5d0 \ub7ec\uc2dc\uc544\uc758 \ud654\ud559\uc790 AlexanderZaytsev\ub294 \uacf5\uc608 \uc885\uc774 \uacf5\uc815\uc758 \ub610 \ub2e4\ub978 \ubd80\uc0b0\ubb3c\uc778 \ud669\ud654\ub514\uba54\ud2f8\uc744 \uc0b0\ud654\uc2dc\ucf1c \uc774\ub97c \ud569\uc131\ud588\uc2b5\ub2c8\ub2e4. Zaytsev\uc758 \ud569\uc131\uc740 \uc624\ub298\ub0a0\uc5d0\ub3c4 \uc5ec\uc804\ud788 \uc0ac\uc6a9\ub418\uace0 \uc788\ub294 \uc81c\uc870 \uacf5\uc815\uc758 \uae30\ucd08\uac00 \ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>DMSO\ub294 \ub2e4\uc591\ud55c \uac00\uc2a4, \ud569\uc131 \uc12c\uc720, \ud398\uc778\ud2b8, \ud0c4\ud654\uc218\uc18c, \uc5fc\ubd84 \ubc0f \ucc9c\uc5f0 \uc81c\ud488\uc744 \uc704\ud55c \uc2e4\ud5d8\uc2e4 \ubc0f \uc0b0\uc5c5\uc6a9 \uc6a9\ub9e4\uc785\ub2c8\ub2e4. \ube44\uc591\uc131\uc790\uc131\uc774\uace0 \uc0c1\ub300\uc801\uc73c\ub85c \ubd88\ud65c\uc131\uc774\uba70 \ub3c5\uc131\uc774 \uc5c6\uace0 \uace0\uc628\uc5d0\uc11c \uc548\uc815\ud558\uae30 \ub54c\ubb38\uc5d0 \ud654\ud559 \ubc18\uc751\uc5d0 \ud754\ud788 \uc0ac\uc6a9\ub418\ub294 \uc6a9\ub9e4\uc785\ub2c8\ub2e4. \uc911\uc218\uc18c\ud654\ub41c \ud615\ud0dc\ub294 \ud575\uc790\uae30\uacf5\uba85 \ubd84\uad11\ud559\uc5d0 \uc774\uc0c1\uc801\uc778 \uc6a9\ub9e4\uc785\ub2c8\ub2e4.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.yearnintl.com\/wp-content\/uploads\/2023\/12\/2024020209004053.jpg\" alt=\"dmso molecular formula\" width=\"379\" height=\"300\" \/><\/p>\n<p>1960\ub144\ub300\uc5d0 \uacfc\ud559\uc790\ub4e4\uc740 DMSO\uac00 \uc870\uc9c1\uc5d0 \uac70\uc758 \uc601\ud5a5\uc744 \uc8fc\uc9c0 \uc54a\uace0 \uc778\uac04\uc758 \ud53c\ubd80\uc5d0 \uce68\ud22c\ud588\ub2e4\ub294 \uac83\uc744 \uad00\ucc30\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \uc6a9\ub9e4\ub294 \uacbd\uad6c \uc81c\uc81c\ub098 \uc8fc\uc0ac\uc81c \ub300\uc2e0 \uc57d\ubb3c\uc744 \uc2e0\uccb4\uc5d0 \uc8fc\uc785\ud558\ub294 \ubc29\ubc95\uc73c\ub85c \ud14c\uc2a4\ud2b8\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8 \uc774\ud6c4\ub85c DMSO\ub294 \uc77c\ubd80 \uacbd\ud53c \uc57d\ubb3c \uc804\ub2ec \uc2dc\uc2a4\ud15c(\uc989, \ud328\uce58)\uc5d0 \uc0ac\uc6a9\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 1978\ub144\uc5d0 \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc740 \ub9cc\uc131 \uac04\uc9c8\uc131 \ubc29\uad11\uc5fc(\ubc29\uad11\ud1b5\uc99d\uc99d\ud6c4\uad70)\uc758 \uc99d\uc0c1\uc744 \uc644\ud654\ud558\ub294 \ub370 \uc0ac\uc6a9\uc744 \uc2b9\uc778\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 FDA\uac00 DMSO\ub97c \uc2e4\uc81c \uc57d\ubb3c\ub85c \uc2b9\uc778\ud55c \uc720\uc77c\ud55c \uc57d\ubb3c\uc785\ub2c8\ub2e4.<\/p>\n<p>1960\ub144\ub300\uc5d0 \uc608\uc0c1\ud560 \uc218 \uc788\ub4ef\uc774 DMSO\ub294 \uc5fc\uc99d\uc744 \uc644\ud654\ud558\uae30 \uc704\ud55c \ub300\uc548\uc774\uc790 \ucf54\uce74\uc778\uacfc \uac19\uc740 \ubd88\ubc95 \uc57d\ubb3c\uc744 \uccb4\ub0b4\uc5d0 \ub3c4\uc785\ud558\ub294 \uc6a9\ub9e4\ub85c \uc2dc\ub3c4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uc554 \uce58\ub8cc\uc81c\ub85c \uc798\ubabb \uc120\uc804\ub418\uae30\ub3c4 \ud588\uc2b5\ub2c8\ub2e4. 1965\ub144 \ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(FDA)\uc740 DMSO\uac00 \uc2e4\ud5d8 \ub3d9\ubb3c \uc548\uacbd \ub80c\uc988\uc758 \uad74\uc808\ub960\uc744 \ubcc0\uacbd\ud588\uae30 \ub54c\ubb38\uc5d0 \uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c DMSO\uc758 \uc0ac\uc6a9\uc744 \uae08\uc9c0\ud588\uc2b5\ub2c8\ub2e4. \uae08\uc9c0\ub839\uc740 \uc774 \ubb3c\uc9c8\uc5d0 \ub300\ud55c \uad00\uc2ec\uc774 \uc1e0\ud1f4\ud55c \ud6c4 1980\ub144\uc5d0 \ud574\uc81c\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uc5f0\uad6c\uc790\ub4e4\uc740 \uacc4\uc18d\ud574\uc11c DMSO\ub97c \uac00\ub2a5\ud55c \uce58\ub8cc\ubc95\uc73c\ub85c \ubcf4\uace0 \uc788\uc2b5\ub2c8\ub2e4. 2016\ub144\uc5d0 \ube0c\ub9ac\ud2f0\uc2dc \uceec\ub7fc\ube44\uc544 \uc554\uccad(\ubc34\ucfe0\ubc84), \ube0c\ub9ac\ud2f0\uc2dc \uceec\ub7fc\ube44\uc544 \ub300\ud559(\ubc34\ucfe0\ubc84), \ubc34\ucfe0\ubc84 \uc885\ud569\ubcd1\uc6d0\uc758 GeraldKrystal\uacfc \ub3d9\ub8cc\ub4e4\uc740 DMSO\uac00 \uc778\uac04 \ud608\uc561 \uc138\ud3ec\uc5d0\uc11c \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc758 \uc0dd\uc131\uc744 \uc5b5\uc81c\ud558\uc5ec \uc790\uac00\uba74\uc5ed \uad00\uc808\uc5fc\uc744 \uac10\uc18c\uc2dc\ud0a8\ub2e4\uace0 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \uc800\uc790\ub294 \ub610\ud55c DMSO\uc5d0 \ud56d\uc554 \ud65c\uc131\uc774 \uc788\ub294\uc9c0 \uc870\uc0ac\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uc774\uac83\uc774 \uc0ac\uc2e4\uc778\uc9c0 \ud655\uc778\ud560 \uc218 \uc5c6\ub2e4\uace0 \uacb0\ub860\uc9c0\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\ub514\uba54\ud2f8\uc124\ud3ed\uc0ac\uc774\ub4dc \uc704\ud5d8 \uc815\ubcf4<\/p>\n<p>\uc704\ud5d8 \uc218\uc900 * GHS \ucf54\ub4dc \ubc0f \uc704\ud5d8 \uc124\uba85<\/p>\n<p>\uc778\ud654\uc131 \uc561\uccb4, \ud074\ub798\uc2a4 4 H227 \u2013 \uc778\ud654\uc131 \uc561\uccb4<\/p>\n<p>* \uc138\uacc4\uc801\uc73c\ub85c \uc870\ud654\ub41c \ud654\ud559\ubb3c\uc9c8 \ubd84\ub958 \ubc0f \ud45c\uc2dc \uc2dc\uc2a4\ud15c(GHS).<\/p>\n<p>\ubbf8\ub798\uc758 \ubd84\uc790<\/p>\n<p>Emmanuelle Echarpentier\uc640 JenniferDoudna\uac00 2020\ub144 \ub178\ubca8 \ud654\ud559\uc0c1\uc744 \uc218\uc0c1\ud55c CRISPR-Cas9 \uac8c\ub188 \ud3b8\uc9d1 \uc2dc\uc2a4\ud15c\uc740 \uc0dd\ubb3c\ud559\uc5d0 \ud601\uba85\uc744 \uc77c\uc73c\ucf30\uc2b5\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \uc0dd\uac01\ub9cc\ud07c \ud6a8\uacfc\uc801\uc774\uc9c0\ub294 \uc54a\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc138\ud3ec\uc758 \uae30\uc874 DNA\uc758 \ud45c\uc801 \ubd80\uc704\uc5d0 \uc0c8\ub85c\uc6b4 DNA \uc870\uac01\uc744 \uc0bd\uc785\ud558\ub294 \uc2dc\uac04\uc774 20% \ubbf8\ub9cc\uc778\ub370, \uc774\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uc0bd\uc785\uc774 \uc644\ub8cc\ub418\uae30 \uc804\uc5d0 \uc138\ud3ec\uac00 \ud30c\uc190\ub41c \ubd80\ubd84\uc744 \ubcf5\uad6c\ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n<p>\uc9c0\ub09c \ub2ec ACS \uc804\uad6d \ud68c\uc758\uc5d0\uc11c \ubcf4\uace0\ub41c \ubc14\uc640 \uac19\uc774, \ucc44\ud50c \ud790\uc5d0 \uc788\ub294 \ub178\uc2a4\uce90\ub864\ub77c\uc774\ub098 \ub300\ud559\uad50\uc758 LindseyJames*\uc640 CarolineFoley\ub294 \uc2e0\uc18d\ud55c DNA \ubcf5\uad6c\ub97c \ucd09\uc9c4\ud558\ub294 \ub2e8\ubc31\uc9c8\uc758 \uc791\uc6a9\uc744 \ucc28\ub2e8\ud558\ub294 \ubd84\uc790\ub97c \ucc3e\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\uc9c4\uc740 \ube0c\ub85c\ubaa8\ubca4\uc790\ubbf8\ub4dc \uc720\ub3c4\uccb4\uc778 UNC21701(\uadf8\ub9bc \ucc38\uc870)\ub85c \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc5b4\ub290 \uc815\ub3c4 \uac00\ub2a5\uc131\uc744 \ubcf4\uc600\uc9c0\ub9cc p53 \uacb0\ud569 \ub2e8\ubc31\uc9c8 1(53BP1) \ub2e8\ubc31\uc9c8\uc5d0 \ub300\ud55c \uce5c\ud654\ub825\uc774 \ub0ae\uc544 \ubd80\ubd84\uc801\uc778 \ud574\uacb0\ucc45\uc5d0 \ubd88\uacfc\ud588\uc2b5\ub2c8\ub2e4.<\/p>","protected":false},"excerpt":{"rendered":"<p>Dimethyl sulfoxide (DMSO) is a widely used solvent that is miscible with water and a variety of organic solvents. It goes by several names, including methylsulfoxide, sulfinyl dimethane and dozens of trade names. DMSO was first discovered in the late 19th century as a byproduct of the craft paper process used to make paper from wood pulp. Around the same time, Russian chemist AlexanderZaytsev synthesized it by oxidizing dimethyl sulfide, another byproduct of the craft paper process. The synthesis of Zaytsev was the basis for the manufacturing process still in use today. DMSO is a laboratory and industrial solvent for many gases, synthetic fibers, paints, hydrocarbons, salts, and natural products. Because it is aprotic, relatively inert, non-toxic, and stable at high temperatures, it is a common solvent for chemical reactions. Its deuterated form is an ideal solvent for nuclear magnetic resonance spectroscopy. In the 1960s, scientists observed that DMSO penetrated\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[35],"attr":[],"class_list":["post-378","post","type-post","status-publish","format-standard","hentry","category-problems","tag-dmso-solvent"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=378"}],"version-history":[{"count":5,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/378\/revisions"}],"predecessor-version":[{"id":1265,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/378\/revisions\/1265"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=378"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=378"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=378"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=378"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}