{"id":2254,"date":"2024-07-31T16:50:41","date_gmt":"2024-07-31T08:50:41","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=2254"},"modified":"2024-07-31T16:50:41","modified_gmt":"2024-07-31T08:50:41","slug":"use-of-dmso-in-drug-preparation","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/use-of-dmso-in-drug-preparation\/","title":{"rendered":"use of dmso in drug preparation"},"content":{"rendered":"

Dimethyl sulfoxide (\u200cDMSO) \u200c is widely used in drug preparation, \u200c mainly includes improving solubility and permeability of drugs, \u200c developing new routes of drug delivery, \u200c increasing local drug content and reducing side effects of drugs. \u200c<\/p>\n

As a weak oxidizing agent, \u200c is soluble and permeable to many drugs, \u200c which makes DMSO an important solvent in drug preparation. \u200cDMSO itself also has anti-inflammatory, \u200c analgesic, \u200c promote blood circulation and wound healing, \u200c diuretic and sedative effects, \u200c can increase drug absorption and improve curative effect. \u200c When the drug is dissolved in DMSO, \u200c does not need to be taken orally or injected, \u200c can be directly applied on the skin to penetrate into the body, \u200c not only opens up a new way of drug delivery, \u200c but also increases the local drug content in the disease area, \u200c reduces the harm to other parts of the body. \u200c In addition, \u200cDMSO has the property of dissolving keratin, \u200c makes it have remarkable effect in improving the therapeutic effect of drugs, \u200c especially in inhibiting the growth of tumor. \u200c<\/p>\n

\"dmso\"<\/p>\n

There are various production methods for DMSO, \u200c including methanol carbon disulfide process, \u200c hydrogen peroxide process, \u200c nitrogen dioxide process, etc. \u200c these methods provide possibilities for large-scale production of DMSO. \u200c The refining methods include vacuum distillation, \u200c and CaH2 heating, \u200c molecular sieve dehydration, \u200c to ensure the purity and quality of DMSO. \u200c<\/p>\n

Despite the many advantages of DMSO, \u200c, there are also safety precautions that need to be taken during use. \u200c should be avoided long-term skin contact with DMSO, \u200c because of its small molecular weight, \u200c easily absorbed through the skin, \u200c may lead to local skin irritation, \u200c itching, \u200c burning sensation. \u200c At the same time, \u200c should also avoid inhaling DMSO, \u200c to avoid nausea, \u200c vomiting and other uncomfortable symptoms. \u200c<\/p>\n

The application of DMSO in drug preparation not only improves the solubility and permeability of the drug, \u200c opens up a new route of drug delivery, \u200c but also increases the local drug content in the disease area and \u200c reduces the side effects of the drug on the body. \u200c However, \u200c requires safety precautions during use and \u200c to avoid possible side effects. \u200c
The role of dimethyl sulfoxide in pharmaceutical
Colorless viscous liquid. Flammable, almost odorless, bitter, hygroscopic. In addition to petroleum ether, it can dissolve general organic solvents.
Strong hygroscopic, at 20 \u00b0 C, when the relative humidity is 60%, it can absorb 70% of its own weight from the air. The product is a weak oxidizing agent, and the non-aqueous dimethyl sulfoxide is non-corrosive to metals.
DMSO\ub294 \ub9ce\uc740 \uc57d\ubb3c\uc5d0 \uc6a9\ud574\uc131 \ubc0f \ud22c\uacfc\uc131\uc744 \uac00\uc9c0\uba70 \ud56d\uc5fc\uc99d\uc131, \uc9c4\ud1b5\uc131, \ud608\uc561\uc21c\ud658 \ucd09\uc9c4 \ubc0f \uc0c1\ucc98\uce58\uc720 \ucd09\uc9c4, \uc774\ub1e8 \ubc0f \uc9c4\uc815 \ud6a8\uacfc\uac00 \uc788\uc73c\uba70 \uc57d\ubb3c \ud761\uc218\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 \uce58\ub8cc \ud6a8\uacfc\ub97c \ud5a5\uc0c1\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc57d\ubb3c\uc740 DMSO\uc5d0 \uc6a9\ud574\ub418\uc5b4 \ud53c\ubd80\uc5d0 \ubc14\ub974\uba74 \uacbd\uad6c\ud22c\uc5ec\ub098 \uc8fc\uc0ac \uc5c6\uc774 \uc778\uccb4\uc5d0 \uce68\ud22c\ud560 \uc218 \uc788\uc5b4 \uc0c8\ub85c\uc6b4 \uc57d\ubb3c \uc804\ub2ec\uc758 \uae38\uc744 \uc5f4\uc5c8\uc73c\uba70, \ub354 \uc911\uc694\ud55c \uac83\uc740 \uc9c8\ubcd1 \ubd80\uc704\uc758 \uad6d\uc18c \uc57d\ubb3c \ud568\ub7c9\uc744 \ub192\uc774\uace0 \uc720\ud574\uc131\uc744 \uc904\uc774\ub294 \uac83\uc785\ub2c8\ub2e4. \uc2e0\uccb4\uc758 \ub2e4\ub978 \uae30\uad00\uc5d0 \uc788\ub294 \uc57d\ubb3c.<\/p>","protected":false},"excerpt":{"rendered":"

Dimethyl sulfoxide (\u200cDMSO) \u200c is widely used in drug preparation, \u200c mainly includes improving solubility and permeability of drugs, \u200c developing new routes of drug delivery, \u200c increasing local drug content and reducing side effects of drugs. \u200c As a weak oxidizing agent, \u200c is soluble and permeable to many drugs, \u200c which makes DMSO an important solvent in drug preparation. \u200cDMSO itself also has anti-inflammatory, \u200c analgesic, \u200c promote blood circulation and wound healing, \u200c diuretic and sedative effects, \u200c can increase drug absorption and improve curative effect. \u200c When the drug is dissolved in DMSO, \u200c does not need to be taken orally or injected, \u200c can be directly applied on the skin to penetrate into the body, \u200c not only opens up a new way of drug delivery, \u200c but also increases the local drug content in the disease area, \u200c reduces the harm to other parts\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"attr":[23],"class_list":["post-2254","post","type-post","status-publish","format-standard","hentry","category-problems"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2254","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=2254"}],"version-history":[{"count":1,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2254\/revisions"}],"predecessor-version":[{"id":2256,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2254\/revisions\/2256"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=2254"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=2254"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=2254"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=2254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}