{"id":2245,"date":"2024-07-31T15:42:59","date_gmt":"2024-07-31T07:42:59","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=2245"},"modified":"2024-07-31T16:06:07","modified_gmt":"2024-07-31T08:06:07","slug":"dmso-solubility","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/dmso-solubility\/","title":{"rendered":"dmso solubility"},"content":{"rendered":"

Dimethyl sulfoxide (DMSO) is a sulfur-containing organic compound, colorless odorless transparent liquid at room temperature, and a hygroscopic flammable liquid. With high polarity, high boiling point, good thermal stability, aprotic, and water miscible characteristics, can dissolve in ethanol, propanol, benzene and chloroform and other most organic matter, known as “universal solvent”.
DMSO (dimethyl sulfoxide) is a polar solvent with excellent solubility. DMSO can dissolve a variety of organic and inorganic compounds at room temperature, such as chlorides, nitrates, sulfates, etc., and can also dissolve some polymer compounds.<\/p>\n

\"dmso
The solubility of DMSO is affected by many factors, including temperature, solvent purity, solute type and concentration. At room temperature, the organic matter dissolved by DMSO is usually in the range of 0.1 ~10g\/100mL, while the inorganic salt solubility is low.
The solubility of DMSO is also related to the pH value of the solution. When the pH value is low, the solubility of DMSO will be reduced, and when the pH value is high, the solubility of DMSO will be increased.
It should be noted that DMSO may have toxic effects on biological systems at high concentrations, so it is necessary to exercise caution when using DMSO and comply with relevant safety regulations.
The solution concentration of \u200c of DMSO (\u200c DSO) is a key parameter. \u200c has a wide range of applications, including \u200c as a cryoprotectant, \u200c as a solvent and in some chemical experiments. The physical properties of \u200cDMSO include a melting point of 18.4\u2103, a boiling point of \u200c of 189\u2103, a density of \u200c of 1.100 kg\/m\u00b3, \u200c and almost odorless, \u200c has a slightly bitter taste. \u200c It is a colorless viscous transparent oily liquid or crystal \u200c having a weak basic character. \u200cDMSO solubility is very good, \u200c can be dissolved in water, \u200c ethanol, \u200c acetone, \u200c benzene and so on. \u200c<\/p>\n

The concentration of \u200cDMSO has a direct effect on cell survival and toxicity during cell culture and freezing. \u200c For example, \u200c \u200cDMSO is commonly used in a 10% concentration during cell freezing, \u200c as a cryoprotectant to prevent the formation of intracellular\/extracellular crystals. \u200c For most cell lines, \u200c0.5% DMSO concentration is considered safe, \u200c while higher concentrations of DMSO (\u200c such as 5%) \u200c although can be applied to some cells, \u200c is usually not recommended, \u200c because it may have toxic effects on cells. \u200c For practical use, the final concentration of \u200cDMSO should be kept below 0.5%, \u200c despite being 200 times more soluble in 100% DMSO when stored. \u200c
DMSO is also used as a stable solvent for the synthesis of organic polymers \u200c its weak alkalinity and good solubility make it a versatile chemical reagent. \u200c<\/p>","protected":false},"excerpt":{"rendered":"

Dimethyl sulfoxide (DMSO) is a sulfur-containing organic compound, colorless odorless transparent liquid at room temperature, and a hygroscopic flammable liquid. With high polarity, high boiling point, good thermal stability, aprotic, and water miscible characteristics, can dissolve in ethanol, propanol, benzene and chloroform and other most organic matter, known as “universal solvent”.DMSO (dimethyl sulfoxide) is a polar solvent with excellent solubility. DMSO can dissolve a variety of organic and inorganic compounds at room temperature, such as chlorides, nitrates, sulfates, etc., and can also dissolve some polymer compounds. The solubility of DMSO is affected by many factors, including temperature, solvent purity, solute type and concentration. At room temperature, the organic matter dissolved by DMSO is usually in the range of 0.1 ~10g\/100mL, while the inorganic salt solubility is low.The solubility of DMSO is also related to the pH value of the solution. When the pH value is low, the solubility of DMSO\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"attr":[23],"class_list":["post-2245","post","type-post","status-publish","format-standard","hentry","category-problems"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=2245"}],"version-history":[{"count":4,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2245\/revisions"}],"predecessor-version":[{"id":2250,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/2245\/revisions\/2250"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=2245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=2245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=2245"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=2245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}