{"id":1953,"date":"2024-06-27T16:42:58","date_gmt":"2024-06-27T08:42:58","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=1953"},"modified":"2024-06-27T16:59:17","modified_gmt":"2024-06-27T08:59:17","slug":"universal-solvent-dmso-2","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/universal-solvent-dmso-2\/","title":{"rendered":"\ubc94\uc6a9 \uc6a9\ub9e4 DMSO"},"content":{"rendered":"

DMSO\uc758 \uc54c\ub824\uc9c0\uc9c0 \uc54a\uc740 \uc5bc\uad74
\uccab\uc9f8, \uc218\uc0b0\uae30 \uc0b0\ud654 \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\uc2ed\uc2dc\uc624.
DMSO\uc640 \uad00\ub828\ub41c \ub450 \uac00\uc9c0 \uc798 \uc54c\ub824\uc9c4 \uc0b0\ud654 \ubc18\uc751\uc740 swern \uc0b0\ud654\uc640 Pfitzner-Moffatt \uc0b0\ud654\uc774\uba70, \ub458 \ub2e4 \uc54c\ucf54\uc62c\uc744 \uc54c\ub370\ud788\ub4dc \ub610\ub294 \ucf00\ud1a4\uc73c\ub85c \u200b\u200b\uc0b0\ud654\uc2dc\ud0a4\ub294 \ub370 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \uadf8 \uc911 \uc625\uc0b4\ub85c\uc77c \ud074\ub85c\ub77c\uc774\ub4dc\uc640 \ud611\ub825\ud558\uc5ec swern\uc758 \uc0b0\ud654\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \ud3ed\ubc1c \uc704\ud5d8\uc744 \ud53c\ud558\uae30 \uc704\ud574 -78\u00b0C\uc5d0\uc11c \uc5fc\ud654\uba54\ud2f8\ub80c\uacfc \ubc18\uc751\ud569\ub2c8\ub2e4(DOI:10.1021\/jo00882a030). \ubc18\uba74, Pfitzner-Moffatt \uc0b0\ud654\ub294 3\ub2f9\ub7c9 \uc774\uc0c1\uc758 DCC\uc640 \uac15\uc0b0\uc131 \uc870\uac74\uc744 \uc0ac\uc6a9\ud558\uc5ec DMSO\ub97c \ud65c\uc131\ud654\ud558\uc5ec \uc0b0\ud654\ub97c \ub2ec\uc131\ud569\ub2c8\ub2e4(DOI:10.1021\/ja00952a026).
\"Participation
\ub458\uc9f8, \uc694\uc624\ub4dc \uc0b0\ud654 \uc7ac\ubc30\uc5f4\uc5d0 \ud611\ub825
2023\ub144 \ubd81\uacbd\ub300\ud559\uad50 Jiao Ning \uad50\uc218 \uc5f0\uad6c \uadf8\ub8f9\uc740 DMSO\uc640 \uc0ac\uc774\ud074\ub85c\ubd80\ud14c\ub17c\uc758 \uc0c8\ub85c\uc6b4 \uc694\uc624\ub4dc \ucd09\ub9e4 \uc0b0\ud654 \uc7ac\ubc30\uc5f4\uc744 \ubcf4\uace0\ud558\uc5ec \uc77c\ub828\uc758 \ud478\ub780-2(5H)-\ucf00\ud1a4 \ubd84\uc790 \uad6c\uc131\uc744 \uc131\uacf5\uc801\uc73c\ub85c \uc644\ub8cc\ud588\uc2b5\ub2c8\ub2e4. \ubcf8 \ubc18\uc751\uc5d0\uc11c\ub294 MeNO2 \ubc18\uc751\uc6a9\ub9e4\uc5d0 \uc694\uc624\ub4dc\ub97c \ucd09\ub9e4\ub85c \uc0ac\uc6a9\ud558\uc600\uc73c\uba70, \ubc18\uc751\uc628\ub3c4\ub294 100\u2103, \ucd5c\uc885 \uc0dd\uc131\ubb3c \uc218\uc728\uc740 84%\uc774\uc5c8\ub2e4. \ub2c8\ud2b8\ub85c\uba54\ud0c4 \uc790\uccb4\ub294 \ub354 \uc704\ud5d8\ud569\ub2c8\ub2e4. Jiao\uc758 \uc870\uac74\ubd80 \uc2ec\uc0ac\uc5d0\uc11c\ub294 \ud1a8\ub8e8\uc5d4\uc774 75% \uc218\uc728\ub85c \ud574\ub2f9 \uc81c\ud488\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\ub2e4\uace0 \uc5b8\uae09\ud588\uc2b5\ub2c8\ub2e4. \ub2c8\ud2b8\ub85c\uba54\ud0c4\uc744 \ud53c\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4(doi:10.1039\/D3GC01756G).
\"Details
3. \uc544\ub9b4 \ud074\ub85c\ub77c\uc774\ub4dc\ub97c \ucd09\ub9e4\ud569\ub2c8\ub2e4.
Junning \uad50\uc218\uc758 \ub3d9\uc77c\ud55c \ud300\uc740 DMSO\uc640 \ud568\uaed8 \uc5fc\uc18c\ud654 \uc2dc\uc57d NCS\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc77c\ub828\uc758 (\ud558\uc774\ube0c\ub9ac\ub4dc) \ubc29\ud5a5\uc871 \ud0c4\ud654\uc218\uc18c\uc758 C-H \uacb0\ud569 \uc5fc\uc18c\ud654\ub97c 2020\ub144 NatureCatalytic\uc5d0 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. \ubc18\uc751\uc740 \uc2e4\uc628\uc5d0\uc11c \uc131\uacf5\uc801\uc73c\ub85c \uc644\ub8cc\ub420 \uc218 \uc788\uc73c\uba70 \ub2e8\uc21c\ud55c \ubd84\uc790\ubfd0\ub9cc \uc544\ub2c8\ub77c \ubcf5\uc7a1\ud55c \ucc9c\uc5f0\ubb3c, \uc57d\ubb3c \ubd84\uc790 \ubc0f \ud3a9\ud0c0\uc774\ub4dc\uc758 \ud6c4\uae30 \ubcc0\ud615\uc5d0\ub3c4 \uc801\ud569\ud569\ub2c8\ub2e4. \ubc18\uc751\uc740 \uc2e4\uc628\uc758 \ud074\ub85c\ub85c\ud3ec\ub984 \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uc218\ud589\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4(doi.org\/10.1038\/s41929-019-0398-0).<\/p>\n

4. \uc694\uc624\ub4dc\uc640 \ud611\ub825\ud558\uc5ec \ubd84\uc790 \ub0b4 C-H \ubc0f N-H \ud65c\uc131\ud654 \uacb0\ud569\uc744 \ucd09\ub9e4\ud569\ub2c8\ub2e4.
2021\ub144 \uc911\uad6d \uc0bc\ud611\ub300\ud559\uad50 Zhou Haifeng \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \uac04\ub2e8\ud55c \ucd09\ub9e4 \uc2dc\uc2a4\ud15c\uc758 \ubd84\uc790 \ub0b4 C(sp3)-H\/N-H \uc0b0\ud654 \uad50\ucc28 \uacb0\ud569 \ubc18\uc751\uc744 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc5d0\uc11c\ub294 2-(\ubca4\uc9c8 \uc544\ubbf8\ub178) \ubca4\uc988\uc544\ubbf8\ub4dc \ud654\ud569\ubb3c\uc744 \uc6d0\ub8cc\ub85c \uc0ac\uc6a9\ud558\uc5ec I2\/DMSO \ub9e4\uac1c \ubd84\uc790\ub0b4 \uc0b0\ud654 \uad50\ucc28 \uacb0\ud569\uc744 \ud1b5\ud574 CN \uacb0\ud569\uc744 \ud615\uc131\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc6b0\uc218\ud55c \uad00\ub2a5\uae30 \ub0b4\uc131\uacfc \ub192\uc740 \uc218\uc728\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud569\ub2c8\ub2e4. \ub610\ud55c, \uadf8\ub7a8 \uaddc\ubaa8 \ubc18\uc751 \ubc29\ubc95 \uc5ed\uc2dc 90% \uc774\uc0c1\uc758 \uc218\uc728\uc744 \uc5bb\uc744 \uc218 \uc788\ub2e4(DOI: 10.1002 \/ ejoc. 202101187).
\uc694\uc624\ub4dc\uc640 \uc870\ud654\ub97c \uc774\ub8e8\ub294 C-H,N-H \ud65c\uc131\ud654\uc758 \uc0c1\uc138\ud55c \ucee4\ud50c\ub9c1.png
\ud53c\ub9ac\ubbf8\ub518 \uace0\ub9ac \ud569\uc131\uc5d0 \uad00\uc5ec\ud558\ub294 DMSO\uc758 \ud65c\uc131\ud654
2020\ub144\uc5d0 \uc548\ud6c4\uc774 \ub18d\uc5c5 \ub300\ud559\uad50\uc758 Tao-ShanJiang \ud300(\ucc3e\uc744 \uc218 \uc5c6\ub294 \uacbd\uc6b0, \uc791\uc740 \uc2dc\ub9ac\uc988\uc5d0 \uc54c\ub9b4 \uc218 \uc788\uc74c)\uc740 \ud65c\uc131\ud654\ub41c DMSO\ub97c \uc0ac\uc6a9\ud558\uc5ec \ud53c\ub9ac\ubbf8\ub518 \uace0\ub9ac \ud569\uc131\uc744 \uc644\ub8cc\ud558\ub294 \ubc29\ubc95\uc744 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \uc544\ubbf8\ub518 \uc5fc\uc0b0\uc5fc, \ucf00\ud1a4 \ubc0f \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc\ub97c \uc0ac\uc6a9\ud558\uc5ec \uae30\uc9c8 \uc720\ub3c4 \ub514\uba54\ud2f8 \uc124\ud3ec\uc77c \ud65c\uc131\ud654 \ubc0f \ud6c4\uc18d \ubc18\uc751\uc744 \ud1b5\ud574 \ud53c\ub9ac\ubbf8\ub518\uc744 \uc9c1\uc811 \ud569\uc131\ud569\ub2c8\ub2e4. \uc774 \uacc4\ud68d\uc5d0\uc11c \uc544\ubbf8\ub518 \uc5fc\uc0b0\uc5fc\uc740 \ubc18\uc751\ubb3c\ub85c \uc0ac\uc6a9\ub420 \ubfd0\ub9cc \uc544\ub2c8\ub77c \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc\ub97c \ud65c\uc131\ud654\ud558\uc5ec \ud2f0\uc624\ub098\uc774\ud2b8 \uc911\uac04\uccb4\ub97c \ud615\uc131\ud55c \ub2e4\uc74c \ubc18\uc751\uc5d0 \ucc38\uc5ec\ud558\uc5ec \ud53c\ub9ac\ubbf8\ub518 \ud569\uc131\uc744 \uc644\ub8cc\ud569\ub2c8\ub2e4(DOI:10.1039\/d0qo01416h).<\/p>\n

6. \ucf54\ubc1c\ud2b8\uac00 \ucd09\ub9e4\ud558\ub294 \ud034\ub180\ub9b0\uc758 \uace8\uaca9 \ud569\uc131\uc5d0 \ucc38\uc5ec
2017\ub144 \uad11\uc800\uc6b0 \uc758\uacfc\ub300\ud559 Yi Wei \uad50\uc218\ud300\uc740 \ud2b9\ubcc4 \ud034\ub180\ub9b0\uc758 \uc9c1\uc811\uc801\uc774\uace0 \ud6a8\uc728\uc801\uc778 \ud569\uc131\uc744 \uc704\ud574 \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc\uc758 \ucc38\uc5ec\ub85c \uc544\ub2d0\ub9b0\uacfc \uc54c\ud0a8\uc758 \uac04\ub2e8\ud558\uace0 \uc800\ub834\ud558\uba70 \uc27d\uac8c \uc774\uc6a9 \uac00\ub2a5\ud55c C\u2212H \ud65c\uc131\ud654\/\uace0\ub9ac\ud654\ub97c \ucd09\ub9e4\ud558\ub294 \ub3c5\ud2b9\ud55c Co(III)\ub97c \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \ub3c5\uc810\uc801\uc778 \uc9c0\uc5ed \uc120\ud0dd\uc131\uacfc \ub113\uc740 \uae30\uc9c8\/\uad00\ub2a5\uae30 \ub0b4\uc131\uc744 \uac00\uc9c0\uba70 \uc6b0\uc218\ud55c \uc218\uc728\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub514\uba54\ud2f8 \uc5d0\ud14c\ub974\ub294 \ud034\ub180\ub9b0 \uc81c\ud488\uc758 \uc6a9\ub9e4 \ubc0f C1 \ube4c\ub529 \uadf8\ub8f9\uc73c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc\uc758 \uba54\ucee4\ub2c8\uc998\uc740 \ubc18\uc751\uc774 \ub2e4\uae30\ub2a5 2-\ube44\ub2d0 \uc544\ub2d0\ub9b0 \uc885\uc744 \ubc18\uc751\uc131 \uc911\uac04\uccb4\ub85c \ucc44\ud0dd\ud560 \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4(DOI:10.1021\/acs.org lett. 7 b03673).<\/p>\n

7, \uba54\ud2f8 \ud2f0\uc624\uba54\ud2f8 \uc5d0\uc2a4\ud14c\ub974 \ub610\ub294 \uba54\ud2f8 \uc5d0\ud14c\ub974\uc758 \ud569\uc131\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4.
2022\ub144 \uad6c\uc774\uc800\uc6b0 \uc758\uacfc\ub300\ud559 \uc591\uc0e4\uc624\uc131 \uad50\uc218\ud300\uc740 DMSO\ub97c \uc774\uc6a9\ud574 \uba54\ud2f8\ud2f0\uc624\uba54\ud2f8\uc5d0\uc2a4\ud14c\ub974\ub098 \uba54\ud2f8\uc5d0\ud14c\ub974\ub97c \ud569\uc131\ud558\ub294 \ubc29\ubc95\uc744 \ubcf4\uace0\ud588\ub2e4. \uc774\ub294 \uc6a9\ub9e4 \ubc0f \uba54\ud2f0\uc624\ub2d0 \uacf5\uae09\uc6d0\uc778 \uce74\ub974\ubcf5\uc2e4\uc0b0\/\ud398\ub180 \ubc0f \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc(DMSO)\ub85c\ubd80\ud130 \uc9c1\uc811 \uba54\ud2f0\uc624\ub2d0 \uc5d0\uc2a4\ud14c\ub974\/\uc5d0\ud14c\ub974\ub97c \uc81c\uc870\ud558\ub294 \ub370 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\uc591\ud55c \uc720\ud615\uc758 \uce74\ub974\ubcf5\uc2e4\uc0b0\/\ud398\ub180\uc758 \uacbd\uc6b0 \ubc18\uc751\uc774 \uc6d0\ud65c\ud558\uac8c \uc9c4\ud589\ub418\uc5b4 \uc0c1\uc751\ud558\ub294 MTM \uc5d0\uc2a4\ud14c\ub974\/\uc5d0\ud14c\ub974\ub97c \uc801\ub2f9\ud55c \uc218\uc728\uc5d0\uc11c \uc6b0\uc218\ud55c \uc218\uc728\ub85c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \ucd09\ub9e4\uac00 \uc5c6\uace0, \uc791\ub3d9\uc774 \uc27d\uace0, \uae30\uc9c8\uc774 \uad11\ubc94\uc704\ud558\uace0, \uad00\ub2a5\uae30 \ub0b4\uc131\uc774 \ub6f0\uc5b4\ub098\uba70, \ub514\uba54\ud2f8 \uc124\ud3ed\uc0ac\uc774\ub4dc \uc5d0\ub180\ud654 \ud568\ub7c9 \ubc0f \uae30\ud0c0 \ud2b9\uc131\uc758 \ud615\uc131\uc5d0 \ucc38\uc5ec\ud569\ub2c8\ub2e4(doi.org\/10.1039\/D2RA06618A).<\/p>\n

8, \uad50\ucc28 \ud0c8\uc218\uc18c\ud654\ub97c \uc644\ub8cc\ud558\uae30 \uc704\ud574 NBS\uc640 \uce74\ub974\ubcf5\uc2e4\uc0b0\uc758 \uc791\uc6a9\ud558\uc5d0
2020\ub144\uc5d0 \uc2e0\uc591 \uc0ac\ubc94\ub300\ud559\uad50 Tang Lin \uad50\uc218 \ud300\uc740 Pummerer\ud615 \uc7ac\ubc30\uc5f4\uc744 \ud1b5\ud574 \uacf5\uc2dd\uc801\uc778 C-O \uacb0\ud569 \ud615\uc131\uc744 \ucd09\uc9c4\ud558\ub294 NBS\ub97c \uc0ac\uc6a9\ud558\uc5ec DMSO\ub97c \uc0ac\uc6a9\ud55c \uce74\ub974\ubcf5\uc2e4\uc0b0\uc758 \uc804\uc774\uae08\uc18d \uc5c6\ub294 \uad50\ucc28 \ud0c8\uc218\uc18c\ud654\ub97c \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc804\ud658\uc740 \uc628\ud654\ud55c \uc870\uac74\uc5d0\uc11c \uc27d\uac8c \uc0ac\uc6a9\ud560 \uc218 \uc788\ub294 \uce74\ub974\ubcf5\uc2e4\uc0b0\uc744 \uce5c\ud575\uccb4\ub85c \uc0ac\uc6a9\ud558\uace0 DMSO\ub97c \uc2e0 \ud568\uc720 \ud0c4\uc18c\uc6d0 \ubc0f \uc6a9\ub9e4\ub85c \uc0ac\uc6a9\ud558\uc5ec \uad11\ubc94\uc704\ud55c \uae30\uc9c8\uacfc \ud568\uaed8 \uac00\uce58 \uc788\ub294 \uba54\ud2f8 \uc5d0\uc2a4\ud14c\ub974\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \ub610\ud55c, \uc774 \uacc4\ud68d\uc740 \uba54\ud2f8 \uc911\uc218\uc18c \uc0dd\uc131\uc758 \uc2dc\uc57d \uc81c\uc81c\ub85c\uc11c \uc911\uc218\uc18c \ud45c\uc9c0 DMSO\ub97c \uc0ac\uc6a9\ud558\uc5ec \ud6a8\uacfc\uc801\uc774\uace0 \uc9c1\uc811\uc801\uc778 \ubc29\ubc95\uc73c\ub85c \uac1c\ubc1c\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4(doi.org\/10.1039\/D0QO00617C).<\/p>\n

9. \uc0b0\uc18c\uc6d0\uc778 \uc62c\ub808\ud540\uc758 \uc694\uc624\ub3c4\uc218\uc0b0\ud654 \ubc18\uc751\uc5d0 \ucc38\uc5ec
2017\ub144 Jiao Ning \uad50\uc218 \uc5f0\uad6c\ud300\uc740 \uac12\uc2fc \uc694\uc624\ub4dc\ud654\ubb3c\uacfc \uc77c\ubc18 \uc6a9\ub9e4 DMSO\ub97c \uc0b0\ud654\uc81c\ub85c \uc0ac\uc6a9\ud558\ub294 \uc62c\ub808\ud540\uc758 \uc0b0\ud654 \uc694\uc624\ub3c4\uc218\uc0b0\ud654 \ubc18\uc751\uc744 \ubcf4\uace0\ud558\uc5ec \uc694\uc624\ub3c4\uc54c\ucf54\uc62c \ud569\uc131\uc744 \uc704\ud55c \uc0c8\ub85c\uc6b4 \ubc29\ubc95\uc744 \uc81c\uc2dc\ud588\uc2b5\ub2c8\ub2e4. DMSO\ub294 \uc0b0\ud654\uc81c, \uc6a9\ub9e4 \ubc0f \uc0b0\uc18c \uacf5\uae09\uc6d0\uc73c\ub85c \uc791\uc6a9\ud558\uc5ec \uc774 \ubc18\uc751\uc5d0\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc774 \ubc29\ubc95\uc740 \ubcf4\ub2e4 \uce5c\ud575\uc131\uc778 \uc6a9\ub9e4\ub85c \uc804\ud658\ud558\uc5ec \uc62c\ub808\ud540\uc758 \uc694\uc624\ub4dc\uc5d0\ud14c\ub974\ud654\ub97c \uac00\ub2a5\ud558\uac8c \ud569\ub2c8\ub2e4(DOI:10.6023\/a17100448).
\uc0b0\uc18c \uacf5\uae09\uc6d0\uc778 \uc62c\ub808\ud540\uc758 \uc694\uc624\ub4dc\uc218\uc0b0\ud654\uc5d0 \ub300\ud55c \uc138\ubd80 \uc0ac\ud56d.png
DMSO\/KOH\/H2O2\ub294 \uc2dc\uc548\ud654\ubb3c \uadf8\ub8f9\uc744 \uac00\uc218\ubd84\ud574\ud569\ub2c8\ub2e4.
\uc774\uac83\uc740 \uc6b0\ub9ac\uac00 \uc140 \uc218 \uc5c6\uc774 \ub9ce\uc774 \uc778\uc6a9\ud55c DMSO\uc758 \ud2b9\ubcc4\ud55c \uc6a9\ub3c4\uc785\ub2c8\ub2e4. \uc2e4\uc628\uc5d0\uc11c 5~30\ubd84 \ub3d9\uc548 \ubc18\uc751\uc744 \uc644\ub8cc\ud558\uba74 \ub2c8\ud2b8\ub9b4\uc744 \uac00\uc218\ubd84\ud574\ud558\uc5ec \uc544\ubbf8\ub4dc\ub97c \uc81c\uc870\ud558\ub294 \ub9e4\uc6b0 \uc2e4\uc6a9\uc801\uc778 \ubc29\ubc95\uc785\ub2c8\ub2e4. \uc774\uc804 \ud504\ub85c\uc81d\ud2b8\uc5d0\uc11c\ub294 \ub9ce\uc740 \uc2dc\uc544\ub178\uac90 \uac00\uc218\ubd84\ud574 \uacf5\uc815\uc774 \uc774 \ubc29\ubc95\uc744 \ucc44\ud0dd\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uacc4\ud68d\uc740 1989\ub144 SYNTHESIS(DOI:10.1055\/s-1989-27441)\uc5d0 \ucc98\uc74c \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n

\ubb3c\ub860 DMSO\uc758 \ub9c8\ubc95 \uae30\ub2a5\uc740 \uc704\uc758 10\uac00\uc9c0 \uc885\ub958\ubcf4\ub2e4 \ud6e8\uc52c \ub354 \ub9ce\uae30 \ub54c\ubb38\uc5d0 Xiaobian\uc774 \ud2b8\uc717\uc73c\ub85c \ubaa8\ub4e0 \uac83\uc744 \uc18c\uac1c\ud560 \uc218\ub294 \uc5c6\uc73c\ubbc0\ub85c \uc774\ud574\ud558\uc2dc\uae30 \ubc14\ub78d\ub2c8\ub2e4. \uc774\ub7f0 \ubc18\uc751\uc5d0 \ub300\ud574 \ub354 \uae4a\uc774 \uc774\ud574\ud558\uace0 \uc788\ub294 \uc18c\uaddc\ubaa8 \ud30c\ud2b8\ub108\ub294 \uc791\uc740 \uce5c\uad6c\ub97c \ucd94\uac00\ud558\uc5ec \uc18c\ud1b5\ud558\ub294 \uac83\ub3c4 \ud658\uc601\ud569\ub2c8\ub2e4.<\/p>","protected":false},"excerpt":{"rendered":"

The unknown face of DMSOFirst, participate in hydroxyl oxidation reactionTwo well-known oxidation reactions involving DMSO are swern oxidation and Pfitzner-Moffatt oxidation, both of which are used to oxidize alcohols to aldehydes or ketones. Among them, the oxidation of swern in partnership with oxaloyl chloride usually reacts in methylene chloride at -78 \u00b0 C to avoid the risk of explosion (DOI:10.1021\/jo00882a030). Pfitzner-Moffatt oxidation, on the other hand, uses DCC of more than 3 equivalent and strong acidic conditions to activate DMSO to achieve oxidation (DOI:10.1021\/ja00952a026).Second, cooperate with iodine oxidation rearrangementIn 2023, Professor Jiao Ning’s research group at Peking University reported a new iodine-catalyzed oxidative rearrangement of DMSO and cyclobutenones, which successfully completed the construction of a series of furan-2 (5H) -ketone molecules. In this reaction, iodine was used as catalyst in MeNO2 reaction solvent, the reaction temperature was 100\u2103, and finally the product yield was 84%. Nitromethane itself is more dangerous,\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"attr":[23],"class_list":["post-1953","post","type-post","status-publish","format-standard","hentry","category-problems"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=1953"}],"version-history":[{"count":2,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1953\/revisions"}],"predecessor-version":[{"id":1957,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1953\/revisions\/1957"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=1953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=1953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=1953"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=1953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}