{"id":1729,"date":"2024-04-15T16:52:01","date_gmt":"2024-04-15T08:52:01","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=1729"},"modified":"2024-04-15T16:56:31","modified_gmt":"2024-04-15T08:56:31","slug":"pharmaceutical-grade-povidone-k90-features-2024-pharmacopoeia-filing","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/pharmaceutical-grade-povidone-k90-features-2024-pharmacopoeia-filing\/","title":{"rendered":"\uc81c\uc57d \ub4f1\uae09 POvidone K90\uc740 2024\ub144 \uc57d\uc804 \ub4f1\ub85d\uc744 \ud2b9\uc9d5\uc73c\ub85c \ud569\ub2c8\ub2e4."},"content":{"rendered":"

\ud3ec\ube44\ub3c8\uc740 \uc218\uc6a9\uc131 \ud569\uc131 \uace0\ubd84\uc790\ub85c, \ud575\uc2ec \uc131\ubd84\uc740 N-\ube44\ub2d0\ub9ac\ub370\ub17c\uc785\ub2c8\ub2e4. \uc811\ucc29\uc131\uc774 \ub192\uc740 \uace0\ubd84\uc790\ub85c \uace0\ud615\uc81c\uc81c\uc758 \uc2b5\uc2dd\uacfc\ub9bd\ud654\ub97c \uc704\ud55c \uacb0\ud569\uc81c\ub85c \uc911\uc694\ud569\ub2c8\ub2e4. \uadf8 \ud2b9\uc131\uc73c\ub85c \uc778\ud574 \ub2e4\uc591\ud55c \uacbd\uad6c\uc6a9 \uc561\uccb4 \uc2dc\uc2a4\ud15c, \ud604\ud0c1\uc561 \ubc0f \ud604\uc9c0 \uc57d\ubb3c \uac1c\ubc1c \uc751\uc6a9 \ubd84\uc57c\uc5d0\uc11c \uc911\uc694\ud55c \ubd80\ud615\uc81c\uac00 \ub429\ub2c8\ub2e4.
\uc6a9\ud574\ub3c4: \ubb3c \ubc0f \ud560\ub85c\uac90\ud654 \ud0c4\ud654\uc218\uc18c \uc6a9\ub9e4, \uc54c\ucf54\uc62c, \uc544\ubbfc, \ub2c8\ud2b8\ub85c\uc54c\uce78 \ubc0f \uc800\ubd84\uc790 \uc9c0\ubc29\uc0b0\uc5d0 \uc27d\uac8c \uc6a9\ud574\ub418\uba70 \uc544\uc138\ud1a4, \uc5d0\ud2f8, \ud14c\ub808\ube48\uc720, \uc9c0\ubc29\uc871 \ud0c4\ud654\uc218\uc18c \ubc0f \uc9c0\ud658\uc871 \ud0c4\ud654\uc218\uc18c \ubc0f \uae30\ud0c0 \uc18c\uc218\uc758 \uc6a9\ub9e4\uc5d0 \uc6a9\ud574\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub300\ubd80\ubd84\uc758 \ubb34\uae30\uc5fc \ubc0f \ub2e4\uc591\ud55c \uc218\uc9c0\uc640 \uc0c1\uc6a9\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.
\ud2b9\uc131: \uce5c\uc218\uc131\uc774\uba70 \ud750\ub974\uae30 \uc26c\uc6b4 \ud770\uc0c9 \ub610\ub294 \uac70\uc758 \ud770\uc0c9\uc758 \ubd84\ub9d0\uc774\uba70 \uc57d\uac04\uc758 \ub0c4\uc0c8\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n

\"PVP
PVP\ub294 \ud3c9\uade0 \ubd84\uc790\ub7c9 \ud06c\uae30\uc5d0 \ub530\ub77c 4\ub2e8\uacc4\ub85c \ub098\ub258\uba70, \uc774\ub294 \uc77c\ubc18\uc801\uc73c\ub85c K \uac12\uc73c\ub85c \ud45c\uc2dc\ub418\uba70, \uc11c\ub85c \ub2e4\ub978 K \uac12\uc740 PVP\uc758 \ud574\ub2f9 \ud3c9\uade0 \ubd84\uc790\ub7c9 \ubc94\uc704\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. K\uac12\uc740 \uc2e4\uc81c\ub85c PVP \uc218\uc6a9\uc561\uc758 \uc0c1\ub300\uc810\ub3c4\uc640 \uad00\ub828\ub41c \uace0\uc720\uac12\uc774\uace0, \uc810\ub3c4\ub294 \uace0\ubd84\uc790\uc758 \ubd84\uc790\ub7c9\uacfc \uad00\ub828\ub41c \ubb3c\ub9ac\ub7c9\uc774\ubbc0\ub85c PVP\uc758 \ud3c9\uade0\ubd84\uc790\ub7c9\uc740 K\uac12\uc73c\ub85c \ud2b9\uc9d5\uc9c0\uc744 \uc218 \uc788\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c K \uac12\uc774 \ud074\uc218\ub85d \uc810\ub3c4\uac00 \ub192\uc544\uc9c0\uace0 \uc811\ucc29\ub825\uc774 \uac15\ud574\uc9d1\ub2c8\ub2e4. \uc774\uc0b0\ud654\ud2f0\ud0c0\ub284 CAS \ubc88\ud638:13463-67-7 \ubd84\uc790\uc2dd:02Ti \ubd84\uc790\ub7c9:79.87.
\ub514\ubd80\ud2f8\ud788\ub4dc\ub85d\uc2dc\ud1a8\ub8e8\uc5d4 \ubd84\uc790\uc2dd C15H240220.35CAS \ubc88\ud638 [128-37-0]
\ub9cc\ub2c8\ud1a8 CAS \ubc88\ud638:87-78-5; 69-65-8
\ud30c\ub77c\ud540 CAS \ubc88\ud638 :8002-74-2 \ubd84\uc790\uc2dd :CnH2n+2n=24~36 \ubd84\uc790\ub7c9 :0
\uc911\uad6d\uc5b4 \uc2dc\ud074\ub85c\uba54\ud2f8\uc2e4\ub9ac\ucf58 \uc678\uad6d \uc774\ub984 CyclomethiconeCAS \ub4f1\ub85d \ubc88\ud638 69430-24-6EINECS \ubc88\ud638 209-136-7
Xanthangum CAS:11138-66-2 \uc601\ubb38\uba85 : XanthangumEINECS : 234-394-2 \ubd84\uc790\uc2dd : C35H49029
\ubc14\uc140\ub9b0 CAS \ubc88\ud638 :8009-03-8 \ubd84\uc790\uc2dd :C15H15N \ubd84\uc790\ub7c9 :209.2863
\uc778\uc0b0\uc218\uc18c\uc774\uce7c\ub968 CAS \ubc88\ud638: 16788-57-1 \ubd84\uc790\uc2dd:H7K207P \ubd84\uc790\ub7c9:228.22
\uc6b0\ub808\uc544 \ubd84\uc790\uc2dd \ubc0f \ubd84\uc790\ub7c9 CH4N2060.06
\uc544\uc138\ud2b8\uc0b0\ub098\ud2b8\ub968 CAS :6131-90-4 \ubd84\uc790\uc2dd :C2H9Na05 \ubd84\uc790\ub7c9 :136.08
\ubd84\uc790\uc2dd : C57H11006 \ubd84\uc790\ub7c9 : 891.48CAS \ubc88\ud638 : 68334-00-9
DL \ud0c0\ub974\ud0c0\ub974\uc0b0 CAS \ubc88\ud638:133-37-9 \ubd84\uc790\uc2dd:C4H606 \ubd84\uc790\ub7c9:150.09
\ud3f4\ub9ac\uc544\ud06c\ub9b4 \uc218\uc9c0 CAS \ubc88\ud638: 24938-16-7 \ubd84\uc790\uc2dd:(C8H15N02\u00b7C8H1402\u00b7C5H802)x
\uc18c\ub974\ube48\uc0b0 \uce7c\ub968 CAS \ubc88\ud638 :590-00-1 \ubd84\uc790\uc2dd :C6H7K02 \ubd84\uc790\ub7c9 :150.22
\ud3f4\ub9ac\ube44\ub2d0\ud53c\ub864\ub9ac\ub3c8 \ubd84\uc790\uc2dd
(C6H9NO)n
\uc218\ubd84 \ud568\ub7c9 5.0%
\uc9c8\uc18c 12.0~12.8%
\ubd84\uc790\ub7c9 \ud3f4\ub9ac\uc5d0\ud2f8\ub80c \ud53c\ub864\ub9ac\ub3c8 K90
\ud669\uc0b0\ud68c 0.1%
pH \uac12(10% \uc218\uc6a9\uc561)5.0-9.0
\ud3c9\uade0 \ubd84\uc790\ub7c9\uc740 1300000\uc785\ub2c8\ub2e4.
\uc54c\ub370\ud788\ub4dc(\uc544\uc138\ud2b8\uc54c\ub370\ud788\ub4dc)0.05%
\uc911\uae08\uc18d %(Pb)10ppm
CASNo 9003-39-8
\ud788\ub4dc\ub77c\uc9c4(PPM)1.0%
\uacfc\uc0b0\ud654\ubb3c(PPM, \uacfc\uc0b0\ud654\uc218\uc18c \uc911)400
K \ubc94\uc704\ub294 88.0 ~ 98.0\uc785\ub2c8\ub2e4.
\uc794\uc5ec 0.1%
\uc678\uad00 \ud770\uc0c9 \ub610\ub294 \uc720\ubc31\uc0c9 \ubd84\ub9d0 \ub610\ub294 \uacfc\ub9bd
\uac00\uc2a4 \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub798\ud53c\uc6a9 \uace0\uc815\uc561\uc73c\ub85c \uc0ac\uc6a9
\ud3ec\uc7a5 25kg\/\ubc30\ub7f4
\uc911\uad6d \uc6d0\uc0b0\uc9c0
\uc0c1\ub958 \uc6d0\ub8cc \uc885\uc790 1,4 \ubaa8\ub178\ubd80\ud0c4\ub514\uc62c, \ubaa8\ub178\uc5d0\ud0c4\uc62c\uc544\ubbfc<\/p>\n

\uc758\uc57d\ud488 \ubd80\ud615\uc81c \ud3ec\ube44\ub3c8 K90(C6H9NO)n\uc758 \ud2b9\uc131<\/p>\n

\ud3f4\ub9ac\uc5d4\ud53c\ub9ac\ub3c8, \ud3f4\ub9ac\ube44\ub2d0\ud53c\ub864\ub9ac\ub3c8, \ud3f4\ub9acn-\ube44\ub2d0\ubd80\ud2f8\ub77d\ud0d0\uc73c\ub85c\ub3c4 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \ubc31\uc0c9 \ub610\ub294 \uc720\ubc31\uc0c9\uc774\uba70 \ubb34\ucde8 \ub610\ub294 \uac70\uc758 \ubb34\ucde8\uc774\uba70 \ud761\uc2b5\uc131\uc774 \uc788\uace0 \uc27d\uac8c \ud750\ub974\ub294 \ubb34\uc815\ud615 \ubd84\ub9d0\uc785\ub2c8\ub2e4. \ubb3c, \uc5d0\ud0c4\uc62c, \ud074\ub85c\ub85c\ud3ec\ub984\uc5d0 \uc6a9\ud574\ub418\uace0 \uc5d0\ud2f8\uacfc \uc544\uc138\ud1a4\uc5d0\ub294 \uc6a9\ud574\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ubcf8 \uc81c\ud488\uc758 \uc218\uc6a9\uc561\uc740 \uc77c\uc815\ud55c \uc810\ub3c4\ub97c \uac00\uc9c0\uace0 \uc788\uc73c\uba70, 10% \uc774\ud558\uc758 \uc6a9\uc561\uc758 \uc810\ub3c4\ub294 \uae30\ubcf8\uc801\uc73c\ub85c \ubb3c\uc758 \uc810\ub3c4\uc640 \ub3d9\uc77c\ud569\ub2c8\ub2e4. \ubcf8 \uc81c\ud488\uc740 1-\uc5d0\ud2f8\ub80c-2-\ud53c\ub864\ub9ac\ub3c8 30% ~ 60% \uc218\uc6a9\uc561\uc744 \uc554\ubaa8\ub2c8\uc544 \ub610\ub294 \uc544\ubbfc, \ucd09\ub9e4\ub85c \uacfc\uc0b0\ud654\uc218\uc18c \uc874\uc7ac \ud558\uc5d0 \uad50\ucc28\uc0ac\uc2ac \ub2e8\ub3c5\uc911\ud569 \uc815\uc81c \ud6c4 50\u2103 \uc628\ub3c4\uc5d0\uc11c \uc815\uc81c\ud55c \uc81c\ud488\uc785\ub2c8\ub2e4. \uacb0\ud569, \uc99d\uc810\uc81c, \ud604\ud0c1 \ubcf4\uc870\uc81c, \ubd84\uc0b0\uc81c, \uc6a9\ud574 \ubcf4\uc870\uc81c, \ubcf5\ud569\ud654 \ubc0f \ud544\ub984 \ud615\uc131 \ub4f1\uc758 \ud2b9\uc131\uacfc \uae30\ub2a5\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc99d\uc810\uc81c, \ubca8 \ud604\ud0c1\uc81c, \ubd84\uc0b0\uc81c, \uacf5\uc6a9\ub9e4, \ucc29\ud654\uc81c, \uc804\uad6c\uccb4 \uc57d\ubb3c \uc804\ub2ec\uccb4, \uc758\uc57d\ud488\uc758 \ubc14\uc778\ub354, \ud544\ub984 \ud615\uc131 \uc7ac\ub8cc, \ucf54\ud305 \uc7ac\ub8cc \ubc0f \uc11c\ubc29\uc131 \uc7ac\ub8cc.<\/p>","protected":false},"excerpt":{"rendered":"

Povidone is a water-soluble synthetic polymer, the key ingredient is N-vinylidenone. It is a polymer with high adhesive properties, and is important as a binder for wet granulation of solid preparations. Its properties make it a critical excipient in various oral liquid systems, suspensions and local drug development applicationsSolubility: easily soluble in water and halogenated hydrocarbon solvents, alcohols, amines, nitroalkanes and low molecular fatty acids, insoluble in acetone, ethyl, turpentine, aliphatic hydrocarbons and alicyclic hydrocarbons and other few solvents. It is compatible with most inorganic salts and various resins.Properties: Hydrophilic and easy to flow white or nearly white powder, with a slight odor. PVP is divided into four stages according to its average molecular weight size, which is usually expressed by the K value, and different K values represent the corresponding average molecular weight range of PVP. The K value is actually an eigenvalue related to the relative viscosity of\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"attr":[120],"class_list":["post-1729","post","type-post","status-publish","format-standard","hentry","category-problems"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1729","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=1729"}],"version-history":[{"count":4,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1729\/revisions"}],"predecessor-version":[{"id":1733,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1729\/revisions\/1733"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=1729"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=1729"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=1729"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=1729"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}