{"id":1405,"date":"2024-02-20T16:22:07","date_gmt":"2024-02-20T08:22:07","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=1405"},"modified":"2024-02-20T16:22:07","modified_gmt":"2024-02-20T08:22:07","slug":"what-is-pvp-va64","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/what-is-pvp-va64\/","title":{"rendered":"PVP va64 \ub780 \u200b\u200b\ubb34\uc5c7\uc785\ub2c8\uae4c?"},"content":{"rendered":"<p>\ud654\ud559\uc801 \uc124\uba85<br \/>\uc81c\ud488\uba85: \ucf54\ud3ec\ube44\ub3c8(PVP VA 64)<br \/>\ube0c\ub79c\ub4dc \uc774\ub984: BOVIDONE\u00aeVA64<br \/>CAS \ubc88\ud638: 25086-89-9<br \/>\ud654\ud559\uba85: \ube44\ub2d0\ud53c\ub864\ub9ac\ub3c8\/\ube44\ub2d0 \uc544\uc138\ud14c\uc774\ud2b8 \uacf5\uc911\ud569\uccb4<br \/>CEP \ub4f1\ub85d\ubc88\ud638: 2019-199<br \/>DMF \ub4f1\ub85d\ubc88\ud638 : 33953<\/p>\n<p>\ubb3c\ub9ac\ud654\ud559\uc801 \uc131\uc9c8<br \/>\ubc31\uc0c9 \ub0b4\uc9c0 \ub2f4\ud669\uc0c9 \ud761\uc2b5\uc131 \ubd84\ub9d0, \uc720\ub3d9\uc131\uc774 \uc591\ud638\ud558\uace0 \ud761\uc2b5\uc131\uc774 POvidone\ubcf4\ub2e4 \ub0ae\uc2b5\ub2c8\ub2e4.<br \/>\ubb3c, \uc5d0\ud0c4\uc62c \ubc0f \uae30\ud0c0 \uc720\uae30 \uc6a9\ub9e4\uc5d0 \uc6a9\ud574\ub418\uba70 \uc720\ub9ac \uc804\uc774 \uc628\ub3c4\uac00 \ub0ae\uc2b5\ub2c8\ub2e4.<br \/>\uc6b0\uc218\ud55c \ud544\ub984 \ud615\uc131\uc81c\uc785\ub2c8\ub2e4.<\/p>\n<p>\uc81c\ud488\uaddc\uaca9<br \/>USP\/NF, EP, JP, BP \ud45c\uc900 \ucda9\uc871<\/p>\n<p>\uc804\ud615\uc801\uc778 \ud2b9\uc131<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-1406\" src=\"https:\/\/www.yearnintl.com\/wp-content\/uploads\/2024\/02\/2024022008175334.jpg\" alt=\"Electron microscope scan of copovidone\" width=\"710\" height=\"324\" \/><\/p>\n<p>\uc0ac\uc591<\/p>\n<table border=\"0\" width=\"100%\" cellspacing=\"1\" cellpadding=\"1\" bgcolor=\"#fff\">\n<tbody>\n<tr>\n<td bgcolor=\"#404040\">\uc77c\ub828\ubc88\ud638<\/td>\n<td bgcolor=\"#1784c7\">\ud14c\uc2a4\ud2b8 \ud56d\ubaa9<\/td>\n<td bgcolor=\"#1784c7\">\uc720\ub7fd \u200b\u200b\uc57d\uc804 \ud45c\uc900<\/td>\n<\/tr>\n<tr>\n<td>1<\/td>\n<td>\uc810\ub3c4<\/td>\n<td>27.0-33.0<\/td>\n<\/tr>\n<tr>\n<td bgcolor=\"#f2f2f2\">2<\/td>\n<td bgcolor=\"#f2f2f2\">\uac74\uc870 \uc190\uc2e4<\/td>\n<td bgcolor=\"#f2f2f2\">\u22645.0%<\/td>\n<\/tr>\n<tr>\n<td>3<\/td>\n<td>\ubd88\uc21c\ubb3c A(2-\ud53c\ub864\ub9ac\ub3c8)<\/td>\n<td>\u22640.5%<\/td>\n<\/tr>\n<tr>\n<td bgcolor=\"#f2f2f2\">4<\/td>\n<td bgcolor=\"#f2f2f2\">\uacfc\uc0b0\ud654\ubb3c<\/td>\n<td bgcolor=\"#f2f2f2\">\u2264400ppm<\/td>\n<\/tr>\n<tr>\n<td>5<\/td>\n<td>\ud5e4\ube44\uba54\ud0c8<\/td>\n<td>\u226410ppm<\/td>\n<\/tr>\n<tr>\n<td bgcolor=\"#f2f2f2\">6<\/td>\n<td bgcolor=\"#f2f2f2\">\ubd88\uc21c\ubb3c B(1-\ube44\ub2d0-2-\ud53c\ub864\ub9ac\ub3c8)<\/td>\n<td bgcolor=\"#f2f2f2\">\u226410ppm<\/td>\n<\/tr>\n<tr>\n<td>7<\/td>\n<td>\ubd88\uc21c\ubb3c C(\ucd08\uc0b0\ube44\ub2d0)<\/td>\n<td>\u226410ppm<\/td>\n<\/tr>\n<tr>\n<td bgcolor=\"#f2f2f2\">8<\/td>\n<td bgcolor=\"#f2f2f2\">\uc6d0\uc18c \ubd88\uc21c\ubb3c<\/td>\n<td bgcolor=\"#f2f2f2\">ICH Q3D\uc5d0 \ubd80\ud569<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\uc801\uc6a9\ud558\ub2e4<br \/>\uc9c1\uc811 \uc555\ucc29 \uc815\uc81c\uc6a9 \uac74\uc2dd \uc811\ucc29\uc81c, \uc2b5\uc2dd \uacf5\uc815\uc5d0 \uc758\ud55c \uc815\uc81c, \ucea1\uc290 \ubc0f \uacfc\ub9bd\uc6a9 \uc811\ucc29\uc81c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4.<br \/>\uc6b0\uc218\ud55c \ud53c\ub9c9\ud615\uc131\uc81c\ub85c\uc11c \uc815\uc81c, \uc785\uc790, \ud3a0\ub81b, \ub2f9\uc758\ucf54\ud305\uc561\uc758 \ucf54\ud305\uc561 \ubc0f \uad6d\uc18c\uc6a9 \uc2a4\ud504\ub808\uc774\uc5d0 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ubcf8 \uc81c\ud488\uc73c\ub85c \uc81c\uc870\ub41c \ud544\ub984 \ucf54\ud305 \ubc0f \uc2a4\ud504\ub808\uc774 \ud544\ub984\uc740 \uc720\uc5f0\uc131\uc774 \uc6b0\uc218\ud558\uace0 \ud761\uc218\uc728\uc774 \ub0ae\uc73c\uba70 \uac00\uc18c\uc131\uc774 \ub192\uace0 \uc810\ub3c4\uac00 \ub0ae\uc2b5\ub2c8\ub2e4.<br \/>\uc6b0\uc218\ud55c \uac00\uc18c\uc131\uacfc \ub0ae\uc740 \uc720\ub9ac \uc804\uc774 \uc628\ub3c4\ub85c \uc778\ud574 \ud56b\uba5c\ud2b8 \uc555\ucd9c\uc744 \ud1b5\ud55c \uc81c\uc57d \uace0\uccb4 \ubd84\uc0b0\uccb4 \uc81c\uc870\uc5d0 \uc801\ud569\ud569\ub2c8\ub2e4.<br \/>\uc57d\ubb3c\uc758 \uc6a9\ud574\ub3c4 \ubc0f \uc0dd\uccb4 \uc774\uc6a9\ub960\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4.<br \/>\uc218\ubd84\uc5d0 \ubbfc\uac10\ud55c \ucc98\ubc29\uc744 \uc704\ud55c \ud0c1\uc6d4\ud55c \uc811\ucc29\ub825;<\/p>\n<p>\ud3ec\uc7a5 \ubc0f \ubcf4\uad00<br \/>25kg \ud310\uc9c0 \ub610\ub294 \ud50c\ub77c\uc2a4\ud2f1 \ub4dc\ub7fc \ud3ec\uc7a5;<br \/>\uac74\uc870\ud558\uace0 \ubc00\ud3d0\ub41c \uc6a9\uae30\uc5d0 \ubcf4\uad00\ud558\uc2ed\uc2dc\uc624.<\/p>","protected":false},"excerpt":{"rendered":"<p>Chemical descriptionProduct Name: Copovidone (PVP VA 64)Brand Name: BOVIDONE\u00aeVA64CAS number: 25086-89-9Chemical name: vinylpyrrolidone\/vinyl acetate copolymerCEP Registration number: 2019-199DMF registration number: 33953 Physicochemical propertiesWhite to light yellow hygroscopic powder, good fluidity, hygroscopicity lower than POvidone;Soluble in water, ethanol and other organic solvents, the glass transition temperature is low;It is an excellent film forming agent; Product standardMeets USP\/NF, EP, JP, BP standards Typical characteristic specification serial number test item european pharmacopeas standards 1 viscosity 27.0-33.0 2 loss on drying \u22645.0% 3 Impurity A (2-pyrrolidone) \u22640.5% 4 peroxide \u2264400ppm 5 heavy metal \u226410ppm 6 Impurity B (1-vinyl-2-pyrrolidone) \u226410ppm 7 Impurity C (vinyl acetate) \u226410ppm 8 Elemental impurity accord with ICH Q3D ApplyUsed as a dry adhesive for direct pressing tablets, adhesives for tablets, capsules and granules by wet process;As an excellent film forming agent, it is used in the coating solution of tablets, particles, pellets and sugar-coated core and in the spray for\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"attr":[109],"class_list":["post-1405","post","type-post","status-publish","format-standard","hentry","category-problems"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=1405"}],"version-history":[{"count":1,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1405\/revisions"}],"predecessor-version":[{"id":1407,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1405\/revisions\/1407"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=1405"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=1405"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=1405"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=1405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}