{"id":1087,"date":"2024-02-01T15:22:23","date_gmt":"2024-02-01T07:22:23","guid":{"rendered":"https:\/\/www.yearnintl.com\/?p=1087"},"modified":"2024-02-01T15:22:23","modified_gmt":"2024-02-01T07:22:23","slug":"polyvinylpyrrolidone-pvp-drug-excipients-2","status":"publish","type":"post","link":"https:\/\/www.yearnintl.com\/ko\/problems\/polyvinylpyrrolidone-pvp-drug-excipients-2\/","title":{"rendered":"\ud3f4\ub9ac\ube44\ub2d0\ud53c\ub864\ub9ac\ub3c8 PVP \uc57d\ubb3c \ubd80\ud615\uc81c"},"content":{"rendered":"<p>PVP\ub294 \uacb0\ud569\uc131\uc774 \uc88b\uace0 \uc6a9\ud574\ub825\uc774 \uac15\ud569\ub2c8\ub2e4. PVP \ud615\uc131 \uc815\uc81c\ub294 \uc18c\ud654\uad00\uc5d0 \ud761\uc218\ub41c \ud6c4 \uccab \ubc88\uc9f8 \ube60\ub978 \uc6a9\ud574\uac00 \uc774\ub8e8\uc5b4\uc9c0\uba70 \uc815\uc81c\uc758 \uad6d\uc18c \ud33d\ucc3d \ubc0f \ubd84\ud574, \uc57d\ubb3c \uc870\uac01\uc758 \ubc29\ucd9c, \uadf8\ub7f0 \ub2e4\uc74c \uc57d\ubb3c\uc758 \uc6a9\ud574 \ubc0f \ud761\uc218\ub97c \uac00\uc18d\ud654\ud558\uc5ec \ud6a8\ub2a5\uc5d0 \ube60\ub978 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. \uc57d\uc758. PVP\ub294 \ubb3c\uacfc \ub300\ubd80\ubd84\uc758 \uc720\uae30 \uc6a9\ub9e4\uc5d0 \uc6a9\ud574\ub418\uba70, \uc774\ub294 \uc120\ud0dd\ud560 \uc218 \uc788\ub294 \uc6a9\ub9e4\uac00 \uac70\uc758 \uc5c6\ub294 \uc57d\ubb3c\uc758 \uacbd\uc6b0 \ud2b9\ud788 \uc911\uc694\ud569\ub2c8\ub2e4. PVP\uac00 \ud2b9\ud788 \ud574\uc678\uc5d0\uc11c \uc758\uc57d\ud488 \uc815\uc81c\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\ub294 \uac83\uc740 \uc774\ub7ec\ud55c \uc774\uc720 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n<p><img decoding=\"async\" class=\"alignnone size-full wp-image-1088\" src=\"https:\/\/www.yearnintl.com\/wp-content\/uploads\/2024\/02\/Pharmaceutical-excipients.jpg\" alt=\"Pharmaceutical-excipients\" width=\"1024\" height=\"683\" \/><br \/>\uacf5\uce68\uc804\uc81c<br \/>\uc57d\ubb3c \ubd80\ud615\uc81c\ub85c\uc11c PVP\uc758 \ub610 \ub2e4\ub978 \uc911\uc694\ud55c \uc6a9\ub3c4\ub294 \uacf5\uce68\uc81c\uc774\uba70, \uc77c\ubd80 \uc57d\ubb3c\uc740 \ud6a8\ub2a5\uc774 \uc88b\uc9c0\ub9cc \uce58\uba85\uc801\uc778 \ub2e8\uc810\uc740 \ubb3c\uc5d0 \ub300\ud55c \uc6a9\ud574\ub3c4\uac00 \ub9e4\uc6b0 \uc791\uc544\uc11c \uc0dd\uccb4 \uc774\uc6a9\ub960\uc774 \ud06c\uac8c \uac10\uc18c\ud558\uace0 \uc77c\ubd80 \uc218\uc6a9\uc131 \ubb3c\uc9c8\uc744 \uc0ac\uc6a9\ud55c\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774\ub4e4 \uc57d\ubb3c\uc744 \uacf5\uce68\uc2dc\ucf1c \uc57d\ubb3c\uc758 \uc6a9\ud574\ub3c4\uc640 \uc6a9\ud574 \uc18d\ub3c4\ub97c \ud5a5\uc0c1\uc2dc\ud0a4\uace0 \ubcf5\uc6a9\ub7c9\uc744 \uc904\uc774\uace0 \ud6a8\uacfc\uc758 \ud6a8\ub2a5\uc744 \ud5a5\uc0c1\uc2dc\ud0b5\ub2c8\ub2e4. \ubd88\uc6a9\uc131 \uc57d\ubb3c\uc758 \uacf5\uce68\uc804\uc81c\ub85c PVP\uac00 \ub110\ub9ac \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p>\uacb0\ud569\uc81c, \uc6a9\ub9e4\uc99d\uac15\uc81c, \ubd95\uad34\uc81c, \uc9c0\uc5f0\uc81c \ub4f1<br \/>\uace0\ud615 \uc57d\ubb3c\uc5d0\uc11c PVP\ub294 \uc811\ucc29\uc81c, \uc6a9\ud574\uc81c, \ubd95\uad34\uc81c \ubc0f \uc9c0\uc5f0\uc81c\ub85c \uc0ac\uc6a9\ud560 \uc218 \uc788\uc73c\uba70 \uc57d\ubb3c \ud544\ub984 \ucf54\ud305, \ucea1\uc290 \uaecd\uc9c8 \ubc0f \uc81c\uc5b4 \ubc29\ucd9c \ud544\ub984\uc73c\ub85c\ub3c4 \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. PVP\ub85c \ub9cc\ub4e0 \uc57d\ubb3c \ud544\ub984 \ucf54\ud2b8\uc640 \ucea1\uc290 \uaecd\uc9c8\uc740 \uac74\uc870\ud55c \ud658\uacbd\uc5d0\uc11c \ubd80\uc11c\uc9c0\uae30 \uc27d\uc9c0 \uc54a\uc73c\uba70 \uc801\uc808\ud55c \uc591\uc758 PVP\uc640 \uae30\ud0c0 \ubd88\uc6a9\uc131 \ud3f4\ub9ac\uba38\uac00 \ud568\uaed8 \uc11c\ub85c \ub2e4\ub978 \ub450\uaed8\uc640 \uae30\uacf5 \ud06c\uae30\uc758 \ud22c\uacfc\uc131 \ud544\ub984\uc744 \ub9cc\ub4e4\uc5b4 \uc57d\ubb3c \ud1b5\uacfc \uc18d\ub3c4\ub97c \uc870\uc815\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud544\ub984\uc744 \ud1b5\ud574 \uc81c\uc5b4 \ubc29\ucd9c \ud6a8\uacfc\ub97c \uc5bb\uc2b5\ub2c8\ub2e4.<\/p>","protected":false},"excerpt":{"rendered":"<p>PVP has good bonding properties and strong dissolution ability. PVP formed tablets, after taking in the digestive tract, the first rapid dissolution, is the local expansion and disintegration of the tablets, the release of drug fragments, and then accelerate the dissolution and absorption of the drug, play a rapid role in the efficacy of the drug. PVP is soluble in water and most organic solvents, which is particularly important for drugs with few solvents to choose from. It is for these reasons that PVP has been widely used in pharmaceutical tablets, especially abroad. coprecipitantAnother important use of PVP as drug excipients is co-precipitation agent, some drugs have good efficacy, but its fatal disadvantage is that the solubility in water is very small, resulting in its bioavailability is greatly reduced, the use of some water-soluble substances with these drugs co-precipitation, and then improve the solubility and dissolution rate of drugs, to\u2026<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[79],"attr":[],"class_list":["post-1087","post","type-post","status-publish","format-standard","hentry","category-problems","tag-polyvinylpyrrolidone"],"_links":{"self":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/comments?post=1087"}],"version-history":[{"count":1,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1087\/revisions"}],"predecessor-version":[{"id":1089,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/posts\/1087\/revisions\/1089"}],"wp:attachment":[{"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/media?parent=1087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/categories?post=1087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/tags?post=1087"},{"taxonomy":"attr","embeddable":true,"href":"https:\/\/www.yearnintl.com\/ko\/wp-json\/wp\/v2\/attr?post=1087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}