Polyvinylpyrrolidone (PVP) was first synthesized by the German company BASF during World War II as an artificial plasma solubilizer. In the pharmaceutical industry, PVP and cellulose derivatives, acrylic compounds are currently internationally recognized as the most important three kinds of synthetic pharmaceutical excipients, whose average molecular weight is generally expressed by the K value of K-15, K-30, K-60, K-90 and other representative molecular weight of about 10,000, 40,000, 160,000, 360,000. PVP has many excellent properties such as solubility, solubilization, film forming, complexation, adhesion and certain surface activity, especially good biocompatibility without any irritation to the skin, mucous membranes and eyes, so it is widely used in the field of medicine. 1 Used as an adhesive Because PVP is soluble in both water and some common organic solvents, such as ethanol, it can be used in a variety of formulations. For example, the influence of water and heat can be eliminated…